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Erschienen in: Surgical Endoscopy 5/2020

24.07.2019 | 2019 SAGES Oral

Reduction of opioid use after implementation of enhanced recovery after bariatric surgery (ERABS)

verfasst von: Pearl Ma, Aaron Lloyd, Morgan McGrath, Riley Moore, Alice Jackson, Keith Boone, Kelvin Higa

Erschienen in: Surgical Endoscopy | Ausgabe 5/2020

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Abstract

Background

Enhanced recovery after surgery (ERAS) protocols have been extensively proven in lower gastrointestinal surgery to decrease postoperative physiologic stress and length of stay (LOS). ERAS in bariatric surgery (ERABS) varies immensely from each program with inconsistent results with a predominant goal of reducing LOS. Our focus in implementing enhanced recovery after bariatric surgery (ERABS) protocols is aimed at reducing postoperative pain and opioid use.

Methods

This is a retrospective review of patients who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (VSG) at a single high-volume center from June 2016 to October 2017. Patients on previous standard protocol were categorized into “Pre-Liposomal Bupivacaine (LB) group.” After routine use of Exparel™, patients were grouped into “LB group.” After ERABS protocol was initiated, patients were categorized into “ERABS/LB group.” Postoperative opioids were converted to morphine equivalents units (MEU); pain scores, LOS, and 30-day outcomes were analyzed using combination of t test and Mann–Whitney U.

Results

A total of 1340 patients were included in the study: 304 patients in pre-LB group; 754 patients in LB group, and 282 patients in ERABS/LB group. Total hospital opioid use was 58.6 MEU in pre-LB, 40.8 MEU in LB, and 23.8 MEU in ERABS/LB (p = 0.01). ERABS/LB group found a 59.5% decline in MEU requirements compared to pre-LB (p < 0.001) and 44.9% of patients did not require any additional narcotics on the floor compared to 0% in pre-LB group (p < 0.001). ERABS/LB LOS was an average of 1.48 days compared to 1.54 days in pre-LB group (p = 0.03) with an overall decrease of 3.74% in readmission rates (p = 0.03).

Conclusions

Implementation of ERABS significantly reduced postoperative opioid use, LOS, and readmissions. With ERABS, a more profound effect was observed than simply adding Exparel™ to preexisting protocols. Almost half of these patients did not require narcotics while recovering on the surgical floor. More studies are required to assess the true effect of ERABS without use of Exparel™.
Literatur
1.
Zurück zum Zitat Hah JM et al (2017) Chronic opioid use after surgery: implications for perioperative management in the face of the opioid epidemic. Anesth Analg 125(5):1733–1740PubMedPubMedCentralCrossRef Hah JM et al (2017) Chronic opioid use after surgery: implications for perioperative management in the face of the opioid epidemic. Anesth Analg 125(5):1733–1740PubMedPubMedCentralCrossRef
2.
Zurück zum Zitat Sun EC et al (2016) Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period. JAMA Intern Med 176(9):1286–1293PubMedPubMedCentralCrossRef Sun EC et al (2016) Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period. JAMA Intern Med 176(9):1286–1293PubMedPubMedCentralCrossRef
3.
Zurück zum Zitat Heinberg LJ et al (2018) Opioids and bariatric surgery: a review and suggested recommendations for assessment and risk reduction. Surg Obes Relat Dis 15(2):314–321PubMedCrossRef Heinberg LJ et al (2018) Opioids and bariatric surgery: a review and suggested recommendations for assessment and risk reduction. Surg Obes Relat Dis 15(2):314–321PubMedCrossRef
4.
Zurück zum Zitat Smith ME et al (2018) Effect of new persistent opioid use on physiologic and psychologic outcomes following bariatric surgery. Surg Endosc 33(8):2649–2656PubMedCrossRef Smith ME et al (2018) Effect of new persistent opioid use on physiologic and psychologic outcomes following bariatric surgery. Surg Endosc 33(8):2649–2656PubMedCrossRef
5.
Zurück zum Zitat Raebel MA et al (2013) Chronic use of opioid medications before and after bariatric surgery. JAMA 310(13):1369–1376PubMedCrossRef Raebel MA et al (2013) Chronic use of opioid medications before and after bariatric surgery. JAMA 310(13):1369–1376PubMedCrossRef
6.
Zurück zum Zitat Gustafsson UO et al (2019) Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS((R))) Society Recommendations: 2018. World J Surg 43(3):659–695PubMedCrossRef Gustafsson UO et al (2019) Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS((R))) Society Recommendations: 2018. World J Surg 43(3):659–695PubMedCrossRef
7.
Zurück zum Zitat Jung AD et al (2018) Enhanced recovery after colorectal surgery: can we afford not to use it? J Am Coll Surg 226(4):586–593PubMedCrossRef Jung AD et al (2018) Enhanced recovery after colorectal surgery: can we afford not to use it? J Am Coll Surg 226(4):586–593PubMedCrossRef
8.
Zurück zum Zitat Awad S et al (2014) Enhanced recovery after bariatric surgery (ERABS): clinical outcomes from a tertiary referral bariatric centre. Obes Surg 24(5):753–758PubMedCrossRef Awad S et al (2014) Enhanced recovery after bariatric surgery (ERABS): clinical outcomes from a tertiary referral bariatric centre. Obes Surg 24(5):753–758PubMedCrossRef
9.
Zurück zum Zitat Blanchet M-C et al (2017) Experience with an enhanced recovery after surgery (ERAS) program for bariatric surgery: comparison of MGB and LSG in 374 patients. Obes Surg 27(7):1896–1900PubMedCrossRef Blanchet M-C et al (2017) Experience with an enhanced recovery after surgery (ERAS) program for bariatric surgery: comparison of MGB and LSG in 374 patients. Obes Surg 27(7):1896–1900PubMedCrossRef
10.
Zurück zum Zitat Singh PM et al (2017) Efficiency and safety effects of applying ERAS protocols to bariatric surgery: a systematic review with meta-analysis and trial sequential analysis of evidence. Obes Surg 27(2):489–501PubMedCrossRef Singh PM et al (2017) Efficiency and safety effects of applying ERAS protocols to bariatric surgery: a systematic review with meta-analysis and trial sequential analysis of evidence. Obes Surg 27(2):489–501PubMedCrossRef
11.
Zurück zum Zitat Sinha A et al (2017) Enhanced recovery after bariatric surgery in the severely obese, morbidly obese, super-morbidly obese and super-super morbidly obese using evidence-based clinical pathways: a comparative study. Obes Surg 27(3):560–568PubMedCrossRef Sinha A et al (2017) Enhanced recovery after bariatric surgery in the severely obese, morbidly obese, super-morbidly obese and super-super morbidly obese using evidence-based clinical pathways: a comparative study. Obes Surg 27(3):560–568PubMedCrossRef
12.
Zurück zum Zitat Lemanu DP et al (2013) Randomized clinical trial of enhanced recovery versus standard care after laparoscopic sleeve gastrectomy. Br J Surg 100(4):482–489PubMedCrossRef Lemanu DP et al (2013) Randomized clinical trial of enhanced recovery versus standard care after laparoscopic sleeve gastrectomy. Br J Surg 100(4):482–489PubMedCrossRef
13.
Zurück zum Zitat Mannaerts GH et al (2016) Results of implementing an enhanced recovery after bariatric surgery (ERABS) protocol. Obes Surg 26(2):303–312PubMedCrossRef Mannaerts GH et al (2016) Results of implementing an enhanced recovery after bariatric surgery (ERABS) protocol. Obes Surg 26(2):303–312PubMedCrossRef
14.
Zurück zum Zitat Larson DW et al (2014) Outcomes after implementation of a multimodal standard care pathway for laparoscopic colorectal surgery. Br J Surg 101(8):1023–1030PubMedCrossRef Larson DW et al (2014) Outcomes after implementation of a multimodal standard care pathway for laparoscopic colorectal surgery. Br J Surg 101(8):1023–1030PubMedCrossRef
15.
Zurück zum Zitat Liu VX et al (2017) Enhanced recovery after surgery program implementation in 2 surgical populations in an integrated health care delivery system. JAMA Surg 152(7):e171032PubMedPubMedCentralCrossRef Liu VX et al (2017) Enhanced recovery after surgery program implementation in 2 surgical populations in an integrated health care delivery system. JAMA Surg 152(7):e171032PubMedPubMedCentralCrossRef
16.
Zurück zum Zitat Lam J et al (2019) An ERAS protocol for bariatric surgery: is it safe to discharge on post-operative day 1? Surg Endosc 33(2):580–586PubMedCrossRef Lam J et al (2019) An ERAS protocol for bariatric surgery: is it safe to discharge on post-operative day 1? Surg Endosc 33(2):580–586PubMedCrossRef
17.
Zurück zum Zitat Malczak P et al (2017) Enhanced recovery after bariatric surgery: systematic review and meta-analysis. Obes Surg 27(1):226–235PubMedCrossRef Malczak P et al (2017) Enhanced recovery after bariatric surgery: systematic review and meta-analysis. Obes Surg 27(1):226–235PubMedCrossRef
18.
Zurück zum Zitat Khorgami Z et al (2017) Fast track bariatric surgery: safety of discharge on the first postoperative day after bariatric surgery. Surg Obes Relat Dis 13(2):273–280PubMedCrossRef Khorgami Z et al (2017) Fast track bariatric surgery: safety of discharge on the first postoperative day after bariatric surgery. Surg Obes Relat Dis 13(2):273–280PubMedCrossRef
19.
Zurück zum Zitat Hahl T et al (2016) Outcome of laparoscopic gastric bypass (LRYGB) with a program for enhanced recovery after surgery (ERAS). Obes Surg 26(3):505–511PubMedCrossRef Hahl T et al (2016) Outcome of laparoscopic gastric bypass (LRYGB) with a program for enhanced recovery after surgery (ERAS). Obes Surg 26(3):505–511PubMedCrossRef
20.
Zurück zum Zitat Thorell A et al (2016) Guidelines for perioperative care in bariatric surgery: enhanced recovery after surgery (ERAS) society recommendations. World J Surg 40(9):2065–2083PubMedCrossRef Thorell A et al (2016) Guidelines for perioperative care in bariatric surgery: enhanced recovery after surgery (ERAS) society recommendations. World J Surg 40(9):2065–2083PubMedCrossRef
21.
Zurück zum Zitat Barreca M et al (2016) Is there a role for enhanced recovery after laparoscopic bariatric surgery? Preliminary results from a specialist obesity treatment center. Surg Obes Relat Dis 12(1):119–126PubMedCrossRef Barreca M et al (2016) Is there a role for enhanced recovery after laparoscopic bariatric surgery? Preliminary results from a specialist obesity treatment center. Surg Obes Relat Dis 12(1):119–126PubMedCrossRef
22.
Zurück zum Zitat Siddiqui NT et al (2018) The effect of gabapentin on delayed discharge from the postanesthesia care unit: a retrospective analysis. Pain Pract 18(1):18–22PubMedCrossRef Siddiqui NT et al (2018) The effect of gabapentin on delayed discharge from the postanesthesia care unit: a retrospective analysis. Pain Pract 18(1):18–22PubMedCrossRef
23.
Zurück zum Zitat Andersen LP et al (2014) A systematic review of peri-operative melatonin. Anaesthesia 69(10):1163–1171PubMedCrossRef Andersen LP et al (2014) A systematic review of peri-operative melatonin. Anaesthesia 69(10):1163–1171PubMedCrossRef
24.
Zurück zum Zitat Ivry M et al (2017) Melatonin premedication improves quality of recovery following bariatric surgery—a double blind placebo controlled prospective study. Surg Obes Relat Dis 13(3):502–506PubMedCrossRef Ivry M et al (2017) Melatonin premedication improves quality of recovery following bariatric surgery—a double blind placebo controlled prospective study. Surg Obes Relat Dis 13(3):502–506PubMedCrossRef
25.
Zurück zum Zitat Hansen MV et al (2015) Melatonin for pre- and postoperative anxiety in adults. Cochrane Database Syst Rev 4:Cd009861 Hansen MV et al (2015) Melatonin for pre- and postoperative anxiety in adults. Cochrane Database Syst Rev 4:Cd009861
Metadaten
Titel
Reduction of opioid use after implementation of enhanced recovery after bariatric surgery (ERABS)
verfasst von
Pearl Ma
Aaron Lloyd
Morgan McGrath
Riley Moore
Alice Jackson
Keith Boone
Kelvin Higa
Publikationsdatum
24.07.2019
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 5/2020
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-019-07006-3

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