Anzeige
Erschienen in:
02.04.2018 | Letter to the Editor
Reply to the letter to the editor: Lymph node metastasis of adenocarcinoma and different definitions of sm1 cancer in the esophagus
Erschienen in: Journal of Gastroenterology | Ausgabe 6/2018
Einloggen, um Zugang zu erhaltenExcerpt
Thank you for your very helpful comments. We totally understand Dr. Takubo’s points. The diagnosis of cancer invasion depth may differ substantially between surgical specimen which is cut into 5-mm slices and endoscopic resected specimen which is cut into 2-mm slices. This difference may lead to misinterpretation of metastatic rate. We therefore show individual data of surgical specimens and endoscopic resected specimens in Tables 1 and 2.
Table 1
Rate of metastasis in surgical specimens
|
LVI (−) and poorly comp (−)
|
LVI (+) or poorly comp (+)
|
||
|---|---|---|---|
|
≤ 3 cm
|
3 cm <
|
||
|
SMM
|
0% (0/13 lesions)
|
0% (0/1 lesions)
|
0% (0/0 lesions)
|
|
LPM
|
0% (0/10 lesions)
|
0% (0/4 lesions)
|
0% (0/0 lesions)
|
|
DMM
|
0% (0/15 lesions)
|
0% (0/3 lesions)
|
83.3% (5/6 lesions)
|
|
SM 1–500 µm
|
0% (0/8 lesions)
|
0% (0/5 lesions)
|
30% (3/10 lesions)
|
|
SM 500 µm
|
9.5% (2/21 lesions)
|
23.1% (3/13 lesions)
|
40.7% (44/108 lesions)
|
Table 2
Rate of metastasis in endoscopic resected specimens
|
LVI (−) and poorly comp (−)
|
LVI (+) or poorly comp (+)
|
||
|---|---|---|---|
|
≤ 3 cm
|
3 cm <
|
||
|
SMM
|
0% (0/31 lesions)
|
0% (0/5 lesions)
|
0% (0/1 lesions)
|
|
LPM
|
0% (0/31 lesions)
|
0% (0/3 lesions)
|
0% (0/2 lesions)
|
|
DMM
|
0% (0/67 lesions)
|
0% (0/3 lesions)
|
44.4% (4/9 lesions)
|
|
SM 1–500 µm
|
0% (0/24 lesions)
|
25.0% (1/4 lesions)
|
0% (0/8 lesions)
|
|
SM 500 µm
|
7.1% (1/14 lesions)
|
20.0% (1/5 lesions)
|
23.5(8/34 lesions)
|