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Journal of Anesthesia

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22.05.2018 | Original Article

Relationship between fresh frozen plasma to packed red blood cell transfusion ratio and mortality in cardiovascular surgery

verfasst von: Akito Tsukinaga, Takuma Maeda, Shunsuke Takaki, Nobuaki Michihata, Yoshihiko Ohnishi, Takahisa Goto

Erschienen in: Journal of Anesthesia | Ausgabe 4/2018

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Abstract

Purpose

The aim of this study was to examine the relationship between FFP (fresh frozen plasma)/pRBC (packed red blood cell) transfusion ratio and outcomes in patients undergoing cardiovascular surgery.

Methods

This is a single center retrospective cohort study performed in a cardiovascular center. Patients undergoing cardiovascular surgery between January 2012 and October 2016 with or without massive transfusion (n = 1453). Patients’ outcomes were compared based on FFP/pRBC transfusion ratio (FFP/pRBC > 1 or FFP/pRBC ≤ 1).

Results

In hospital mortality and rate of stroke and myocardial infarction was significantly higher in patients with less than 1 of FFP/pRBC transfusion ratio only in patients with massive transfusion (3.0 vs 8.8%, p = 0.001; 0.7 vs 6.4%, p < 0.001; 1.0 vs 3.2%, p = 0.047, respectively).

Conclusions

Higher FFP/RBC ratio was associated with reduced risk of death, stroke and myocardial infarction only in patients with cardiovascular surgery receiving massive transfusion. Clinicians should be aware that judicious FFP replacement plays a critical role in the successful management of massive transfusion in cardiac surgery.

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Titel: Relationship between fresh frozen plasma to packed red blood cell transfusion ratio and mortality in cardiovascular surgery
verfasst von: Akito Tsukinaga
Takuma Maeda
Shunsuke Takaki
Nobuaki Michihata
Yoshihiko Ohnishi
Takahisa Goto
Publikationsdatum: 22.05.2018
Verlag: Springer Japan
Erschienen in: Journal of Anesthesia / Ausgabe 4/2018
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI: https://doi.org/10.1007/s00540-018-2508-6

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Springer Medizin

Relationship between fresh frozen plasma to packed red blood cell transfusion ratio and mortality in cardiovascular surgery

Abstract

Purpose

Methods

Results

Conclusions

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Ärztliche Empathie hilft gegen Rückenschmerzen

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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