Reply to: “All that glitters is not gold – new reconstruction methods using Deauville criteria for patient reporting”

Excerpt

We thank the Editor-in-Chief for allowing us the opportunity to reply to Barrington et al. [1] and provide some insight into the issue of advanced algorithms in PET imaging of lymphoma patients. We believe that, although advances in PET technology require scientific evaluation, they are a chance to improve the diagnostic/prognostic ability of PET, and should not be considered to be the source of a detrimental effect on Deauville scoring until proven otherwise. In the case of discrepancies between former and new PET systems, studies seeking to determine which reconstruction method provides the best patient risk stratification should be the gold standard. Our main point is that the impact of newer reconstruction methods on Deauville scoring and delta standardized uptake value (ΔSUV), including at least point spread function (PSF) modelling, is in fact only minimal. …