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Erschienen in: The Indian Journal of Pediatrics 5/2018

07.03.2018 | Editorial commentary

Regional Genotyping of Rotavirus: Role in Vaccine Development

verfasst von: Anshu Srivastava, Rishi Bolia

Erschienen in: Indian Journal of Pediatrics | Ausgabe 5/2018

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Excerpt

Rotavirus is the most common cause of severe acute diarrhea in young children worldwide, resulting in >2 lac deaths annually [1]. Viral serotypes are defined on the basis of outer capsid proteins VP4 (P serotype) and VP7 (G serotype). Till date, at least 24 G and 33 P genotypes have been identified and 12 G and 15 P serotypes are known to infect humans. Development of a protective immune response after primary infection that reduces symptom severity on re-infection is the basis for oral rotavirus vaccine development. …
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Metadaten
Titel
Regional Genotyping of Rotavirus: Role in Vaccine Development
verfasst von
Anshu Srivastava
Rishi Bolia
Publikationsdatum
07.03.2018
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 5/2018
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-018-2648-6

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