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26.01.2017 | Editorial

Regulated and Unregulated Clinical Trials of Stem Cell Therapies for Stroke

verfasst von: Michael G. Liska, Marci G. Crowley, Cesar V. Borlongan

Erschienen in: Translational Stroke Research | Ausgabe 2/2017

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Excerpt

Stem cell therapies have been demonstrated in the laboratory as an effective option in treating a number of neurological disorders, including stroke. By targeting the subacute and chronic phases of stroke, stem cell therapies offer the advantage of extending the intervention window which has traditionally been oppressively small. Although substantial laboratory data support this therapeutic potential, transitioning stem cell treatments into approved clinical products has proven difficult. The reasons for this are many, including fundamental complications which have accompanied non-traditional pharmaceuticals such as difficulties in achieving treatment/dosing/cell type consensus and also the regulatory and legislative hindrances which have plagued stem cell advancement. Fortunately, translational lab-to-clinic research endeavors are being made in all of the abovementioned categories, allowing the initiation of limited clinical trials of stem cell therapies for stroke patients. …

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Titel: Regulated and Unregulated Clinical Trials of Stem Cell Therapies for Stroke
verfasst von: Michael G. Liska
Marci G. Crowley
Cesar V. Borlongan
Publikationsdatum: 26.01.2017
Verlag: Springer US
Erschienen in: Translational Stroke Research / Ausgabe 2/2017
Print ISSN: 1868-4483
Elektronische ISSN: 1868-601X
DOI: https://doi.org/10.1007/s12975-017-0522-x

Increased 12/15-Lipoxygenase Leads to Widespread Brain Injury Following Global Cerebral Ischemia

Original Article

Association Between Dehydration and Short-Term Risk of Ischemic Stroke in Patients with Atrial Fibrillation

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Higher Cerebrospinal Fluid pH may Contribute to the Development of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

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Role of Glibenclamide in Brain Injury After Intracerebral Hemorrhage

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Induction of Perivascular Neural Stem Cells and Possible Contribution to Neurogenesis Following Transient Brain Ischemia/Reperfusion Injury

Original Article

Early Erythrolysis in the Hematoma After Experimental Intracerebral Hemorrhage

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Die elektronische Patientenakte kommt: Das sollten Sie jetzt wissen

12.01.2025
Elektronische Patientenakte
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Am 15. Januar geht die „ePA für alle“ zunächst in den Modellregionen an den Start. Doch schon bald soll sie in allen Praxen zum Einsatz kommen. Was ist jetzt zu tun? Was müssen Sie wissen? Wir geben in einem FAQ Antworten auf 21 Fragen.

Update Neurologie

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Springer Medizin

Regulated and Unregulated Clinical Trials of Stem Cell Therapies for Stroke

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Role of Glibenclamide in Brain Injury After Intracerebral Hemorrhage

Induction of Perivascular Neural Stem Cells and Possible Contribution to Neurogenesis Following Transient Brain Ischemia/Reperfusion Injury

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Die elektronische Patientenakte kommt: Das sollten Sie jetzt wissen

Update Neurologie

Springer Medizin

Excerpt

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