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10.01.2022 | Original Paper

Reliability and validity of using EQ-5D-5L among healthy and adolescents with major mental health disorders in Ethiopia

verfasst von: Abraham G. Welie, Elly Stolk, Clara Mukuria, Yared Belete Belay, Murray D. Krahn, Beate Sander, Gebremedhin Beedemariam Gebretekle

Erschienen in: The European Journal of Health Economics | Ausgabe 7/2022

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Abstract

Background

The EQ-5D is a validated and widely used generic measure of health-related quality of life (HRQoL) in both healthy individuals and those with various medical conditions. The objective of this study was to test whether EQ-5D-5L is reliable and valid for use among school sample adolescents and those with major mental health disorders in Ethiopia.

Methods

Participants were recruited from ten sub-districts comprising the Butajira Rural Health Programme (BRHP) and Butajira major mental health disorders center. Data were collected using an Amharic (Ethiopia) EQ-5D-5L self-complete-paper and the questionnaire was administered 10 days after the first completion for test–retest procedures. Two-way mixed-effects models absolute intraclass correlation coefficient (ICC) was used to test reliability of the instrument while Kruskal–Wallis rank test with pairwise comparison was used to assess the known group validity of the instrument.

Results

There were 501 (201 school sample and 300 adolescents with major mental health disorders) participants recruited and 497 were included in the sample for analysis. The ICC was high (ICC > 0.7, p < 0.001) for all EQ-5D-5L dimensions, EQ-5D-5L utility index and EQ-VAS scores. The findings revealed that the Amharic EQ-5D-5L has significant known group validity as shown by the difference in scores among various disease group (depression, schizophrenia, and bipolar) and experience of chronic illness.

Conclusions

The results shows that the Amharic EQ-5D-5L is reliable and valid instrument for the measurement of HRQoL among adolescent populations in Ethiopia.
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Metadaten
Titel
Reliability and validity of using EQ-5D-5L among healthy and adolescents with major mental health disorders in Ethiopia
verfasst von
Abraham G. Welie
Elly Stolk
Clara Mukuria
Yared Belete Belay
Murray D. Krahn
Beate Sander
Gebremedhin Beedemariam Gebretekle
Publikationsdatum
10.01.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
The European Journal of Health Economics / Ausgabe 7/2022
Print ISSN: 1618-7598
Elektronische ISSN: 1618-7601
DOI
https://doi.org/10.1007/s10198-021-01412-y