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Erschienen in: Seminars in Immunopathology 5/2016

06.05.2016 | Review

Regulatory roles of mast cells in immune responses

verfasst von: Hideaki Morita, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae

Erschienen in: Seminars in Immunopathology | Ausgabe 5/2016

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Abstract

Mast cells are important immune cells for host defense through activation of innate immunity (via toll-like receptors or complement receptors) and acquired immunity (via FcεRI). Conversely, mast cells also act as effector cells that exacerbate development of allergic or autoimmune disorders. Yet, several lines of evidence show that mast cells act as regulatory cells to suppress certain inflammatory diseases. Here, we review the mechanisms by which mast cells suppress diseases.
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Metadaten
Titel
Regulatory roles of mast cells in immune responses
verfasst von
Hideaki Morita
Hirohisa Saito
Kenji Matsumoto
Susumu Nakae
Publikationsdatum
06.05.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Seminars in Immunopathology / Ausgabe 5/2016
Print ISSN: 1863-2297
Elektronische ISSN: 1863-2300
DOI
https://doi.org/10.1007/s00281-016-0566-0

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