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01.06.2009 | Original Article

Regional diastolic function by tissue Doppler echocardiography in systemic sclerosis: correlation with clinical variables

verfasst von: Edoardo Rosato, Stefania Maione, Antonio Vitarelli, Anna Giunta, Luca Fontanella, Laura Tanturri de Horatio, Francesco Cacciatore, Michele Proietti, Simonetta Pisarri, Felice Salsano

Erschienen in: Rheumatology International | Ausgabe 8/2009

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Abstract

The incidence of left ventricular (LV) diastolic dysfunction is increased in systemic sclerosis (SSc), while systolic dysfunction is present in a small percentage of patients. The aim of this study was to asses the LV “regional” diastolic abnormalities in SSc patients by the mean of Doppler tissue imaging (DTI). Echocardiographic echo-Doppler (DE) and DTI parameters were analyzed for 67 SSc patients: abnormal E/A ratio at DE was detected in 24, while abnormal e/a at DTI was observed in 41. A significant prevalence of DTI diastolic abnormalities in the segments reflecting longitudinal versus those reflecting radial LV motion was found. The segments of the basal regions of LV myocardium were significantly more involved than those of the middle portion. Linear correlation was observed between the extent of the diastolic abnormalities and the duration of disease. Longitudinal myocardial systolic velocities were significantly reduced in patients with abnormal e/a DTI.

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Titel: Regional diastolic function by tissue Doppler echocardiography in systemic sclerosis: correlation with clinical variables
verfasst von: Edoardo Rosato
Stefania Maione
Antonio Vitarelli
Anna Giunta
Luca Fontanella
Laura Tanturri de Horatio
Francesco Cacciatore
Michele Proietti
Simonetta Pisarri
Felice Salsano
Publikationsdatum: 01.06.2009
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 8/2009
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-008-0827-x

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