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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Renal and suprarenal insufficiency secondary to familial Mediterranean fever associated with amyloidosis: a case report

Journal of Medical Case Reports > Ausgabe 1/2011
Ahmet Burak Toros, Fusun Erdenen, Nagehan Didem Sari, Serkan Gokcay
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

ABT analyzed and interpreted the patient data regarding the diseases. FE, NDS, and SG were major contributors to the writing of the manuscript. All authors read and approved the final manuscript.



Familial Mediterranean fever is an autosomal recessive disease that predominantly affects people of the Mediterranean coast. One of the most frequent complications of the disease is amyloidosis. This clinical entity is known as secondary (also called AA) amyloidosis.

Case presentation

In this report, we describe the case of a 33-year-old Turkish man with familial Mediterranean fever and chronic renal insufficiency. He was admitted to our clinic with symptoms of suprarenal insufficiency. The patient died three months later as a result of cardiac arrest.


Our aim is to make a contribution to the literature by reporting a case of combined insufficiency due to the accumulation of renal and adrenal amyloid in a patient with familial Mediterranean fever, which has very rarely been described in the literature. We hope that adrenal insufficiency, which becomes fatal if not diagnosed and treated rapidly, will come to mind as easily as chronic renal failure in clinical practice.

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