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Erschienen in:
04.01.2019 | Images in Obstetrics and Gynecology
Reference ranges for ultrasound measurements of fetal kidneys in a cohort of low-risk pregnant women
Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2019
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Purpose
Alterations in renal dimensions may be an early manifestation of deviation from normality, with possible repercussions beyond intrauterine life. The objective of this study was to establish reference curves for fetal kidney dimensions and volume from 14 to 40 weeks of gestation.
Methods
This is a prospective longitudinal study of 115 Brazilian participants in the “WHO multicentre study for the development of growth standards from fetal life to childhood: the fetal component”. Pregnant women with clinical and sociodemographic characteristics allowing the full potential fetal growth were followed up from the first trimester until delivery. These women underwent serial sonographic evaluation of fetal kidneys. The longitudinal, anteroposterior and transverse diameters of both fetal kidneys were measured, in addition to calculation of kidney volume. By quantile regression analysis, reference curves of renal measurements related to gestational age were built.
Results
Standard normal sonographic values of renal biometry were defined during pregnancy. Reference values for the 10th, 50th and 90th centiles of different fetal kidney measurements (longitudinal, anteroposterior, transverse and volume) from the 14th to the 40th week of gestation were fitted.
Conclusion
The reference curves presented should be of the utmost importance for screening and diagnosis of alterations in renal development during the intrauterine period.