Skip to main content
main-content

01.11.2011 | Retinal Disorders | Ausgabe 11/2011

Graefe's Archive for Clinical and Experimental Ophthalmology 11/2011

Relationship between retinal nerve fiber layer thickness and driving ability in patients with human immunodeficiency virus infection

Zeitschrift:
Graefe's Archive for Clinical and Experimental Ophthalmology > Ausgabe 11/2011
Autoren:
Sarah Cheng, Helaina Klein, Dirk-Uwe Bartsch, Igor Kozak, Thomas D. Marcotte, William R. Freeman
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1007/​s00417-011-1735-4) contains supplementary material, which is available to authorized users.

Abstract

Background

The aim of this work is to study the possible association between retinal nerve fiber layer (NFL) thickness and driving ability.

Methods

Thirty-eight drivers including 22 HIV-positive (HIV+) and 16 age-matched HIV-negative controls participants underwent a full ophthalmologic evaluation, including assessment of retinal NFL thickness. In the undilated state with standard optical correction and under standard illumination they also completed a computer-based, wide field-of-view driving simulation in which they were to obey traffic laws, engage in crash avoidance, and pass slower automobiles. Crashes, speeding and traffic light tickets, and off-road excursions contributed to a weighted score of driving errors.

Results

HIV-seropositive participants had a significantly higher weighted error score than control participants (18.4 [9.2] vs. 11.1 [4.5], p = 0.006). NFL thickness was significantly correlated with driving errors (r = −0.51, p = 0.025); there was a trend for participants with a CD4 nadir <100 to have more errors than those with a nadir >100 (29.7 [13.2] vs. 19.3 [8.4], p = 0.056). The highest number of driving errors occurred in individuals with both CD4 <100 and NFL thickness <80.

Conclusions

Driving ability may be impacted by reductions in retinal nerve fiber layer thickness. Physicians should consider the potential impact that more complex ophthalmologic conditions in HIV-infected patients may have on driving performance.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Zusatzmaterial
ESM 1 (DOC 22.5 kb)
417_2011_1735_MOESM1_ESM.doc
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 11/2011

Graefe's Archive for Clinical and Experimental Ophthalmology 11/2011 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

01.08.2019 | Erkrankungen der Hornhaut | CME | Ausgabe 8/2019

Neurotrophe Keratopathie

Grundlagen, Diagnostik und Therapie

22.07.2019 | DFP-Fortbildung | Ausgabe 4/2019 Open Access

Aktuelle Möglichkeiten der visuellen Rehabilitation

28.06.2019 | Neuroradiologie | CME | Ausgabe 7/2019

Neuroradiologie in der Augenheilkunde

19.06.2019 | Leitlinien, Stellungnahmen und Empfehlungen | Ausgabe 8/2019

Bewertung und Qualitätssicherung refraktiv-chirurgischer Eingriffe durch die DOG und den BVA – KRC-Empfehlungen

Stand Februar 2019