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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 11/2019

24.08.2019 | Consensus Conference

Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup

verfasst von: Rupesh Raina, Manpreet K Grewal, Martha Blackford, Jordan M. Symons, Michael J. G. Somers, Christoph Licht, Rajit K Basu, Sidharth Kumar Sethi, Deepa Chand, Gaurav Kapur, Mignon McCulloch, Arvind Bagga, Vinod Krishnappa, Hui-Kim Yap, Marcelo de Sousa Tavares, Timothy E Bunchman, Michelle Bestic, Bradley A Warady, Maria Díaz-González de Ferris

Erschienen in: Pediatric Nephrology | Ausgabe 11/2019

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Abstract

Background

Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT).

Methods

We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed.

Results and Conclusions

We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides.
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Metadaten
Titel
Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup
verfasst von
Rupesh Raina
Manpreet K Grewal
Martha Blackford
Jordan M. Symons
Michael J. G. Somers
Christoph Licht
Rajit K Basu
Sidharth Kumar Sethi
Deepa Chand
Gaurav Kapur
Mignon McCulloch
Arvind Bagga
Vinod Krishnappa
Hui-Kim Yap
Marcelo de Sousa Tavares
Timothy E Bunchman
Michelle Bestic
Bradley A Warady
Maria Díaz-González de Ferris
Publikationsdatum
24.08.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 11/2019
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-019-04319-2

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