Ausgabe 1/2006
Inhalt (147 Artikel)
Upregulated Genes In Sporadic, Idiopathic Pulmonary Arterial Hypertension
Alasdair J Edgar, Matilde R Chacón, Anne E Bishop, Magdi H Yacoub, Julia M Polak
TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases
Gang Chen, Nasreen Khalil
Maternal smoking during pregnancy increases the risk of recurrent wheezing during the first years of life (BAMSE)
Eva Lannerö, Magnus Wickman, Goran Pershagen, Lennart Nordvall
Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO2-exposed rats
Holger Garn, Anette Siese, Sabine Stumpf, Anka Wensing, Harald Renz, Diethard Gemsa
Inhaled nitric oxide alleviates hyperoxia suppressed phosphatidylcholine synthesis in endotoxin-induced injury in mature rat lungs
Xiaohui Gong, Chunbao Guo, Shibing Huang, Bo Sun
Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma
Harm Maarsingh, John Leusink, I Sophie T Bos, Johan Zaagsma, Herman Meurs
Biochemical and morphological changes in endothelial cells in response to hypoxic interstitial edema
Laura Botto, Egidio Beretta, Rossella Daffara, Giuseppe Miserocchi, Paola Palestini
Tooth loss and obstructive sleep apnoea
Caterina Bucca, Alessandro Cicolin, Luisa Brussino, Andrea Arienti, Alessandra Graziano, Francesco Erovigni, Paolo Pera, Valerio Gai, Roberto Mutani, Giulio Preti, Giovanni Rolla, Stefano Carossa
Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells
Ellena J Growcott, Karen G Spink, Xiaohui Ren, Saliha Afzal, Kathy H Banner, John Wharton
Mucociliary and long-term particle clearance in airways of patients with immotile cilia
Winfried Möller, Karl Häußinger, Löms Ziegler-Heitbrock, Joachim Heyder
Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma
Kristoffer Larsen, Johan Malmström, Marie Wildt, Camilla Dahlqvist, Lennart Hansson, György Marko-Varga, Leif Bjermer, Agneta Scheja, Gunilla Westergren-Thorsson
Selective regulation of MAP kinases and Chemokine expression after ligation of ICAM-1 on human airway epithelial cells
Thomas M Krunkosky, Carla L Jarrett
Budesonide/formoterol and formoterol provide similar rapid relief in patients with acute asthma showing refractoriness to salbutamol
ED Bateman, L Fairall, DM Lombardi, R English
Determinants of mortality for adults with cystic fibrosis admitted in Intensive Care Unit: a multicenter study
Joëlle Texereau, Dany Jamal, Gérald Choukroun, Pierre-Régis Burgel, Jean-Luc Diehl, Antoine Rabbat, Philippe Loirat, Antoine Parrot, Alexandre Duguet, Joël Coste, Daniel Dusser, Dominique Hubert, Jean-Paul Mira
Wnt signalling in lung development and diseases
Judit E Pongracz, Robert A Stockley
EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts
Ying Ji Li, Arata Azuma, Jiro Usuki, Shinji Abe, Kuniko Matsuda, Toshiaki Sunazuka, Takako Shimizu, Yukiyo Hirata, Hirofumi Inagaki, Tomoyuki Kawada, Satoru Takahashi, Shoji Kudoh, Satoshi Omura
Restoration of diaphragmatic function after diaphragm reinnervation by inferior laryngeal nerve; experimental study in rabbits
Stephane Derrey, Eric verin, Annie Laquerrière, Angelique Boishardy de Barros, Yann Lacoume, Pierre Fréger, Jean Paul Marie
Differential regulation of neurotrophin expression in human bronchial smooth muscle cells
Cecilia Kemi, Johan Grunewald, Anders Eklund, Caroline Olgart Höglund
Limited β2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics
Anneke van Veen, Eddy A Wierenga, Robert Westland, Frank R Weller, Guus AM Hart, Henk M Jansen, René E Jonkers
Correction: Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency
Jan Stolk, Barbara Veldhuisen, Laura Annovazzi, Chiara Zanone, Elly M Versteeg, Toine H van Kuppevelt, Jo HM Berden, Willem Nieuwenhuizen, Paolo Iadarola, Maurizio Luisetti
Epigenetics and airways disease
Ian M Adcock, Paul Ford, Kazuhiro Ito, P J Barnes
Effects of CPAP on right ventricular myocardial performance index in obstructive sleep apnea patients without hypertension
Nese Dursunoglu, Dursun Dursunoglu, Sibel Özkurt, Sükrü Gür, Güllü Özalp, Fatma Evyapan
Relation between air pollution and allergic rhinitis in Taiwanese schoolchildren
Bing-Fang Hwang, Jouni JK Jaakkola, Yung-Ling Lee, Ying-Chu Lin, Yue-liang Leon Guo
Prolonged ozone exposure in an allergic airway disease model: Adaptation of airway responsiveness and airway remodeling
An-Soo Jang, Inseon-S Choi, Jae-Hyuk Lee, Chang-Soo Park, Choon-Sik Park
Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β2-agonist use
Annette T Hastie, Min Wu, Gayle C Foster, Gregory A Hawkins, Vikas Batra, Katherine A Rybinski, Rosemary Cirelli, James G Zangrilli, Stephen P Peters
Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo
Uta Griesenbach, Chris Kitson, Escudero Sara Garcia, Raymond Farley, Charanjit Singh, Luci Somerton, Hazel Painter, Rbecca L Smith, Deborah R Gill, Stephen C Hyde, Yu-Hua Chow, Jim Hu, Mike Gray, Mark Edbrooke, Varrie Ogilvie, Gordon MacGregor, Ronald K Scheule, Seng H Cheng, Natasha J Caplen, Eric WFW Alton
Bronchoscopic assessment of airway retention time of aerosolized xylitol
Lakshmi Durairaj, Srividya Neelakantan, Janice Launspach, Janet L Watt, Margaret M Allaman, William R Kearney, Peter Veng-Pedersen, Joseph Zabner
Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation
Nguyet M Nguyen, Leena Pulkkinen, Jessica A Schlueter, Guerrino Meneguzzi, Jouni Uitto, Robert M Senior
Antimicrobial proteins and polypeptides in pulmonary innate defence
Mark P Rogan, Patrick Geraghty, Catherine M Greene, Shane J O'Neill, Clifford C Taggart, Noel G McElvaney
Endotoxin induced peritonitis elicits monocyte immigration into the lung: implications on alveolar space inflammatory responsiveness
Mirko Steinmüller, Mrigank Srivastava, William A Kuziel, John W Christman, Werner Seeger, Tobias Welte, Jürgen Lohmeyer, Ulrich A Maus
Pulmonary vasoconstrictor action of KCNQ potassium channel blockers
Shreena Joshi, Prabhu Balan, Alison M Gurney
Lung fibroblasts from patients with emphysema show markers of senescence in vitro
K-C Müller, L Welker, K Paasch, B Feindt, VJ Erpenbeck, JM Hohlfeld, N Krug, M Nakashima, D Branscheid, H Magnussen, RA Jörres, O Holz
Ca2+-signaling in airway smooth muscle cells is altered in T-bet knock-out mice
Albrecht Bergner, Julia Kellner, Anita Kemp da Silva, Fernando Gamarra, Rudolf M Huber
Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor
Yan Bai, Michael J Sanderson
Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro
Brian N Chorley, Anne L Crews, Yuehua Li, Kenneth B Adler, Michael Minnicozzi, Linda D Martin
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis
Anne Mansson, Mikael Adner, Lars Olaf Cardell
VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway
Qiangsong Tong, Liduan Zheng, Li Lin, Bo Li, Danming Wang, Chuanshu Huang, Dechun Li
Maintained inspiratory activity during proportional assist ventilation in surfactant-depleted cats early after surfactant instillation: phrenic nerve and pulmonary stretch receptor activity
Richard Sindelar, Esther Rieger-Fackeldey, Anders Jonzon, Peter Schaller, Andreas Schulze, Gunnar Sedin
IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling
Gautam Damera, Baoyun Xia, Goverdhan P Sachdev
Neonatal immune responses to TLR2 stimulation: Influence of maternal atopy on Foxp3 and IL-10 expression
Bianca Schaub, Monica Campo, Hongzhen He, David Perkins, Matthew W Gillman, Diane R Gold, Scott Weiss, Ellice Lieberman, Patricia W Finn
Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response
Laurent Robriquet, François Collet, Antoine Tournoys, Thierry Prangère, Rémi Nevière, François Fourrier, Benoît P Guery
CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation
Saula Ravasi, Simona Citro, Barbara Viviani, Valérie Capra, G Enrico Rovati
Passive immunotherapy for influenza A H5N1 virus infection with equine hyperimmune globulin F(ab')2 in mice
Jiahai Lu, Zhongmin Guo, Xinghua Pan, Guoling Wang, Dingmei Zhang, Yanbin Li, Bingyan Tan, Liping Ouyang, Xinbing Yu
The Directly Observed Therapy Short-Course (DOTS) strategy in Samara Oblast, Russian Federation
Y Balabanova, F Drobniewski, I Fedorin, S Zakharova, V Nikolayevskyy, R Atun, R Coker
The role of endothelin-1 in hyperoxia-induced lung injury in mice
Walid Habre, Ferenc Peták, Isabelle Ruchonnet-Metrailler, Yves Donati, Jean-Francois Tolsa, Eniko Lele, Gergely Albu, Morice Beghetti, Constance Barazzone-Argiroffo
Can HRCT be used as a marker of airway remodelling in children with difficult asthma?
S Saglani, G Papaioannou, L Khoo, M Ujita, PK Jeffery, C Owens, DM Hansell, DN Payne, A Bush
Hormonal regulation of alveolarization: structure-function correlation
Samuel J Garber, Huayan Zhang, Joseph P Foley, Hengjiang Zhao, Stephan J Butler, Rodolfo I Godinez, Marye H Godinez, Andrew J Gow, Rashmin C Savani
Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children
Jouni JK Jaakkola, Anna A Kosheleva, Boris A Katsnelson, Sergey V Kuzmin, Larissa I Privalova, John D Spengler
Cigarette smoke exposure facilitates allergic sensitization in mice
Katrien B Moerloose, Lander J Robays, Tania Maes, Guy G Brusselle, Kurt G Tournoy, Guy F Joos
Tissue fibrocytes in patients with mild asthma: A possible link to thickness of reticular basement membrane?
Kristian Nihlberg, Kristoffer Larsen, Anna Hultgårdh-Nilsson, Anders Malmström, Leif Bjermer, Gunilla Westergren-Thorsson
Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator
Sam Tirkos, Susan Newbigging, Van Nguyen, Mary Keet, Cameron Ackerley, Geraldine Kent, Richard F Rozmahel
Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis
Wen Qi Gan, SF Paul Man, Dirkje S Postma, Patricia Camp, Don D Sin
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema
Ingel K Demedts, Tine Demoor, Ken R Bracke, Guy F Joos, Guy G Brusselle
Upper airway dynamics during negative expiratory pressure in apneic and non-apneic awake snorers
A Ferretti, P Giampiccolo, S Redolfi, S Mondini, F Cirignotta, A Cavalli, C Tantucci
Cognitive, emotional, and quality of life outcomes in patients with pulmonary arterial hypertension
Joanne White, Ramona O Hopkins, Eric W Glissmeyer, Natalie Kitterman, C Gregory Elliott
Latent Tuberculosis in HIV positive, diagnosed by the M. Tuberculosis Specific Interferon-γ test
Inger Brock, Morten Ruhwald, Bettina Lundgren, Henrik Westh, Lars R Mathiesen, Pernille Ravn
Inhalation of β2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract
Nico A Maris, Sandrine Florquin, Cornelis van't Veer, Alex F de Vos, Wim Buurman, Henk M Jansen, Tom van der Poll
Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice
Robert Ten Broeke, Rini De Crom, Rien Van Haperen, Vivienne Verweij, Thea Leusink-Muis, Ingrid Van Ark, Fred De Clerck, Frans P Nijkamp, Gert Folkerts
Blood neutrophil activation markers in severe asthma: lack of inhibition by prednisolone therapy
Bhupinder S Mann, Kian Fan Chung
Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway
Matthias Wjst, Janine Altmüller, Theresia Faus-Kessler, Christine Braig, Margret Bahnweg, Elisabeth André
WFDC2 (HE4): A potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung
Lynne Bingle, Simon S Cross, Alec S High, William A Wallace, Doris Rassl, Guanglu Yuan, Ingegerd Hellstrom, Michael A Campos, Colin D Bingle
Health status measurement in COPD: the minimal clinically important difference of the clinical COPD questionnaire
JWH Kocks, MG Tuinenga, SM Uil, JWK van den Berg, E Ståhl, T van der Molen
Exhaled breath condensate cysteinyl leukotrienes and airway remodeling in childhood asthma: a pilot study
Christiane Lex, Angela Zacharasiewicz, Donald NR Payne, Nicola M Wilson, Andrew G Nicholson, Sergei A Kharitonov, Peter J Barnes, Andrew Bush
Expression of Toll-like receptor 2 is up-regulated in monocytes from patients with chronic obstructive pulmonary disease
Jaume Pons, Jaume Sauleda, Verónica Regueiro, Carmen Santos, Meritxell López, Joana Ferrer, Alvar GN Agustí, José A Bengoechea
Role of acetylcholine and polyspecific cation transporters in serotonin-induced bronchoconstriction in the mouse
Wolfgang Kummer, Silke Wiegand, Sibel Akinci, Ignatz Wessler, Alfred H Schinkel, Jürgen Wess, Hermann Koepsell, Rainer V Haberberger, Katrin S Lips
Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages
Khalil Karimi, Hadi Sarir, Esmaeil Mortaz, Joost J Smit, Hossein Hosseini, Sjef J De Kimpe, Frans P Nijkamp, Gert Folkerts
Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children
K Alving, C Janson, L Nordvall
Differences in MAP kinase phosphorylation in response to mechanical strain in asthmatic fibroblasts
Frédérique Le Bellego, Sophie Plante, Jamila Chakir, Qutayba Hamid, Mara S Ludwig
Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD
Paula Rytilä, Tiina Rehn, Helen Ilumets, Annamari Rouhos, Anssi Sovijärvi, Marjukka Myllärniemi, Vuokko L Kinnula
Chronic Obstructive Pulmonary Disease, inflammation and co-morbidity – a common inflammatory phenotype?
Martin J Sevenoaks, Robert A Stockley
Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection
Brian GG Oliver, Sebastian L Johnston, Melissa Baraket, Janette K Burgess, Nicholas JC King, Michael Roth, Sam Lim, Judith L Black
Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness
Chi-Ling Fu, Yi-Ling Ye, Yueh-Lun Lee, Bor-Luen Chiang
Muscarinic receptor signaling in the pathophysiology of asthma and COPD
Reinoud Gosens, Johan Zaagsma, Herman Meurs, Andrew J Halayko
Markers of exacerbation severity in chronic obstructive pulmonary disease
Luigi G Franciosi, Clive P Page, Bartolome R Celli, Mario Cazzola, Michael J Walker, Meindert Danhof, Klaus F Rabe, E Della Oscar Pasqua
Expression of eicosanoid receptors subtypes and eosinophilic inflammation: implication on chronic rhinosinusitis
Claudina Angela Pérez-Novo, Cindy Claeys, Paul Van Cauwenberge, Claus Bachert
Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study
Alison M Wallace, Jian-Qing He, Kelly M Burkett, Jian Ruan, John E Connett, Nicholas R Anthonisen, Peter D Paré, Andrew J Sandford
Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons
R Diel, A Nienhaus, C Lange, K Meywald-Walter, M Forßbohm, T Schaberg
Apoptosis of viral-infected airway epithelial cells limit viral production and is altered by corticosteroid exposure
Gurpreet K Singhera, Tiffany S Chan, Jenny Y Cheng, Timothy Z Vitalis, Kimm J Hamann, Delbert R Dorscheid
Long-term clearance from small airways in subjects with ciliary dysfunction
Maria Lindström, Rolf Falk, Lena Hjelte, Klas Philipson, Magnus Svartengren
Novel insights into the aetiology and pathophysiology of increased airway inflammation during COPD exacerbations
Maria Tsoumakidou, Nikolaos M Siafakas
Pre-natal and post-natal exposure to respiratory infection and atopic diseases development: a historical cohort study
Anne Zutavern, Stephanie von Klot, Ulrike Gehring, Susanne Krauss-Etschmann, Joachim Heinrich
Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?
Argyris Tzouvelekis, Stavros Anevlavis, Demosthenes Bouros
Regulatory role of CD8+ T lymphocytes in bone marrow eosinophilopoiesis
Madeleine Rådinger, Svetlana Sergejeva, Anna-Karin Johansson, Carina Malmhäll, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan Lötvall
CpG DNA modulates interleukin 1β-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells
N William Parilla, Valerie S Hughes, Kristin M Lierl, Hector R Wong, Kristen Page
Susceptibility to ozone-induced airway inflammation is associated with decreased levels of surfactant protein D
S Kierstein, FR Poulain, Y Cao, M Grous, R Mathias, G Kierstein, MF Beers, M Salmon, RA Panettieri Jr, A Haczku
Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran
Matthias Ochs, Markus Schüttler, Guido Stichtenoth, Egbert Herting
Decreased systemic bioavailability of L-arginine in patients with cystic fibrosis
Hartmut Grasemann, Raphael Schwiertz, Corinna Grasemann, Udo Vester, Kurt Racké, Felix Ratjen
RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis
KL Watts, E Cottrell, PR Hoban, MA Spiteri
Decorin and TGF-β 1 polymorphisms and development of COPD in a general population
Cleo C van Diemen, Dirkje S Postma, Judith M Vonk, Marcel Bruinenberg, Ilja M Nolte, H Marike Boezen
Marked stem cell factor expression in the airways of lung transplant recipients
Carla A Da Silva, Mélanie Adda, Marc Stern, Frédéric de Blay, Nelly Frossard, Dominique Israel-Biet
The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations
Michaela Schedel, Martin Depner, Carola Schoen, Stephan K Weiland, Christian Vogelberg, Bodo Niggemann, Susanne Lau, Thomas Illig, Norman Klopp, Ulrich Wahn, Erika von Mutius, Renate Nickel, Michael Kabesch
IgE sensitisation in relation to flow-independent nitric oxide exchange parameters
Andrei Malinovschi, Christer Janson, Thomas Holmkvist, Dan Norbäck, Pekka Meriläinen, Marieann Högman
Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices
Renate Paddenberg, Peter König, Petra Faulhammer, Anna Goldenberg, Uwe Pfeil, Wolfgang Kummer
Reference values for exhaled nitric oxide (reveno) study
Mario Olivieri, Giorgio Talamini, Massimo Corradi, Luigi Perbellini, Antonio Mutti, Claudio Tantucci, Mario Malerba
Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis
Marco Chilosi, Alberto Zamò, Claudio Doglioni, Daniela Reghellin, Maurizio Lestani, Licia Montagna, Serena Pedron, Maria Grazia Ennas, Alessandra Cancellieri, Bruno Murer, Venerino Poletti
Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels
Michael Groth, Tanja Helbig, Veronika Grau, Wolfgang Kummer, Rainer V Haberberger
Lung epithelium as a sentinel and effector system in pneumonia – molecular mechanisms of pathogen recognition and signal transduction
Stefan Hippenstiel, Bastian Opitz, Bernd Schmeck, Norbert Suttorp
Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells
Bernd Schmeck, Kerstin Moog, Janine Zahlten, Vincent van Laak, Philippe Dje N'Guessan, Bastian Opitz, Simone Rosseau, Norbert Suttorp, Stefan Hippenstiel
Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a penitentiary hospital in Georgia
Isdore C Shamputa, Levan Jugheli, Nikoloz Sadradze, Eve Willery, Françoise Portaels, Philip Supply, Leen Rigouts
Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia
Ahmad W Husari, Ghassan S Dbaibo, Hala Bitar, Aline Khayat, Shoghag Panjarian, Michel Nasser, Fadi F Bitar, Marwan El-Sabban, Ghazi Zaatari, Salman M Mroueh
Participation of the PI-3K/Akt-NF-κB signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells
Qiangsong Tong, Liduan Zheng, Li Lin, Bo Li, Danming Wang, Chuanshu Huang, George M Matuschak, Dechun Li
Human bronchial fibroblasts express the 5-lipoxygenase pathway
Anna J James, John F Penrose, Angelica M Cazaly, Stephen T Holgate, Anthony P Sampson
Cysteinyl-leukotrienes in the regulation of β2-adrenoceptor function: an in vitro model of asthma
G Enrico Rovati, Michele Baroffio, Simona Citro, Lorenzo Brichetto, Saula Ravasi, Manlio Milanese, Emanuele Crimi, Vito Brusasco
Peroxisome Proliferator-Activated Receptor α (PPARα) down-regulation in cystic fibrosis lymphocytes
Veerle Reynders, Stefan Loitsch, Constanze Steinhauer, Thomas Wagner, Dieter Steinhilber, Joachim Bargon
Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells
Brant E Isakson, Colin E Olsen, Scott Boitano
Magnetic resonance lung function – a breakthrough for lung imaging and functional assessment? A phantom study and clinical trial
Maren Zapke, Hans-Georg Topf, Martin Zenker, Rainer Kuth, Michael Deimling, Peter Kreisler, Manfred Rauh, Christophe Chefd'hotel, Bernhard Geiger, Thomas Rupprecht
Exposure of neonates to Respiratory Syncytial Virus is critical in determining subsequent airway response in adults
Dahui You, David Becnel, Kai Wang, Michael Ripple, Melissa Daly, Stephania A Cormier
Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM
Gabriela Krasteva, Uwe Pfeil, Marek Drab, Wolfgang Kummer, Peter König
Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity
Gunnar Gudmundsson, Thorarinn Gislason, Eva Lindberg, Runa Hallin, Suppli Charlotte Ulrik, Eva Brøndum, Markku M Nieminen, Tiina Aine, Per Bakke, Christer Janson
Inhaled steroid/long-acting β2 agonist combination products provide 24 hours improvement in lung function in adult asthmatic patients
Jan Lötvall, Stephen Langley, Ashley Woodcock
Pharmacology of airways and vessels in lung slices in situ: role of endogenous dilator hormones
L Moreno, F Perez-Vizcaino, L Harrington, R Faro, G Sturton, PJ Barnes, JA Mitchell
Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline
Dong-Won Lee, Shawna A Shirley, Richard F Lockey, Shyam S Mohapatra
Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation
Clarisse Vandebrouck, Patricia Melin, Caroline Norez, Renaud Robert, Christelle Guibert, Yvette Mettey, Frédéric Becq
Microarray identifies ADAM family members as key responders to TGF-β1 in alveolar epithelial cells
Dominic T Keating, Denise M Sadlier, Andrea Patricelli, Sinead M Smith, Dermot Walls, Jim J Egan, Peter P Doran
Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells
Garrett J O'Brien, Gareth Riddell, J Stuart Elborn, Madeleine Ennis, Grzegorz Skibinski
An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study
Patrick Mallia, Simon D Message, Tatiana Kebadze, Hayley L Parker, Onn M Kon, Sebastian L Johnston
Endogenous laminin is required for human airway smooth muscle cell maturation
Thai Tran, Karol D McNeill, William T Gerthoffer, Helmut Unruh, Andrew J Halayko
Tuberculosis chemotherapy: current drug delivery approaches
Lisa Claire du Toit, Viness Pillay, Michael Paul Danckwerts
A key role for STIM1 in store operated calcium channel activation in airway smooth muscle
Samantha E Peel, Bo Liu, Ian P Hall
Regional differences in the pattern of airway remodeling following chronic allergen exposure in mice
Jeremy A Hirota, Russ Ellis, Mark D Inman
Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction
Dedmer Schaafsma, I Sophie T Bos, Annet B Zuidhof, Johan Zaagsma, Herman Meurs
Altered intercellular communication in lung fibroblast cultures from patients with idiopathic pulmonary fibrosis
Angela Trovato-Salinaro, Elisa Trovato-Salinaro, Marco Failla, Claudio Mastruzzo, Valerio Tomaselli, Elisa Gili, Nunzio Crimi, Filippo Daniele Condorelli, Carlo Vancheri
Airway smooth muscle as a target of asthma therapy: history and new directions
Luke J Janssen, Kieran Killian
Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione
Zhanna Servetnyk, Jelena Krjukova, Benjamin Gaston, Khalequz Zaman, Lena Hjelte, Godfried M Roomans, Anca Dragomir
Role of TNFα in pulmonary pathophysiology
Srirupa Mukhopadhyay, John R Hoidal, Tapan K Mukherjee
Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice
Brendon J Hanson, Adrianus CM Boon, Angeline PC Lim, Ashley Webb, Eng Eong Ooi, Richard J Webby
Peak exercise capacity estimated from incremental shuttle walking test in patients with COPD: a methodological study
Ragnheiður Harpa Arnardóttir, Margareta Emtner, Hans Hedenström, Kjell Larsson, Gunnar Boman
Clinical implications for Vascular Endothelial Growth Factor in the lung: friend or foe?
Andriana I Papaioannou, Konstantinos Kostikas, Panagoula Kollia, Konstantinos I Gourgoulianis
Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice
Laura McKinley, Jiyoun Kim, Gerald L Bolgos, Javed Siddiqui, Daniel G Remick
The genetics of chronic obstructive pulmonary disease
Alice M Wood, Robert A Stockley
A self-rating scale for patient-perceived side effects of inhaled corticosteroids
Juliet M Foster, Eric van Sonderen, Amanda J Lee, Robbert Sanderman, Antoon Dijkstra, Dirkje S Postma, Thys van der Molen
Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
Aruna Kode, Se-Ran Yang, Irfan Rahman
Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease
Mirva J Peltoniemi, Paula H Rytilä, Terttu H Harju, Ylermi M Soini, Kaisa M Salmenkivi, Lloyd W Ruddock, Vuokko L Kinnula
Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice
Rachida Legssyer, François Huaux, Jean Lebacq, Monique Delos, Etienne Marbaix, Patrick Lebecque, Dominique Lison, Bob J Scholte, Pierre Wallemacq, Teresinha Leal
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
Dominique MA Bullens, Els Truyen, Liesbeth Coteur, Ellen Dilissen, Peter W Hellings, Lieven J Dupont, Jan L Ceuppens
Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study
David G Parr, Andrew J White, Darren L Bayley, Peter J Guest, Robert A Stockley
Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury
Marco Failla, Tiziana Genovese, Emanuela Mazzon, Elisa Gili, Carmelo Muià, Mariangela Sortino, Nunzio Crimi, Achille P Caputi, Salvatore Cuzzocrea, Carlo Vancheri
Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis
Richard Kraemer, David N Baldwin, Roland A Ammann, Urs Frey, Sabina Gallati
The pulmonary effects of intravenous adenosine in asthmatic subjects
Nausherwan K Burki, Mahmud Alam, Lu-Yuan Lee
Airway inflammation contributes to health status in COPD: a cross-sectional study
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Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study
René E Jonkers, Theo A Bantje, René Aalbers
Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort
Robert J Hancox, Richie Poulton, D Robin Taylor, Justina M Greene, Christene R McLachlan, Jan O Cowan, Erin M Flannery, G Peter Herbison, Malcolm R Sears, Nicholas J Talley
Neutrophil cannibalism – a back up when the macrophage clearance system is insufficient
Kristina Rydell-Törmänen, Lena Uller, Jonas S Erjefält
Hypoxia and dehydroepiandrosterone in old age: a mouse survival study
Edouard H Debonneuil, Janine Quillard, Etienne-Emile Baulieu
Following damage, the majority of bone marrow-derived airway cells express an epithelial marker
Heather MacPherson, Pamela A Keir, Carol J Edwards, Sheila Webb, Julia R Dorin
Arsenic trioxide, a potent inhibitor of NF-κB, abrogates allergen-induced airway hyperresponsiveness and inflammation
Lin-Fu Zhou, Yi Zhu, Xue-Fan Cui, Wei-Ping Xie, Ai-Hua Hu, Kai-Sheng Yin
Improved outcomes in patients with chronic obstructive pulmonary disease treated with salmeterol compared with placebo/usual therapy: results of a meta-analysis
Robert A Stockley, Philip J Whitehead, Michael K Williams