Ausgabe 1/2020
Inhalt (326 Artikel)
Therapeutic effect of subcutaneous injection of low dose recombinant human granulocyte-macrophage colony-stimulating factor on pulmonary alveolar proteinosis
Fen Zhang, Dong Weng, Yiliang Su, Chengsheng Yin, Li Shen, Yuan Zhang, Ying Zhou, Qiuhong Li, Yang Hu, Huiping Li
The impact of palliative care on quality of life, anxiety, and depression in idiopathic pulmonary fibrosis: a randomized controlled pilot study
Katherine Janssen, Drew Rosielle, Qi Wang, Hyun Joo Kim
Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis
Timothy H. Harries, Victoria Rowland, Christopher J. Corrigan, Iain J. Marshall, Lucy McDonnell, Vibhore Prasad, Peter Schofield, David Armstrong, Patrick White
Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study
Rachel Denholm, Esther T. van der Werf, Alastair D. Hay
Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis
Benjamin F. Hartley, Neil C. Barnes, Sally Lettis, Chris H. Compton, Alberto Papi, Paul Jones
Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis
David Bennett, Paolo Cameli, Nicola Lanzarone, Loredana Carobene, Nicola Bianchi, Annalisa Fui, Luigi Rizzi, Laura Bergantini, Giuseppe Cillis, Miriana d’Alessandro, Maria Antonietta Mazzei, Rosa Metella Refini, Piersante Sestini, Elena Bargagli, Paola Rottoli
Ongoing challenges in pulmonary fibrosis and insights from the nintedanib clinical programme
Claudia Valenzuela, Sebastiano Emanuele Torrisi, Nicolas Kahn, Manuel Quaresma, Susanne Stowasser, Michael Kreuter
Porcine versus bovine surfactant therapy for RDS in preterm neonates: pragmatic meta-analysis and review of physiopathological plausibility of the effects on extra-pulmonary outcomes
Silvia Foligno, Daniele De Luca
SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b+ cells
Cuiping Fu, Shengyu Hao, Zilong Liu, Liang Xie, Xu Wu, Xiaodan Wu, Shanqun Li
Characteristic chest CT findings for progressive cavities in Mycobacterium avium complex pulmonary disease: a retrospective cohort study
Yohei Oshitani, Seigo Kitada, Ryuya Edahiro, Kazuyuki Tsujino, Hiroyuki Kagawa, Kenji Yoshimura, Keisuke Miki, Mari Miki, Hiroshi Kida
The European MultiPartner IPF registry (EMPIRE): validating long-term prognostic factors in idiopathic pulmonary fibrosis
Tanja Tran, Martina Šterclová, Nesrin Mogulkoc, Katarzyna Lewandowska, Veronika Müller, Marta Hájková, Mordechai R. Kramer, Dragana Jovanović, Jasna Tekavec-Trkanjec, Michael Studnicka, Natalia Stoeva, Karel Hejduk, Ladislav Dušek, Samy Suissa, Martina Vašáková, Beata Zolnowska, Vladimír Bartoš, Hradec Králové, Robert Slivka, Ladislav Lacina, Martina Doubková, Radka Bittenglová, Magdalena Martusewicz-Boros, Monika Žurková, Imrich Jonner, Amelia Szymanowska-Narloch, Małgorzata Sobiecka, Vladimíra Lošťáková, Marzena Trzaska-Sobczak, Richard Tyl, Pawel Sliwinski, Miklós Zsiray, Anikó Bohács, Sebastian Majewski, Hana Šuldová, Katarzyna Lewandowska, Bohumil Matula, Lenka Šišková, Ján Plutinský, Ana Jakić, Štefan Tóth, Zoltán Balikó, Margita Bučeková, Jana Pšíkalová, Tomasz Stachura, František Petřík, Jan Anton, Jaroslav Lněnička, Marina Roksandić Milenkovic, Imre Lajkó, Vladimír Řihák, Zsuzsanna Szalai, Paulina Jurek, Aleksander Kania, Štefan Laššán, Tatjana Pejcic, Pavel Reiterer, Lukasz Borucki, Renata Králová, Pavlína Musilová, Tomáš Snížek, Daniel Doležal, Jiří Homolka, Hana Hortvíková, Suzana Mladinov, Peter Palúch, Roman Hrdina, Maria Szilasi, Violeta Vučinić-Mihailović, Róbert Vyšehradský, Radka Mokošová, Agata Nowicka, Tatjana Radjenovic Petkovic
Impact of diffusing lung capacity before and after neoadjuvant concurrent chemoradiation on postoperative pulmonary complications among patients with stage IIIA/N2 non-small-cell lung cancer
Sumin Shin, Yong Soo Choi, Jae Jun Jung, Yunjoo Im, Sun Hye Shin, Danbee Kang, Jong Ho Cho, Hong Kwan Kim, Jhingook Kim, Jae Ill Zo, Young Mog Shim, Keunchil Park, Myung-Ju Ahn, Yong Chan Ahn, Genehee Lee, Juhee Cho, Ho Yun Lee, Hye Yun Park
Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs
Yifang Liao, Ping Li, Yanxia Wang, Hong Chen, Shangwei Ning, Dongju Su
The stability of blood Eosinophils in chronic obstructive pulmonary disease
Gabriella H. Long, Thomas Southworth, Umme Kolsum, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Lung-protective ventilation worsens ventilator-induced diaphragm atrophy and weakness
Xian-Long Zhou, Xiao-Jun Wei, Shao-Ping Li, Hao-Li Ma, Yan Zhao
Reduced risk of clinically important deteriorations by ICS in COPD is eosinophil dependent: a pooled post-hoc analysis
Mona Bafadhel, Dave Singh, Christine Jenkins, Stefan Peterson, Thomas Bengtsson, Peter Wessman, Malin Fagerås
Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST)
Amaia Artaraz, Megan L. Crichton, Simon Finch, Hani Abo-Leyah, Pieter Goeminne, Stefano Aliberti, Thomas Fardon, James D. Chalmers
A comparison of tiotropium, long-acting β2-agonists and leukotriene receptor antagonists on lung function and exacerbations in paediatric patients with asthma
Christian Vogelberg, Stanley Goldstein, LeRoy Graham, Alan Kaplan, Alberto de la Hoz, Eckard Hamelmann
Reduced airway levels of fatty-acid binding protein 4 in COPD: relationship with airway infection and disease severity
Lídia Perea, Ana Rodrigo-Troyano, Elisabet Cantó, Marisol Domínguez-Álvarez, Jordi Giner, Ferran Sanchez-Reus, Judit Villar-García, Sara Quero, Marian García-Núñez, Alicia Marín, Eduard Monsó, Rosa Faner, Alvar Agustí, Silvia Vidal, Oriol Sibila
ZDHXB-101 (3′,5-Diallyl-2, 4′-dihydroxy-[1,1′-biphen-yl]-3,5′-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways
Jun-xia Jiang, Hui-juan Shen, Yan Guan, Yong-liang Jia, Jian Shen, Qi Liu, Qiang-min Xie, Xiao-feng Yan
Neuromuscular blocking agents for acute respiratory distress syndrome: an updated meta-analysis of randomized controlled trials
Zhongjun Zheng, Libing Jiang, Song Zhang, Christophe Guervilly, Mao Zhang, Xia Feng, Jianbo Ding
Fluid intake-related association between urine output and mortality in acute respiratory distress syndrome
Yanfei Shen, Guolong Cai, Shangzhong Chen, Caibao Hu, Jing Yan
Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls
Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser, Manuela Funke-Chambour
Metabolic and cardiorespiratory effects of decreasing lung hyperinflation with budesonide/formoterol in COPD: a randomized, double-crossover, placebo-controlled, multicenter trial
Miguel J. Divo, Michael R. DePietro, John R. Horton, Cherie A. Maguire, Bartolome R. Celli
“Can do, don’t do” are not the lazy ones: a longitudinal study on physical functioning in patients with COPD
Noriane A. Sievi, Thomas Brack, Martin H. Brutsche, Martin Frey, Sarosh Irani, Jörg D. Leuppi, Robert Thurnheer, Malcolm Kohler, Christian F. Clarenbach
The impact of COPD on polyneuropathy: results from the German COPD cohort COSYCONET
K. Kahnert, M. Föhrenbach, T. Lucke, P. Alter, F. T. Trudzinski, R. Bals, J. I. Lutter, H. Timmermann, S. Söhler, S. Förderreuther, D. Nowak, H. Watz, B. Waschki, J. Behr, T. Welte, C. F. Vogelmeier, R. A. Jörres
Correction to: Azithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls
Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser, Manuela Funke-Chambour
Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease
Atsushi Tanno, Naoya Fujino, Mitsuhiro Yamada, Hisatoshi Sugiura, Taizou Hirano, Rie Tanaka, Hirohito Sano, Satoshi Suzuki, Yoshinori Okada, Masakazu Ichinose
Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy
Michael J. McGeachie, Joanne E. Sordillo, Amber Dahlin, Alberta L. Wang, Sharon M. Lutz, Kelan G. Tantisira, Ronald Panganiban, Quan Lu, Satria Sajuthi, Cydney Urbanek, Rachel Kelly, Benjamin Saef, Celeste Eng, Sam S. Oh, Alvin T. Kho, Damien C. Croteau-Chonka, Scott T. Weiss, Benjamin A. Raby, Angel C. Y. Mak, Jose R. Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold, Ann Chen Wu
Progression of fibrosing interstitial lung disease
Alyson W. Wong, Christopher J. Ryerson, Sabina A. Guler
The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse
Antoine Moui, Martin Klein, Dorian Hassoun, Eléonore Dijoux, Marie-Aude Cheminant, Antoine Magnan, Grégory Bouchaud
Correction to: Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis
David Bennett, Paolo Cameli, Nicola Lanzarone, Loredana Carobene, Nicola Bianchi, Annalisa Fui, Luigi Rizzi, Laura Bergantini, Giuseppe Cillis, Miriana d’Alessandro, Maria Antonietta Mazzei, Rosa Metella Refini, Piersante Sestini, Elena Bargagli, Paola Rottoli
Cardiometabolic comorbidities in obstructive sleep apnea patients are related to disease severity, nocturnal hypoxemia, and decreased sleep quality
Stephanie André, Fabio Andreozzi, Chloé Van Overstraeten, Sidali Ben Youssef, Ionela Bold, Sarah Carlier, Alexia Gruwez, Anne-Violette Bruyneel, Marie Bruyneel
Health-related quality of life and symptoms in patients with IPF treated with nintedanib: analyses of patient-reported outcomes from the INPULSIS® trials
Michael Kreuter, Wim A. Wuyts, Marlies Wijsenbeek, Sabrina Bajwah, Toby M. Maher, Susanne Stowasser, Natalia Male, Wibke Stansen, Nils Schoof, Leticia Orsatti, Jeffrey Swigris
Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study
A. M. Fratta Pasini, C. Stranieri, M. Ferrari, U. Garbin, L. Cazzoletti, C. Mozzini, F. Spelta, D. Peserico, L. Cominacini
Periostin plays a critical role in the cell cycle in lung fibroblasts
Tomohito Yoshihara, Yasuhiro Nanri, Satoshi Nunomura, Yukie Yamaguchi, Carol Feghali-Bostwick, Keiichi Ajito, Shoichi Murakami, Masaaki Mawatari, Kenji Izuhara
6′-O-galloylpaeoniflorin regulates proliferation and metastasis of non-small cell lung cancer through AMPK/miR-299-5p/ATF2 axis
Jinying Gao, Lei Song, Huan Xia, Liping Peng, Zhongmei Wen
Impact of COPD and anemia on motor and cognitive performance in the general older population: results from the English longitudinal study of ageing
Inken Padberg, Alice Schneider, Jessica Lee Rohmann, Sean Walter Kelley, Ulrike Grittner, Bob Siegerink
Change in the symptom profile treated as asthma – two cross-sectional studies twenty years apart
Mihkel Pindus, Hans Orru, Rain Jõgi
Epigenetics dysfunction in morbid obesity with or without obstructive sleep apnoea: the EPIMOOSA study
Javier Lázaro, Paloma Clavería, Carmen Cabrejas, José Fernando, Berta Daga, Beatriz Ordoñez, Silvia Segura, David Sanz - Rubio, José M. Marín
Congenital cystic adenomatoid malformations of the lung: an epithelial transcriptomic approach
Guillaume Lezmi, Shamila Vibhushan, Claudia Bevilaqua, Nicolas Crapart, Nicolas Cagnard, Naziha Khen-Dunlop, Christine Boyle-Freyssaut, Alice Hadchouel, Christophe Delacourt
Gender differences in pulmonary arterial hypertension patients with BMPR2 mutation: a meta-analysis
Xiaoyue Ge, Tiantian Zhu, Xinyi Zhang, Ye Liu, Yonglong Wang, Weifang Zhang
Diagnosis of ventilator-associated pneumonia using electronic nose sensor array signals: solutions to improve the application of machine learning in respiratory research
Chung-Yu Chen, Wei-Chi Lin, Hsiao-Yu Yang
Sex differences in lymphoid follicles in COPD airways
Anthony Tam, Naoya Tanabe, Andrew Churg, Joanne L. Wright, James C. Hogg, Don D. Sin
A dose-ranging study of the inhaled dual phosphodiesterase 3 and 4 inhibitor ensifentrine in COPD
Dave Singh, Fernando J. Martinez, Henrik Watz, Thomas Bengtsson, Brian T. Maurer
Patient and site characteristics associated with pirfenidone and nintedanib use in the United States; an analysis of idiopathic pulmonary fibrosis patients enrolled in the Pulmonary Fibrosis Foundation Patient Registry
Colin H. Holtze, Elizabeth A. Freiheit, Susan L. Limb, John L. Stauffer, Karina Raimundo, Wayne T. Pan, Kevin R. Flaherty, Hyun J. Kim
Trends in prevalence and incidence of chronic respiratory diseases from 1990 to 2017
Min Xie, Xiansheng Liu, Xiaopei Cao, Mingzhou Guo, Xiaochen Li
Phenotypic comparison between smoking and non-smoking chronic obstructive pulmonary disease
Sundeep S. Salvi, Bill B. Brashier, Jyoti Londhe, Kanchan Pyasi, Vandana Vincent, Shilpa S. Kajale, Sajid Tambe, Kuldeep Mandani, Arjun Nair, Sze Mun Mak, Sapna Madas, Sanjay Juvekar, Louise E. Donnelly, Peter J. Barnes
The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship
Chin-Chung Shu, Yu-Feng Wei, Yi-Chun Yeh, Hsien-Ho Lin, Chung-Yu Chen, Ping-Huai Wang, Shih-Lung Cheng, Jann-Yuan Wang, Chong-Jen Yu
Resistance of the respiratory system measured with forced oscillation technique (FOT) correlates with bronchial thermoplasty response
Annika W. M. Goorsenberg, Julia N. S. d’Hooghe, Annelies M. Slats, Joost G. van den Aardweg, Jouke T. Annema, Peter I. Bonta
Frequent mutation of hypoxia-related genes in persistent pulmonary hypertension of the newborn
Mingbang Wang, Deyi Zhuang, Mei Mei, Haiyan Ma, Zixiu Li, Fusheng He, Guoqiang Cheng, Guang Lin, Wenhao Zhou
Hospitalisation and mortality in patients with comorbid COPD and heart failure: a systematic review and meta-analysis
Eleanor L. Axson, Kishan Ragutheeswaran, Varun Sundaram, Chloe I. Bloom, Alex Bottle, Martin R. Cowie, Jennifer K. Quint
The efficacy and safety of pharmacological treatments for lymphangioleiomyomatosis
Qi Wang, Mengqi Luo, Bo Xiang, Siyuan Chen, Yi Ji
TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling
Gali Epstein Shochet, Elizabetha Brook, Becky Bardenstein-Wald, David Shitrit
Prevalence and distribution patterns of allergens among children with asthma and asthma-like symptoms in Shanghai, China
Song Mao, Liangxia Wu, Wenjing Shi
Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation
Peng Liu, Kang Miao, Lei Zhang, Yong Mou, Yongjian Xu, Weining Xiong, Jun Yu, Yi Wang
Preterm birth impairs postnatal lung development in the neonatal rabbit model
Thomas Salaets, Margo Aertgeerts, André Gie, Janne Vignero, Derek de Winter, Yannick Regin, Julio Jimenez, Greetje Vande Velde, Karel Allegaert, Jan Deprest, Jaan Toelen
Downregulation of hsa-microRNA-204-5p and identification of its potential regulatory network in non-small cell lung cancer: RT-qPCR, bioinformatic- and meta-analyses
Chang-Yu Liang, Zu-Yun Li, Ting-Qing Gan, Ye-Ying Fang, Bin-Liang Gan, Wen-Jie Chen, Yi-Wu Dang, Ke Shi, Zhen-Bo Feng, Gang Chen
Lung CD4+ Vα2.3+ T-cells in sarcoidosis cohorts with Löfgren’s syndrome
Pernilla Darlington, Susanna Kullberg, Anders Eklund, Johan Grunewald
HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization
Meng-lu Li, Xin-ming Su, Yuan Ren, Xuan Zhao, Ling-fei Kong, Jian Kang
Adaptive NKG2C+ natural killer cells are related to exacerbations and nutritional abnormalities in COPD patients
Sergi Pascual-Guardia, Michelle Ataya, Isabel Ramírez-Martínez, José Yélamos, Roberto Chalela, Salomé Bellido, Miguel López-Botet, Joaquim Gea
Effect of average volume-assured pressure support treatment on health-related quality of life in COPD patients with chronic hypercapnic respiratory failure: a randomized trial
Doaa M. Magdy, Ahmed Metwally
Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production
Geng-Chin Wu, Chung-Kan Peng, Wen-I Liao, Hsin-Ping Pao, Kun-Lun Huang, Shi-Jye Chu
The effects of BAFF on T lymphocytes in chronic obstructive pulmonary disease
Shupei Gao, Jinqing Chen, Jungang Xie, Jianmiao Wang
Cigarette smoke and electronic cigarettes differentially activate bronchial epithelial cells
Christian Herr, Konstantinos Tsitouras, Julia Niederstraßer, Christina Backes, Christoph Beisswenger, Li Dong, Loïc Guillot, Andreas Keller, Robert Bals
Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy – the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial
Kevin J. Anstrom, Imre Noth, Kevin R. Flaherty, Rex H. Edwards, Joan Albright, Amanda Baucom, Maria Brooks, Allan B. Clark, Emily S. Clausen, Michael T. Durheim, Dong-Yun Kim, Jerry Kirchner, Justin M. Oldham, Laurie D. Snyder, Andrew M. Wilson, Stephen R. Wisniewski, Eric Yow, Fernando J. Martinez, Joan Albright, Kevin J. Anstrom, Emily S. Clausen, Joanna Cole, Dahlia Cowhig, Coleen Crespo, Michael Durheim, Jerry Kirchner, Heather Kuehn, Jay Rao, Laurie D. Snyder, Qinghong Yang, Eric Yow
Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials
Jinping Zheng, Jin-fu Xu, Martin Jenkins, Pryseley Nkouibert Assam, Lijiao Wang, Brian J. Lipworth
Evaluation of secondhand smoke effects on CFTR function in vivo
Lawrence W. Rasmussen, Denise Stanford, Krina Patel, S. Vamsee Raju
Mesenchymal stromal cell-derived exosomes improve pulmonary hypertension through inhibition of pulmonary vascular remodeling
Shanshan Zhang, Xiaoli Liu, Li Li Ge, Kailin Li, Yongchao Sun, Fang Wang, Ying Han, Chao Sun, Jue Wang, Wen Jiang, Qian Xin, Chaoyue Xu, Yuan Chen, Ou chen, Zhaohua Zhang, Yun Luan
Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis
Mirco Govoni, Michele Bassi, Stefano Vezzoli, Germano Lucci, Aida Emirova, Marie Anna Nandeuil, Stefano Petruzzelli, Gera L. Jellema, Ebenezer K. Afolabi, Brendan Colgan, Brian Leaker, Oliver Kornmann, Kai Michael Beeh, Henrik Watz, Dave Singh
Hospitalisation patterns of patients with interstitial lung disease in the light of comorbidities and medical treatment – a German claims data analysis
Julia Wälscher, Sabine Witt, Larissa Schwarzkopf, Michael Kreuter
Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis
Gemin Zhang, Jie Zhang, Bowen Wang, Xionglin Zhu, Qiang Wang, Shiming Qiu
A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor
Toby M. Maher, Juliet K. Simpson, Joanna C. Porter, Frederick J. Wilson, Robert Chan, Rhena Eames, Yi Cui, Sarah Siederer, Simon Parry, Julia Kenny, Robert J. Slack, Jagdeep Sahota, Lyn Paul, Peter Saunders, Philip L. Molyneaux, Pauline T. Lukey, Gaia Rizzo, Graham E. Searle, Richard P. Marshall, Azeem Saleem, Arthur R. Kang’ombe, David Fairman, William A. Fahy, Mitra Vahdati-Bolouri
Bronchial thermoplasty reduces airway resistance
David Langton, Kim Bennetts, Peter Noble, Virginia Plummer, Francis Thien
Microbial burden and viral exacerbations in a longitudinal multicenter COPD cohort
Jerome Bouquet, David E. Tabor, Jonathan S. Silver, Varsha Nair, Andrey Tovchigrechko, M. Pamela Griffin, Mark T. Esser, Bret R. Sellman, Hong Jin
Intranasal epinephrine effects on epinephrine pharmacokinetics and heart rate in a nasal congestion canine model
Richard Tuttle, Luca Popescu, Scott Hill, Amber Slanczka, Jeffrey Jankowski, Katherine Barre, Erika Krueger, Desmond Slade, Claire Croutch, Matthew Robben, Zack Mesa, Michael Mesa, Kenneth L. Dretchen
Validation of the portable Bluetooth® Air Next spirometer in patients with different respiratory diseases
Konstantinos P. Exarchos, Athena Gogali, Agni Sioutkou, Christos Chronis, Sofia Peristeri, Konstantinos Kostikas
Changes of DNA methylation are associated with changes in lung function during adolescence
Shadia Khan Sunny, Hongmei Zhang, Faisal I. Rezwan, Caroline L. Relton, A. John Henderson, Simon Kebede Merid, Erik Melén, Jenny Hallberg, S. Hasan Arshad, Susan Ewart, John W. Holloway
Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis
Adrien Carla, Bruno Pereira, Hanifa Boukail, Jules Audard, Nathalie Pinol-Domenech, Manuela De Carvalho, Raiko Blondonnet, Ruoyang Zhai, Dominique Morand, Céline Lambert, Vincent Sapin, Lorraine B. Ware, Carolyn S. Calfee, Julie A. Bastarache, John G. Laffey, Nicole P. Juffermans, Lieuwe D. Bos, Antonio Artigas, Patricia R. M. Rocco, Michael A. Matthay, Daniel F. McAuley, Jean-Michel Constantin, Matthieu Jabaudon
Lung volume dependence of respiratory function in rodent models of diabetes mellitus
Roberta Südy, Álmos Schranc, Gergely H. Fodor, József Tolnai, Barna Babik, Ferenc Peták
Prognostic value of NT-proBNP in patients with severe COVID-19
Lei Gao, Dan Jiang, Xue-song Wen, Xiao-cheng Cheng, Min Sun, Bin He, Lin-na You, Peng Lei, Xiao-wei Tan, Shu Qin, Guo-qiang Cai, Dong-ying Zhang
Effect of high-flow nasal therapy during early pulmonary rehabilitation in patients with severe AECOPD: a randomized controlled study
Lan-Fang Tung, Sheng-Yeh Shen, Hui-Hsuan Shih, Yen-Ting Chen, Chia-te Yen, Shu-Chuan Ho
Factors associated with intraoperative extracorporeal membrane oxygenation support during lung transplantation
Rong Zhang, Yonghao Xu, Ling Sang, Sibei Chen, Yongbo Huang, Lingbo Nong, Chun Yang, Xuesong Liu, Dongdong Liu, Yin Xi, Weiqun He, Bing Wei, Jianxing He, Yimin Li, Xiaoqing Liu
The correlation between CYP4F2 variants and chronic obstructive pulmonary disease risk in Hainan Han population
Yipeng Ding, Yixiu Yang, Quanni Li, Qiong Feng, Dongchuan Xu, Cibing Wu, Jie Zhao, Xiaoli Zhou, Huan Niu, Ping He, Jianfang Liu, Hongxia Yao
Letter to the editor: indacaterol/glycopyrronium/mometasone furoate compared with salmeterol/fluticasone propionate in patients with asthma: a randomized controlled cross-over study
Henrik Watz, Jens M. Hohlfeld, Dave Singh, Jutta Beier, Zuzana Diamant, Jinming Liu, Shucheng Hua, Khalid Abd-Elaziz, Pascale Pinot, Ieuan Jones, Hanns-Christian Tillmann
The influence of chlorine in indoor swimming pools on the composition of breathing phase of professional swimmers
Andrzej S. Swinarew, Arkadiusz J. Stanula, Jadwiga Gabor, Paweł Raif, Jarosław Paluch, Jakub Karpiński, Klaudia Kubik, Hubert Okła, Andrzej Ostrowski, Ewaryst Tkacz, Szymon Skoczyński, Zbigniew Waśkiewicz, Thomas Rosemann, Pantelis T. Nikolaidis, Beat Knechtle
Different expression levels of interleukin-35 in asthma phenotypes
Wei Li, Ruihan Gao, Tong Xin, Peng Gao
Endothelial dysfunction is not a predictor of outcome in chronic obstructive pulmonary disease
Andreas Scherr, Desiree M. Schumann, Meropi Karakioulaki, Léo Franchetti, Werner Strobel, Michael Zellweger, Michael Tamm, Daiana Stolz
Responsiveness and minimal clinically important difference of SGRQ-I and K-BILD in idiopathic pulmonary fibrosis
Thomas Skovhus Prior, Nils Hoyer, Ole Hilberg, Saher Burhan Shaker, Jesper Rømhild Davidsen, Elisabeth Bendstrup
Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitigation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia
Margaret Gilfillan, Pragnya Das, Dilip Shah, Mohammad Afaque Alam, Vineet Bhandari
Impact of baseline symptoms and health status on COPD exacerbations in the FLAME study
Alexander J. Mackay, Konstantinos Kostikas, Nicolas Roche, Stefan-Marian Frent, Petter Olsson, Pascal Pfister, Pritam Gupta, Francesco Patalano, Donald Banerji, Jadwiga A. Wedzicha
Validation of age, PaO2/FlO2 and plateau pressure score in Korean patients with acute respiratory distress syndrome: a retrospective cohort study
Hyeontaek Hwang, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Sang-Min Lee
Alantolactone suppresses inflammation, apoptosis and oxidative stress in cigarette smoke-induced human bronchial epithelial cells through activation of Nrf2/HO-1 and inhibition of the NF-κB pathways
Xiaomin Dang, Beibei He, Qian Ning, Ya Liu, Jianxin Guo, Gang Niu, Mingwei Chen
The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China
Jing Gao, Jun-Qiang Liu, Heng-Jun Wen, Hua Liu, Wei-Dong Hu, Xia Han, Chuan-Xing Li, Xiao-Jun Wang
MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease
Amber N. Johnson, Jack R. Harkema, Amy J. Nelson, John D. Dickinson, Julianna Kalil, Michael J. Duryee, Geoffrey M. Thiele, Balawant Kumar, Amar B. Singh, Rohit Gaurav, Sarah C. Glover, Ying Tang, Debra J. Romberger, Tammy Kielian, Jill A. Poole
IL-33, diet-induced obesity, and pulmonary responses to ozone
David I. Kasahara, Stephanie A. Shore
Increased mortality of acute respiratory distress syndrome was associated with high levels of plasma phenylalanine
Jing Xu, Tingting Pan, Xiaoling Qi, Ruoming Tan, Xiaoli Wang, Zhaojun Liu, Zheying Tao, Hongping Qu, Yi Zhang, Hong Chen, Yihui Wang, Jingjing Zhang, Jie Wang, Jialin Liu
Heme metabolism genes Downregulated in COPD Cachexia
Ava C. Wilson, Preeti L. Kumar, Sool Lee, Margaret M. Parker, Itika Arora, Jarrett D. Morrow, Emiel F. M. Wouters, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Alvar Agusti, Ruth Tal-Singer, Mark T. Dransfield, J. Michael Wells, Surya P. Bhatt, George Washko, Victor J. Thannickal, Hemant K. Tiwari, Craig P. Hersh, Peter J. Castaldi, Edwin K. Silverman, Merry-Lynn N. McDonald
Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells
Yanan Yin, Ganesh Vilas Shelke, Cecilia Lässer, Hjalmar Brismar, Jan Lötvall
Validation of a method to assess emphysema severity by spirometry in the COPDGene study
Mariaelena Occhipinti, Matteo Paoletti, James D. Crapo, Barry J. Make, David A. Lynch, Vito Brusasco, Federico Lavorini, Edwin K. Silverman, Elizabeth A. Regan, Massimo Pistolesi
Differences in airway microbiome and metabolome of single lung transplant recipients
Nirmal S. Sharma, Grant Vestal, Keith Wille, Kapil N. Patel, Feng Cheng, Srinivas Tipparaju, Sultan Tousif, Mudassir M. Banday, Xin Xu, Landon Wilson, Viswam S. Nair, Casey Morrow, Don Hayes Jr, Andreas Seyfang, Stephen Barnes, Jessy S. Deshane, Amit Gaggar
The world is not enough – the value of increasing registry data in idiopathic pulmonary fibrosis
C. C. Moor, M. Kreuter, F. Luppi, W. A. Wuyts
High eosinophil blood counts are associated with a shorter length of hospital stay in exacerbated COPD patients – a retrospective analysis
Timm Greulich, Julia Tüffers, Sina Mager, Anna Eder, Michael Maxheim, Peter Alter, Bernd Schmeck, Claus F. Vogelmeier
Circulating microRNAs correlate to clinical parameters in individuals with allergic and non-allergic asthma
Julie Weidner, Linda Ekerljung, Carina Malmhäll, Nicolae Miron, Madeleine Rådinger
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis
Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki J. Barrett, Robert B. Good, Sarah Brockbank, Simon Cruwys, Henrik Jessen, Grith Lykke Sorensen, Morten Asser Karsdal, Diana Julie Leeming, Jannie Marie Bülow Sand
FluA-p score: a novel prediction rule for mortality in influenza A-related pneumonia patients
Liang Chen, Xiudi Han, Yan Li Li, Chunxiao Zhang, Xiqian Xing
Mesenchymal stem/stromal cells: the therapeutic effects in animal models of acute pulmonary diseases
Sirous Sadeghian Chaleshtori, Mohammad Reza Mokhber Dezfouli, Massoumeh Jabbari Fakhr
Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics
Ryan Brown, Sridesh Nath, Alnardo Lora, Ghassan Samaha, Ziyad Elgamal, Ryan Kaiser, Clifford Taggart, Sinéad Weldon, Patrick Geraghty
The ‘can do, do do’ concept in COPD; quadrant interpretation, affiliation and tracking longitudinal changes
A. J. Alex van ’t Hul, E. H. Noortje Koolen, H. W. Jeroen van Hees, B. Bram van den Borst, M. A. Martijn Spruit
Effects of prostaglandin E1 nebulization of ventilated lung under 60%O2 one lung ventilation on patients’ oxygenation and oxidative stress: a randomised controlled trial
Pengyi Li, Lianbing Gu, Qingming Bian, Jing Tan, Dian Jiao, Fei Wu, Zeping Xu, Lijun Wang
Respond to the letter to the editor by Van’t Hul et al. regarding the published manuscript “can do, don’t do” are not the lazy ones: a longitudinal study on physical functioning in patients with COPD” by Sievi et al.(1)
Noriane A. Sievi, Malcolm Kohler, Christian F. Clarenbach
Role of rhinomanometry in the prediction of therapeutic positive airway pressure for obstructive sleep apnea
Yen-Bin Hsu, Stanley Yung-Chuan Liu, Ming-Ying Lan, Yun-Chen Huang, I-Shiang Tzeng, Ming-Chin Lan
MiR-223 plays a protecting role in neutrophilic asthmatic mice through the inhibition of NLRP3 inflammasome
Wenjuan Xu, Yimin Wang, Ying Ma, Jiong Yang
Targeted lung denervation in sheep: durability of denervation and long-term histologic effects on bronchial wall and peribronchial structures
Martin L. Mayse, Holly S. Norman, Alexander D. Peterson, Kristina T. Rouw, Philip J. Johnson
Statin use and lung cancer risk in chronic obstructive pulmonary disease patients: a population-based cohort study
AJN Raymakers, D. D. Sin, M. Sadatsafavi, JM FitzGerald, C. A. Marra, L. D. Lynd
Longitudinal functional changes with clinically significant radiographic progression in idiopathic pulmonary fibrosis: are we following the right parameters?
Nada Taha, Dejanira D’Amato, Karishma Hosein, Tiziana Ranalli, Gianluigi Sergiacomi, Maurizio Zompatori, Marco Mura
Cisplatin treatment induced interleukin 6 and 8 production alters lung adenocarcinoma cell migration in an oncogenic mutation dependent manner
Edit Kiss, El Husseiny Mohamed Mahmud Abdelwahab, Anita Steib, Emoke Papp, Zsofia Torok, Laszlo Jakab, Gabor Smuk, Veronika Sarosi, Judit Erzsebet Pongracz
Correction to: Inhibition of microRNA-451 is associated with increased expression of Macrophage Migration Inhibitory Factor and mitigation of the cardio-pulmonary phenotype in a murine model of Bronchopulmonary Dysplasia
Margaret Gilfillan, Pragnya Das, Dilip Shah, Mohammad Afaque Alam, Vineet Bhandari
Correction to: The ‘can do, do do’ concept in COPD; quadrant interpretation, affiliation and tracking longitudinal changes
Alex J. van ’t Hul, Noortje H. Koolen, Jeroen W. van Hees, Bram van den Borst, Martijn A. Spruit
IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters
Jinzhun Wu, Dandan Ge, Taoling Zhong, Zuojia Chen, Ying Zhou, Lingyun Hou, Xiaoliang Lin, Jiaxu Hong, Kuai Liu, Hui Qi, Chaoying Wang, Yulin Zhou, Cheng Li, Chuan Wu, Shuiping Wu, Zuguo Liu, Qiyuan Li
Automatization and improvement of μCT analysis for murine lung disease models using a deep learning approach
Gerald Birk, Marc Kästle, Cornelia Tilp, Birgit Stierstorfer, Stephan Klee
The pulmonary sequalae in discharged patients with COVID-19: a short-term observational study
Dehan Liu, Wanshu Zhang, Feng Pan, Lin Li, Lian Yang, Dandan Zheng, Jiazheng Wang, Bo Liang
Metabolomic fingerprinting and systemic inflammatory profiling of asthma COPD overlap (ACO)
Nilanjana Ghosh, Priyanka Choudhury, Sandeep Rai Kaushik, Rakesh Arya, Ranjan Nanda, Parthasarathi Bhattacharyya, Sushmita Roychowdhury, Rintu Banerjee, Koel Chaudhury
Risk stratification and prognostic factors in patients with pulmonary arterial hypertension and comorbidities a cross-sectional cohort study with survival follow-up
Panagiota Xanthouli, Maria Koegler, Alberto M. Marra, Nicola Benjamin, Lukas Fischer, Christina A. Eichstaedt, Satenik Harutyunova, Christian Nagel, Ekkehard Grünig, Benjamin Egenlauf
Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies
Fernando J. Martinez, Brian J. Lipworth, Klaus F. Rabe, David J. Collier, Gary T. Ferguson, Sanjay Sethi, Gregory J. Feldman, Gerald O’Brien, Martin Jenkins, Colin Reisner
Characterisation of microbiota in saliva, bronchoalveolar lavage fluid, non-malignant, peritumoural and tumour tissue in non-small cell lung cancer patients: a cross-sectional clinical trial
Rea Bingula, Edith Filaire, Ioana Molnar, Eve Delmas, Jean-Yves Berthon, Marie-Paule Vasson, Annick Bernalier-Donadille, Marc Filaire
SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation
Yanqi Wu, Yahui Wang, Bo Liu, Yumei Cheng, Hong Qian, Huilin Yang, Xiang Li, Guixia Yang, Xinghao Zheng, Feng Shen
Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials
Gary T. Ferguson, Nicola Brown, Chris Compton, Thomas C. Corbridge, Kelly Dorais, Charles Fogarty, Catherine Harvey, Morrys C. Kaisermann, David A. Lipson, Neil Martin, Frank Sciurba, Marjorie Stiegler, Chang-Qing Zhu, David Bernstein
TRIM72 promotes alveolar epithelial cell membrane repair and ameliorates lung fibrosis
Xiaofei Cong, Nagaraja Nagre, Jeremy Herrera, Andrew C. Pearson, Ian Pepper, Robell Morehouse, Hong-Long Ji, Dianhua Jiang, Rolf D. Hubmayr, Xiaoli Zhao
Quantitative CT-based structural alterations of segmental airways in cement dust-exposed subjects
Taewoo Kim, Hyun Bin Cho, Woo Jin Kim, Chang Hyun Lee, Kum Ju Chae, So-Hyun Choi, Kyeong Eun Lee, So Hyeon Bak, Sung Ok Kwon, Gong Yong Jin, Jiwoong Choi, Eun-Kee Park, Ching-Long Lin, Eric A. Hoffman, Sanghun Choi
Measuring disease activity in COPD: is clinically important deterioration the answer?
Dave Singh, Gerard J. Criner, Ian Naya, Paul W. Jones, Lee Tombs, David A. Lipson, MeiLan K. Han
Short-term effects of Lumacaftor/Ivacaftor (Orkambi™) on exertional symptoms, exercise performance, and ventilatory responses in adults with cystic fibrosis
Bradley S. Quon, Andrew H. Ramsook, Satvir S. Dhillon, Reid A. Mitchell, Kyle G. Boyle, Pearce G. Wilcox, Jordan A. Guenette
Influence of gender in monocrotaline and chronic hypoxia induced pulmonary hypertension in obese rats and mice
Balram Neupane, Akylbek Sydykov, Kabita Pradhan, Christina Vroom, Christiane Herden, Srikanth Karnati, Hossein Ardeschir Ghofrani, Sergey Avdeev, Süleyman Ergün, Ralph Theo Schermuly, Djuro Kosanovic
Local expression profiles of vitamin D-related genes in airways of COPD patients
Carolien Mathyssen, Celine Aelbrecht, Jef Serré, Stephanie Everaerts, Karen Maes, Ghislaine Gayan-Ramirez, Bart Vanaudenaerde, Wim Janssens
Predictive factors over time of health-related quality of life in COPD patients
Cristóbal Esteban, Inmaculada Arostegui, Amaia Aramburu, Javier Moraza, Josu Najera-Zuloaga, Myriam Aburto, Susana Aizpiri, Leyre Chasco, José M. Quintana
Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial
Nicola C. Day, Subramanya Kumar, Gerard Criner, Mark Dransfield, David M. G. Halpin, MeiLan K. Han, C. Elaine Jones, Morrys C. Kaisermann, Sally Kilbride, Peter Lange, David A. Lomas, Neil Martin, Fernando J. Martinez, Dave Singh, Robert Wise, David A. Lipson
Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway
Shangqin Chen, Qiuping Wu, Dingjuan Zhong, Changchong Li, Lizhong Du
Immunoreactivity to metal and silica associates with sarcoidosis in Dutch patients
E. Beijer, B. Meek, X. Bossuyt, S. Peters, R. C. H. Vermeulen, H. Kromhout, M. Veltkamp
Compared to plasma, bronchial washing fluid shows higher diagnostic yields for detecting EGFR-TKI sensitizing mutations by ddPCR in lung cancer
Sang Hoon Lee, Eun Young Kim, Taehee Kim, Yoon Soo Chang
Role of serum periostin in severe obstructive sleep apnea with albuminuria: an observational study
Hironobu Sunadome, Hisako Matsumoto, Ryo Tachikawa, Takeshi Matsumoto, Kiminobu Tanizawa, Toru Oga, Junya Ono, Shoichiro Ohta, Kenji Izuhara, Toyohiro Hirai, Kazuo Chin
Suppressed nuclear factor-kappa B alleviates lipopolysaccharide-induced acute lung injury through downregulation of CXCR4 mediated by microRNA-194
Ruidong Chen, Fei Xie, Jie Zhao, Bin Yue
Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis
Kakuhiro Yamaguchi, Hiroshi Iwamoto, Witold Mazur, Shinichiro Miura, Shinjiro Sakamoto, Yasushi Horimasu, Takeshi Masuda, Shintaro Miyamoto, Taku Nakashima, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori
Predictors of fatality including radiographic findings in adults with COVID-19
Kaiyan Li, Dian Chen, Shengchong Chen, Yuchen Feng, Chenli Chang, Zi Wang, Nan Wang, Guohua Zhen
Weighted Epworth sleepiness scale predicted the apnea-hypopnea index better
Qi Guo, Wei-dong Song, Wei Li, Chao Zeng, Yan-hong Li, Jian-ming Mo, Zhong-dong Lü, Mei Jiang
A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled corticosteroids
Edward Kerwin, Steven Pascoe, Zelie Bailes, Robert Nathan, David Bernstein, Ronald Dahl, Robyn von Maltzahn, Kevin Robbins, Andrew Fowler, Laurie Lee
CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial
Aili L. Lazaar, Bruce E. Miller, Alison C. Donald, Thomas Keeley, Claire Ambery, John Russell, Henrik Watz, Ruth Tal-Singer, Philip Bardin, Peter Bremner, David Langton, Anne-Marie Southcott, Paul S. Thomas, John Wheatley, Kenneth R. Chapman, Murdo Ferguson, Lawrence A. Homik, Francois Maltais, Bonavuth Pek, Eric St-Amour, Tamara Eckermann, Andreas Eich, Guido Ern, Karin Foerster, Andreas Forster, Martin Hoffmann, Claus Keller, Anneliese Linnhoff, Ruth Nischik, Isabelle Schenkenberger, Olaf Schmidt, Joong Hyun Ahn, Hee Soon Chung, Do-Jin Kim, Jae Yeol Kim, Sang Haak Lee, Yeon-Mok Oh, Myung Jae Park, Suk Joong Yong, Simone Van der Sar, Pascal L. M. L. Wielders, Anna Olech-Cudzik, Krzysztof Wytrychowski, Ghiulten Apti, Andreia Madalina Balta, Doru Didita, Livia Filip, Bogdan Mihai Mincu, Viorica Mincu, Roxana Maria Nemes, Maria Elena Scridon, Antigona Carmen Trofor, Dragos G. Ungurean, Ramon Agüero Balbín, Miguel Barrueco Ferrero, José Maria Echave-Sustaeta, José María Marín Trigo, Eduardo Monso Mola, Sergi Pascual Guardia, Germán Peces-Barba Romero, Roger A. Abrahams, Thomas M. Hyers, Edward M. Kerwin, Shawn M. Magee, Murali Ramaswamy, James Michael Wells
High flow nasal therapy during early pulmonary rehabilitation in patients with acute severe exacerbation of COPD: beneficial or illusory?
Guillaume Prieur, Yann Combret, Clement Medrinal
Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study
Huajun Xu, Chen Liang, Jianyin Zou, Hongliang Yi, Jian Guan, Meizhen Gu, Yanhong Feng, Shankai Yin
Trends and seasonal variation of hospitalization and mortality of interstitial lung disease in the United States from 2006 to 2016
An Thi Nhat Ho, Artem Shmelev, Edward Charbek
The impact of adjuvant surgical treatment of nontuberculous mycobacterial pulmonary disease on prognosis and outcome
Kiyoharu Fukushima, Mari Miki, Yuki Matsumoto, Emi Uda, Yuji Yamamoto, Yuya Kogita, Yuko Kagawa, Takanori Matsuki, Hiroyuki Kagawa, Yohei Oshitani, Daisuke Motooka, Kazuyuki Tsujino, Kenji Yoshimura, Keisuke Miki, Akio Hayashi, Shota Nakamura, Seigo Kitada, Yukiyasu Takeuchi, Hiroshi Kida
E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation
Qixin Wang, Isaac K. Sundar, Dongmei Li, Joseph H. Lucas, Thivanka Muthumalage, Samantha R. McDonough, Irfan Rahman
T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles
Elisabeth Ax, Zala Jevnikar, Aleksander Cvjetkovic, Carina Malmhäll, Henric Olsson, Madeleine Rådinger, Cecilia Lässer
Performance of brief ICF-sleep disorders and obesity core set in obstructive sleep apnea patients
Liang Xie, Qinhan Wu, Weiping Hu, Wenjing Li, Guiling Xiang, Shengyu Hao, Chengyao Guo, Hong Jiang, Xiaodan Wu, Xu Wu, Shanqun Li
Predictive factors of severe coronavirus disease 2019 in previously healthy young adults: a single-center, retrospective study
Changzhi Zhou, Zhe Huang, Weijun Tan, Xueying Li, Wen Yin, Yang Xiao, Zhaowu Tao, Shuang Geng, Yi Hu
Improving the evaluation of COPD exacerbation treatment effects by accounting for early treatment discontinuations: a post-hoc analysis of randomized clinical trials
Agnieszka Król, Robert Palmér, Virginie Rondeau, Stephen Rennard, Ulf G. Eriksson, Alexandra Jauhiainen
Adoption of a dedicated multidisciplinary team is associated with improved survival in acute pulmonary embolism
Lukasz A. Myc, Jigna N. Solanki, Andrew J. Barros, Nebil Nuradin, Matthew G. Nevulis, Kranthikiran Earasi, Emily D. Richardson, Shawn C. Tsutsui, Kyle B. Enfield, Nicholas R. Teman, Ziv J. Haskal, Sula Mazimba, Jamie L. W. Kennedy, Andrew D. Mihalek, Aditya M. Sharma, Alexandra Kadl
Host DNA released by NETosis in neutrophils exposed to seasonal H1N1 and highly pathogenic H5N1 influenza viruses
Louisa L. Y. Chan, John M. Nicholls, J. S. Malik Peiris, Yu Lung Lau, Michael C. W. Chan, Renee W. Y. Chan
RETRACTED ARTICLE: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production
Ya-nan Liu, Yan Guan, Jian Shen, Yong-liang Jia, Jian-cang Zhou, Yun Sun, Jun-xia Jiang, Hui-juan Shen, Qiang Shu, Qiang-min Xie, Yicheng Xie
Cardiac biomarkers of prognostic importance in chronic obstructive pulmonary disease
Ulf Nilsson, Nicholas L. Mills, David A. McAllister, Helena Backman, Caroline Stridsman, Linnea Hedman, Eva Rönmark, Takeshi Fujisawa, Anders Blomberg, Anne Lindberg
Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase
Yiying Huang, Cuiyan Tan, Jian Wu, Meizhu Chen, Zhenguo Wang, Liyun Luo, Xiaorong Zhou, Xinran Liu, Xiaoling Huang, Shican Yuan, Chaolin Chen, Fen Gao, Jin Huang, Hong Shan, Jing Liu
Acute exacerbations of COPD versus IPF in patients with combined pulmonary fibrosis and emphysema
Massa Zantah, Yaniv Dotan, Chandra Dass, Hauqing Zhao, Nathaniel Marchetti, Gerard J. Criner
Transcriptomic profiling reveals disease-specific characteristics of epithelial cells in idiopathic pulmonary fibrosis
Maximilian Boesch, Florent Baty, Martin H. Brutsche, Michael Tamm, Julien Roux, Lars Knudsen, Amiq Gazdhar, Thomas Geiser, Petra Khan, Katrin E. Hostettler
Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD
Mike Lonergan, Alison J. Dicker, Megan L. Crichton, Holly R. Keir, Melissa K. Van Dyke, Hana Mullerova, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers
CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis
Anna Birnhuber, Bakytbek Egemnazarov, Valentina Biasin, Ehsan Bonyadi Rad, Malgorzata Wygrecka, Horst Olschewski, Grazyna Kwapiszewska, Leigh M. Marsh
High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice
Shaza Abdulnasser Harfoush, Matthias Hannig, Duc Dung Le, Sebastian Heck, Maximilian Leitner, Albert Joachim Omlor, Isabella Tavernaro, Annette Kraegeloh, Ralf Kautenburger, Guido Kickelbick, Andreas Beilhack, Markus Bischoff, Juliane Nguyen, Martina Sester, Robert Bals, Quoc Thai Dinh
Dynamic changes of D-dimer and neutrophil-lymphocyte count ratio as prognostic biomarkers in COVID-19
Wenjing Ye, Guoxi Chen, Xiaopan Li, Xing Lan, Chen Ji, Min Hou, Di Zhang, Guangwang Zeng, Yaling Wang, Cheng Xu, Weiwei Lu, Ruolin Cui, Yuyang Cai, Hai Huang, Ling Yang
The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma
Jing Zhang, Zhenxing Zhu, Xu Zuo, He Pan, Yinuo Gu, Yuze Yuan, Guoqiang Wang, Shiji Wang, Ruipeng Zheng, Zhongmin Liu, Fang Wang, Jingtong Zheng
Clinical evaluation of potential usefulness of serum lactate dehydrogenase (LDH) in 2019 novel coronavirus (COVID-19) pneumonia
Mei-ying Wu, Lin Yao, Yi Wang, Xin-yun Zhu, Xia-fang Wang, Pei-jun Tang, Cheng Chen
Effect of hypertension on outcomes of adult inpatients with COVID-19 in Wuhan, China: a propensity score–matching analysis
Qing Yang, Ying Zhou, Xinrong Wang, Shan Gao, Yang Xiao, Weiming Zhang, Yi Hu, Yafei Wang
Airway-invasion-associated pulmonary computed tomography presentations characteristic of invasive pulmonary Aspergillosis in non-immunocompromised adults: a National Multicenter Retrospective Survey in China
Zhibo Liu, Yuping Li, Xinlun Tian, Qinghua Liu, Erran Li, Xiaoying Gu, Min Liu, Jiuyang Xu, Zhiyi He, Yi Huang, Shuyun Xu, Guoxiang Lai, Yusheng Chen, Xiangyan Zhang, Tiantuo Zhang, Jinfu Xu, Lanyan Zhu, Jieming Qu, Bin Cao
Early referral to palliative care in IPF – pitfalls and opportunities in clinical trials
Meena Kalluri, Elisabeth Bendstrup, Kathleen O. Lindell, Giovanni Ferrara
Extracellular vesicles: novel communicators in lung diseases
Aradhana Mohan, Stuti Agarwal, Matthias Clauss, Nicholas S. Britt, Navneet K. Dhillon
The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma
Giovanna Vella, Lars Lunding, Felix Ritzmann, Anja Honecker, Christian Herr, Michael Wegmann, Robert Bals, Christoph Beisswenger
Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial
Klaus F. Rabe, David M. G. Halpin, MeiLan K. Han, Marc Miravitlles, Dave Singh, Lars Grönke, Florian Voß, Fernando J. Martinez
The need for fast-track, high-quality and low-cost studies about the role of the BCG vaccine in the fight against COVID-19
Marcos Pereira, Enny Paixão, Anete Trajman, Ramon Andrade de Souza, Marcio Santos da Natividade, Julia M. Pescarini, Susan Martins Pereira, Florisneide Rodrigues Barreto, Ricardo Ximenes, Margareth Dalcomo, Maria Yury Ichihara, Ceuci Nunes, Manoel Barral-Netto, Maurício L. Barreto
Relationship between age and bronchodilator response at diagnosis in adult-onset asthma
Minna Tommola, Ha-Kyeong Won, Pinja Ilmarinen, Heewon Jung, Leena E. Tuomisto, Lauri Lehtimäki, Onni Niemelä, Tae-Bum Kim, Hannu Kankaanranta
Relationship of chest CT score with clinical characteristics of 108 patients hospitalized with COVID-19 in Wuhan, China
Jie Zhang, Guangping Meng, Wei Li, Bingqing Shi, Hongna Dong, Zhenzhong Su, Qian Huang, Peng Gao
Nasal microbiota dominated by Moraxella spp. is associated with respiratory health in the elderly population: a case control study
Ellen H. A. van den Munckhof, Harriet C. Hafkamp, Josephine de Kluijver, Ed J. Kuijper, Maurits N. C. de Koning, Wim G. V. Quint, Cornelis W. Knetsch
SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis
Jincheng Xu, Xiaoyue Xu, Lina Jiang, Kamal Dua, Philip M. Hansbro, Gang Liu
The sputum microbiome is distinct between COPD and health, independent of smoking history
Koirobi Haldar, Leena George, Zhang Wang, Vijay Mistry, Mohammadali Yavari Ramsheh, Robert C. Free, Catherine John, Nicola F. Reeve, Bruce E. Miller, Ruth Tal-Singer, Adam J. Webb, Anthony J. Brookes, Martin D. Tobin, Dave Singh, Gavin C. Donaldson, Jadwiga A. Wedzicha, James R. Brown, Michael R. Barer, Christopher E. Brightling
A novel pleural-bladder pump for the management of recurrent malignant pleural effusions: a feasibility animal study
S. Laroumagne, J. Guinde, S. Berdah, H. Dutau, J. Capel, P. Astoul
The association between pulmonary embolism and the cancer-related genomic alterations in patients with NSCLC
Wei Xiong, He Du, Wei Ding, Jinyuan Sun, Mei Xu, Xuejun Guo
In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression
Hélène Le Ribeuz, Audrey Courboulin, Maria-Rosa Ghigna, Mélanie Lambert, Aurélie Hautefort, Marc Humbert, David Montani, Sylvia Cohen-Kaminsky, Frédéric Perros, Fabrice Antigny
ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction
Xiaoyun Wang, Duo Zhang, Andrew Higham, Sophie Wolosianka, Xiaoyan Gai, Lu Zhou, Hans Petersen, Victor Pinto-Plata, Miguel Divo, Edwin K. Silverman, Bartolome Celli, Dave Singh, Yongchang Sun, Caroline A. Owen
Possible reversibility between epithelioid and sarcomatoid types of mesothelioma is independent of ERC/mesothelin expression
Masataka Kojima, Kazunori Kajino, Shuji Momose, Nadila Wali, May Thinzar Hlaing, Bo Han, Liang Yue, Masaaki Abe, Tomoaki Fujii, Katsuhisa Ikeda, Okio Hino
Assessment of comorbidities and prognosis in patients with COPD diagnosed with the fixed ratio and the lower limit of normal: a systematic review and meta-analysis
Huaiyu Xiong, Qiangru Huang, Tiankui Shuai, Lei Zhu, Chuchu Zhang, Meng Zhang, Yalei Wang, Jian Liu
The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia
Saira Ahmad, Christine Seul Ki Kim, Robert Tarran
Investigation of occurrence patterns of respiratory syncytial virus A and B in infected-patients from Cheonan, Korea
Ga-Yeon Kim, Insoo Rheem, You Hyun Joung, Jae Kyung Kim
Cold-inducible RNA-binding protein might determine the severity and the presences of major/minor criteria for severe community-acquired pneumonia and best predicted mortality
Qi Guo, Wei-dong Song, Hai-yan Li, Ming Li, Xiao-ke Chen, Hui Liu, Hong-lin Peng, Hai-qiong Yu, Nian Liu, Zhong-dong Lü, Li-hua Liang, Qing-zhou Zhao, Mei Jiang
LPS aggravates lung inflammation induced by RSV by promoting the ERK-MMP-12 signaling pathway in mice
Shenglin Chen, Jun Xie, Keting Zhao, Luo Ren, Yu Deng, Xiaohong Xie, Shiyi Chen, Hongmei Xu, Xiaoru Long, Enmei Liu
Continuously available ratio of SpO2/FiO2 serves as a noninvasive prognostic marker for intensive care patients with COVID-19
Xiaofan Lu, Liyun Jiang, Taige Chen, Yang Wang, Bing Zhang, Yizhou Hong, Jun Wang, Fangrong Yan
Palliation of chronic breathlessness with morphine in patients with fibrotic interstitial lung disease – a randomised placebo-controlled trial
Sissel Kronborg-White, Charlotte Uggerhøj Andersen, Charlotte Kohberg, Ole Hilberg, Elisabeth Bendstrup
Patient expectations, experiences and satisfaction with nintedanib and pirfenidone in idiopathic pulmonary fibrosis: a quantitative study
C. C. Moor, R. L. M. Mostard, J. C. Grutters, P. Bresser, J. G. J. V. Aerts, C. D. Dirksen, M. L. Kimman, M. S. Wijsenbeek
The need for a holistic approach for SSc-ILD – achievements and ambiguity in a devastating disease
Anna-Maria Hoffmann-Vold, Yannick Allanore, Elisabeth Bendstrup, Cosimo Bruni, Oliver Distler, Toby M. Maher, Marlies Wijsenbeek, Michael Kreuter
The pathophysiology of ‘happy’ hypoxemia in COVID-19
Sebastiaan Dhont, Eric Derom, Eva Van Braeckel, Pieter Depuydt, Bart N. Lambrecht
Tiotropium in chronic obstructive pulmonary disease – a review of clinical development
Antonio Anzueto, Marc Miravitlles
Cell-specific expression of lung disease risk-related genes in the human small airway epithelium
Wu-lin Zuo, Mahboubeh R. Rostami, Shushila A. Shenoy, Michelle G. LeBlanc, Jacqueline Salit, Yael Strulovici-Barel, Sarah L. O’Beirne, Robert J. Kaner, Philip L. Leopold, Jason G. Mezey, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
Association between cytokine profiles and lung injury in COVID-19 pneumonia
Li-Da Chen, Zhen-Yu Zhang, Xiao-Jie Wei, Yu-Qing Cai, Weng-Zhen Yao, Ming-Hui Wang, Qiu-Fen Huang, Xiao-Bin Zhang
Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
Sarah R. Rønnow, Lasse L. Langholm, Morten A. Karsdal, Tina Manon-Jensen, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana J. Leeming, Jannie M. B. Sand
Impact of gastroesophageal reflux on longitudinal lung function and quantitative computed tomography in the COPDGene cohort
Arianne K. Baldomero, Chris H. Wendt, Ashley Petersen, Nathaniel T. Gaeckle, MeiLan K. Han, Ken M. Kunisaki
Pregnancy-associated plasma protein A – a new indicator of pulmonary vascular remodeling in chronic thromboembolic pulmonary hypertension?
Steffen D. Kriechbaum, Felix Rudolph, Christoph B. Wiedenroth, Lisa Mielzarek, Moritz Haas, Stefan Guth, Christian W. Hamm, Eckhard Mayer, Christoph Liebetrau, Till Keller
Analysis of serum polyunsaturated fatty acid metabolites in allergic bronchopulmonary aspergillosis
Lu Li, Jianlin Wu, Xiqing Bian, Ge Wu, Peiyan Zheng, Mingshan Xue, Baoqing Sun
Mechanisms affecting exercise ventilatory inefficiency-airflow obstruction relationship in male patients with chronic obstructive pulmonary disease
Ming-Lung Chuang
Sonic hedgehog signalling as a potential endobronchial biomarker in COPD
Julien Ancel, Randa Belgacemi, Jeanne-Marie Perotin, Zania Diabasana, Sandra Dury, Maxime Dewolf, Arnaud Bonnomet, Nathalie Lalun, Philippe Birembaut, Myriam Polette, Gaëtan Deslée, Valérian Dormoy
Functional glutamate transporters are expressed in the carotid chemoreceptor
Chaohong Li, Lu Huang, Xianglei Jia, Baosheng Zhao, Lingyun Chen, Yuzhen Liu
A comparison of four different models of acute respiratory distress syndrome in sheep
Monique Engel, Relana M. E. Nowacki, Elly M. Jonker, Daan Ophelders, Maria Nikiforou, Nico Kloosterboer, Luc J. I. Zimmermann, Dick A. van Waardenburg, Boris W. Kramer
FGL1 regulates acquired resistance to Gefitinib by inhibiting apoptosis in non-small cell lung cancer
Cuilan Sun, Weiwei Gao, Jiatao Liu, Hao Cheng, Jiqing Hao
Correction to: Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study
A. M. Fratta Pasini, C. Stranieri, M. Ferrari, U. Garbin, L. Cazzoletti, C. Mozzini, F. Spelta, D. Peserico, L. Cominacini
Chronic oral corticosteroids use and persistent eosinophilia in severe asthmatics from the Belgian severe asthma registry
S. Graff, S. Vanwynsberghe, G. Brusselle, S. Hanon, C. Sohy, L. J. Dupont, R. Peche, A. Michils, C. Pilette, G. Joos, R. E. Louis, F. N. Schleich
HGF alleviates septic endothelial injury by inhibiting pyroptosis via the mTOR signalling pathway
Fei Peng, Wei Chang, Qin Sun, Xinyi Xu, Jianfeng Xie, Haibo Qiu, Yi Yang
Fortified whey beverage for improving muscle mass in chronic obstructive pulmonary disease: a single-blind, randomized clinical trial
Afsane Ahmadi, Mohammad Hassan Eftekhari, Zohreh Mazloom, Masoom Masoompour, Mohammad Fararooei, Mohammad Hadi Eskandari, Samrad Mehrabi, Alireza Bedeltavana, Mandana Famouri, Morteza Zare, Nasrin Nasimi, Zahra Sohrabi
Outcome measures for airway clearance techniques in children with chronic obstructive lung diseases: a systematic review
Eline Lauwers, Kris Ides, Kim Van Hoorenbeeck, Stijn Verhulst
An authoritative algorithm most appropriate for the prediction of pulmonary embolism in patients with AECOPD
Wei Xiong, He Du, Mei Xu, Wei Ding, Jinyuan Sun, Fengfeng Han, Xuejun Guo
Cluster analysis in 975 patients with current cough identifies a phenotype with several cough triggers, many background disorders, and low quality of life
Heikki O. Koskela, Tuomas A. Selander, Anne M. Lätti
Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study
Julia Sanchez, Desiree M. Schumann, Meropi Karakioulaki, Eleni Papakonstantinou, Frank Rassouli, Matthias Frasnelli, Martin Brutsche, Michael Tamm, Daiana Stolz
CXCR4+ cells are increased in lung tissue of patients with idiopathic pulmonary fibrosis
Jade Jaffar, Kate Griffiths, Sara Oveissi, Mubing Duan, Michael Foley, Ian Glaspole, Karen Symons, Louise Organ, Glen Westall
Flagellin shifts 3D bronchospheres towards mucus hyperproduction
Richard F. Sprott, Felix Ritzmann, Frank Langer, Yiwen Yao, Christian Herr, Yvonne Kohl, Thomas Tschernig, Robert Bals, Christoph Beisswenger
The effects of anti-inflammatory agents as host-directed adjunct treatment of tuberculosis in humans: a systematic review and meta-analysis
Frank Ekow Atta Hayford, Robin Claire Dolman, Renee Blaauw, Arista Nienaber, Cornelius Mattheus Smuts, Linda Malan, Cristian Ricci
From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses
Zhixing Zhu, Xihua Lian, Xiaoshan Su, Weijing Wu, Giuseppe A. Marraro, Yiming Zeng
Maternal and infant outcomes in sarcoidosis pregnancy: a Swedish population-based cohort study of first births
Laura Köcher, Marios Rossides, Katarina Remaeus, Johan Grunewald, Anders Eklund, Susanna Kullberg, Elizabeth V. Arkema
A retrospective analysis of usefulness of impulse oscillometry system in the treatment of asthma
Hiroyuki Sugawara, Atsushi Saito, Saori Yokoyama, Kazunori Tsunematsu, Hirofumi Chiba, Hiroki Takahashi
AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma
Ting Liu, Jianjie Zhu, Wenwen Du, Weiwei Ning, Yang Zhang, Yuanyuan Zeng, Zeyi Liu, Jian-An Huang
Value of metalloproteinases in predicting COPD in heavy urban smokers
Jun-Chieh J. Tsay, Yingjie Hu, Judith D. Goldberg, Bin Wang, Soumya Vijayalekshmy, Ting-An Yie, Katrina Bantis, Daniel H. Sterman, William N. Rom
Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model
Huihui Zeng, Tiao Li, Xue He, Shan Cai, Hong Luo, Ping Chen, Yan Chen
Effect of maternal sleep, physical activity and screen time during pregnancy on the risk of childhood respiratory allergies: a sex-specific study
Yiting Chen, Jiajun Lyu, Yuanqing Xia, Jianzhen Zhu, Shilu Tong, Yong Ying, Jiajie Qu, Shenghui Li
Usefulness of surgical lung biopsies after cryobiopsies when pathological results are inconclusive or show a pattern suggestive of a nonspecific interstitial pneumonia
Benjamin Bondue, Dimitri Leduc, Antoine Froidure, Thierry Pieters, Olivier Taton, Vincent Heinen, Patrick Alexander, Delphine Hoton, Florence Dome, Myriam Remmelink
Nrf2 protects against seawater drowning-induced acute lung injury via inhibiting ferroptosis
Yu-bao Qiu, Bin-bin Wan, Gang Liu, Ya-xian Wu, Dan Chen, Mu-dan Lu, Jun-liang Chen, Ren-qiang Yu, Dao-zhen Chen, Qing-feng Pang
Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responses
Jon Petur Joelsson, Jennifer A. Kricker, Ari J. Arason, Snaevar Sigurdsson, Bryndis Valdimarsdottir, Fridrik Runar Gardarsson, Clive P. Page, Fredrik Lehmann, Thorarinn Gudjonsson, Saevar Ingthorsson
Presence of heat shock protein 47-positive fibroblasts in cancer stroma is associated with increased risk of postoperative recurrence in patients with lung cancer
Takuto Miyamura, Noriho Sakamoto, Kaori Ishida, Tomoyuki Kakugawa, Hirokazu Taniguchi, Yoshiko Akiyama, Daisuke Okuno, Atsuko Hara, Takashi Kido, Hiroshi Ishimoto, Takuro Miyazaki, Keitaro Matsumoto, Tomoshi Tsuchiya, Hiroyuki Yamaguchi, Taiga Miyazaki, Yasushi Obase, Yuji Ishimatsu, Takeshi Nagayasu, Hiroshi Mukae
LINC01503/miR-342-3p facilitates malignancy in non-small-cell lung cancer cells via regulating LASP1
Qiming Shen, Yanbin Sun, Shun Xu
Pneumothorax in COVID-19 disease- incidence and clinical characteristics
Massa Zantah, Eduardo Dominguez Castillo, Ryan Townsend, Fusun Dikengil, Gerard J. Criner
Pentraxin 3 promotes airway inflammation in experimental asthma
Pengfei Gao, Kun Tang, Yanjiao Lu, Zhenli Huang, Shanshan Wang, Meijia Wang, Jianmiao Wang, Jianping Zhao, Jungang Xie
Influence of obesity on remodeling of lung tissue and organization of extracellular matrix after blunt thorax trauma
Pengfei Xu, Fabian Gärtner, Adrian Gihring, Congxing Liu, Timo Burster, Martin Wabitsch, Uwe Knippschild, Stephan Paschke
Smoking-associated increase in mucins 1 and 4 in human airways
Heta Merikallio, Riitta Kaarteenaho, Sara Lindén, Médea Padra, Reza Karimi, Chuan-Xing Li, Elisa Lappi-Blanco, Åsa M. Wheelock, Magnus C. Sköld
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
Dave Singh, Jadwiga A. Wedzicha, Salman Siddiqui, Alberto de la Hoz, Wenqiong Xue, Helgo Magnussen, Marc Miravitlles, James D. Chalmers, Peter M. A. Calverley
The effect of vascular risk factor burden on the severity of COVID-19 illness, a retrospective cohort study
Houwei Du, Xiaobin Pan, Nan Liu, Junnian Chen, Xiaoling Chen, David J. Werring, Gareth Ambler, Xiaoqing Li, Ronghua Chen, Yixian Zhang, Huayao Huang, Feifei Lin, Pincang Xia, Chao Chen, Zhenyang Zheng, Sangru Wu, Hanhan Lei, Lei Gao, Mingxu Huang, Kexu Lin, Xiaoping Xu, Yukun Luo, Ziwen Zhao, Chen Li, Hailong Lin, Yu Lin, Zhenghui Huang, Rongxiang Cao, Limin Chen
Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease
Ding Liu, Maureen Meister, Shiying Zhang, Chi-In Vong, Shuaishuai Wang, Ruixie Fang, Lei Li, Peng George Wang, Pierre Massion, Xiangming Ji
Patterns of adaptive servo-ventilation settings in a real-life multicenter study: pay attention to volume!
Dany Jaffuel, Claudio Rabec, Carole Philippe, Jean-Pierre Mallet, Marjolaine Georges, Stefania Redolfi, Alain Palot, Carey M. Suehs, Erika Nogue, Nicolas Molinari, Arnaud Bourdin
Airway nitrite is increased in extremely preterm infants with bronchopulmonary dysplasia
Samuel J. Gentle, Amelia Freeman, Rakesh P. Patel, Namasivayam Ambalavanan, Charitharth V. Lal
Inflammatory phenotyping predicts clinical outcome in COVID-19
H. Burke, A. Freeman, D. C. Cellura, B. L. Stuart, N. J. Brendish, S. Poole, F. Borca, H. T. T. Phan, N. Sheard, S. Williams, C. M. Spalluto, K. J. Staples, T. W. Clark, T. M. A. Wilkinson, Tom Wilkinson, Anna Freeman, Hannah Burke, Ahilanadan Dushianthan, Michael Celinski, James Batchelor, Saul N. Faust, Gareth Thomas, Christopher Kipps
Efficacy and safety of CHF6001, a novel inhaled PDE4 inhibitor in COPD: the PIONEER study
Dave Singh, Aida Emirova, Catherine Francisco, Debora Santoro, Mirco Govoni, Marie Anna Nandeuil
Long-term exposure to PM10 and NO2 in relation to lung function and imaging phenotypes in a COPD cohort
Sung Ok Kwon, Seok Ho Hong, Young-Ji Han, So Hyeon Bak, Junghyun Kim, Mi Kyeong Lee, Stephanie J. London, Woo Jin Kim, Sun-Young Kim
Lung function, pharmacokinetics, and tolerability of inhaled indacaterol maleate and acetate in asthma patients
David Miller, Soniya Vaidya, Juergen Jauernig, Brian Ethell, Kristina Wagner, Rajkumar Radhakrishnan, Hanns-Christian Tillmann
Misconceptions of pathophysiology of happy hypoxemia and implications for management of COVID-19
Martin J. Tobin, Amal Jubran, Franco Laghi
Regulation of ATP binding cassette transporter A1 (ABCA1) expression: cholesterol-dependent and – independent signaling pathways with relevance to inflammatory lung disease
Patrick He, Ingrid C. Gelissen, Alaina J. Ammit
Association of diurnal temperature range with daily hospitalization for exacerbation of chronic respiratory diseases in 21 cities, China
Zihui Wang, Yumin Zhou, Ming Luo, Huajing Yang, Shan Xiao, Xiaoliang Huang, Yubo Ou, Yongbo Zhang, Xianzhong Duan, Wei Hu, Chenghao Liao, Yijia Zheng, Long Wang, Min Xie, Longhui Tang, Jinzhen Zheng, Sha Liu, Fan Wu, Zhishan Deng, Heshen Tian, Jieqi Peng, Xinwang Wang, Nanshan Zhong, Pixin Ran
Expression of SARS-CoV-2 entry receptors in the respiratory tract of healthy individuals, smokers and asthmatics
Magdalena Matusiak, Christian M. Schürch
Artificial intelligence accuracy in detecting pathological breath sounds in children using digital stethoscopes
Ajay Kevat, Anaath Kalirajah, Robert Roseby
Quantitative CT-based image registration metrics provide different ventilation and lung motion patterns in prone and supine positions in healthy subjects
Kyung Min Shin, Jiwoong Choi, Kum Ju Chae, Gong Yong Jin, Ali Eskandari, Eric A. Hoffman, Chase Hall, Mario Castro, Chang Hyun Lee
Procalcitonin and lung ultrasound algorithm to diagnose severe pneumonia in critical paediatric patients (PROLUSP study). A randomised clinical trial
Javier Rodríguez-Fanjul, Carmina Guitart, Sara Bobillo-Perez, Mònica Balaguer, Iolanda Jordan
Dexamethasone rescues TGF-β1-mediated β2-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells
Elena Chung, Christie A. Ojiaku, Gaoyuan Cao, Vishal Parikh, Brian Deeney, Shengjie Xu, Serena Wang, Reynold A. Panettieri Jr, Cynthia Koziol-White
Epidemiological characteristics and the entire evolution of coronavirus disease 2019 in Wuhan, China
Dongming Wang, Jing Cai, Tingming Shi, Yang Xiao, Xiaobing Feng, Meng Yang, Wenzhen Li, Wei Liu, Linling Yu, Zi Ye, Tao Xu, Jixuan Ma, Mingyan Li, Weihong Chen
Obstructive sleep apnea as a risk factor for primary open angle glaucoma and ocular hypertension in a monocentric pilot study
Katharina Bahr, Michael Bopp, Waeel Kewader, Henri Dootz, Julia Döge, Tilman Huppertz, Perikles Simon, Verena Prokosch-Willing, Christoph Matthias, Haralampos Gouveris
Functional analysis and evaluation of respiratory cilia in healthy Chinese children
So-Lun Lee, Christopher O’Callaghan, Yu-Lung Lau, Chun-Wai Davy Lee
COVID-19 multidisciplinary high dependency unit: the Milan model
Stefano Aliberti, Francesco Amati, Maria Pappalettera, Marta Di Pasquale, Alice D’Adda, Marco Mantero, Andrea Gramegna, Edoardo Simonetta, Anna Maria Oneta, Emilia Privitera, Andrea Gori, Giorgio Bozzi, Flora Peyvandi, Francesca Minoia, Giovanni Filocamo, Chiara Abbruzzese, Marco Vicenzi, Paola Tagliabue, Salvatore Alongi, Francesco Blasi
Hypoxemia in COVID-19: cerebral oximetry should be explored as a warning indicator for mechanically ventilated adults with COVID-19
Marco Ferrari, Valentina Quaresima
Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease
Gulam Haji, Coen H. Wiegman, Charalambos Michaeloudes, Mehul S. Patel, Katrina Curtis, Pankaj Bhavsar, Michael I. Polkey, Ian M. Adcock, Kian Fan Chung
Bone turnover biomarkers in COPD patients randomized to either a regular or shortened course of corticosteroids: a substudy of the randomized controlled CORTICO-COP trial
Pradeesh Sivapalan, Niklas R. Jørgensen, Alexander G. Mathioudakis, Josefin Eklöf, Therese Lapperre, Charlotte Suppli Ulrik, Helle F. Andreassen, Karin Armbruster, Praleene Sivapalan, Julie Janner, Nina Godtfredsen, Ulla M. Weinreich, Thyge L. Nielsen, Niels Seersholm, Torgny Wilcke, Philipp Schuetz, Tobias W. Klausen, Kristoffer Marså, Jørgen Vestbo, Jens-Ulrik Jensen
SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma
Michael E. Wechsler, Gene Colice, Janet M. Griffiths, Gun Almqvist, Tor Skärby, Teresa Piechowiak, Primal Kaur, Karin Bowen, Åsa Hellqvist, May Mo, Esther Garcia Gil
CASCADE: a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of tezepelumab on airway inflammation in patients with uncontrolled asthma
Claire Emson, Sarah Diver, Latifa Chachi, Ayman Megally, Cherrie Small, John Downie, Jane R. Parnes, Karin Bowen, Gene Colice, Chris E. Brightling
NAVIGATOR: a phase 3 multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of tezepelumab in adults and adolescents with severe, uncontrolled asthma
Andrew Menzies-Gow, Gene Colice, Janet M. Griffiths, Gun Almqvist, Sandhia Ponnarambil, Primal Kaur, Gennaro Ruberto, Karin Bowen, Åsa Hellqvist, May Mo, Esther Garcia Gil
Dyspnea, effort and muscle pain during exercise in lung transplant recipients: an analysis of their association with cardiopulmonary function parameters using machine learning
Fausto Braccioni, Daniele Bottigliengo, Andrea Ermolao, Marco Schiavon, Monica Loy, Maria Rita Marchi, Dario Gregori, Federico Rea, Andrea Vianello
Unmet need in severe, uncontrolled asthma: can anti-TSLP therapy with tezepelumab provide a valuable new treatment option?
Andrew Menzies-Gow, Michael E. Wechsler, Chris E. Brightling
Cell-specific toxicity of short-term JUUL aerosol exposure to human bronchial epithelial cells and murine macrophages exposed at the air–liquid interface
Rakeysha Pinkston, Hasan Zaman, Ekhtear Hossain, Arthur L. Penn, Alexandra Noël
Variability of forced vital capacity in progressive interstitial lung disease: a prospective observational study
Tobias Veit, Michaela Barnikel, Alexander Crispin, Nikolaus Kneidinger, Felix Ceelen, Paola Arnold, Dieter Munker, Magdalena Schmitzer, Jürgen Barton, Sanziana Schiopu, Herbert B. Schiller, Marion Frankenberger, Katrin Milger, Jürgen Behr, Claus Neurohr, Gabriela Leuschner
Chronic exposure to ambient particulate matter induces gut microbial dysbiosis in a rat COPD model
Naijian Li, Zhaowei Yang, Baoling Liao, Tianhui Pan, Jinding Pu, Binwei Hao, Zhenli Fu, Weitao Cao, Yuming Zhou, Fang He, Bing Li, Pixin Ran
Upper airway lengthening caused by weight increase in obstructive sleep apnea patients
Hongyi Lin, Huahui Xiong, Changjin Ji, Cunting Wang, Yong Li, Yunqiang An, Geng Li, Jianggui Guo, Xiaoqing Huang, Han Zhang, Hong Liu, Ting Li, Zheng Li, Junfang Xian, Yaqi Huang
Long-term clinical course and outcomes of immunoglobulin G4-related lung disease
Jieun Kang, Shinhee Park, Eun Jin Chae, Joon Seon Song, Hee Sang Hwang, Sun Jong Kim, Tae Jun Song, Myung-Whan Kim, Jin Woo Song
Exploration of the sputum methylome and omics deconvolution by quadratic programming in molecular profiling of asthma and COPD: the road to sputum omics 2.0
Espen E. Groth, Melanie Weber, Thomas Bahmer, Frauke Pedersen, Anne Kirsten, Daniela Börnigen, Klaus F. Rabe, Henrik Watz, Ole Ammerpohl, Torsten Goldmann
Automated computed tomography quantification of fibrosis predicts prognosis in combined pulmonary fibrosis and emphysema in a real-world setting: a single-centre, retrospective study
Masahiro Nemoto, Yuichiro Nei, Brian Bartholmai, Kazuki Yoshida, Hiroki Matsui, Tamao Nakashita, Shinji Motojima, Masahiro Aoshima, Jay H. Ryu
Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study
Thomas Sonnweber, Anna Boehm, Sabina Sahanic, Alex Pizzini, Magdalena Aichner, Bettina Sonnweber, Katharina Kurz, Sabine Koppelstätter, David Haschka, Verena Petzer, Richard Hilbe, Markus Theurl, Daniela Lehner, Manfred Nairz, Bernhard Puchner, Anna Luger, Christoph Schwabl, Rosa Bellmann-Weiler, Ewald Wöll, Gerlig Widmann, Ivan Tancevski, Judith-Löffler-Ragg, Günter Weiss
Risk factors for the critical illness in SARS-CoV-2 infection: a multicenter retrospective cohort study
Sijing Cheng, Dingfeng Wu, Jie Li, Yifeng Zou, Yunle Wan, Lihan Shen, Lixin Zhu, Mang Shi, Linlin Hou, Tao Xu, Na Jiao, Yichen Li, Yibo Huang, Zhipeng Tang, Mingwei Xu, Shusong Jiang, Maokun Li, Guangjun Yan, Ping Lan, Ruixin Zhu
Small airway dysfunction as predictor and marker for clinical response to biological therapy in severe eosinophilic asthma: a longitudinal observational study
Mustafa Abdo, Henrik Watz, Vera Veith, Anne-Marie Kirsten, Heike Biller, Frauke Pedersen, Erika von Mutius, Matthias V. Kopp, Gesine Hansen, Benjamin Waschki, Klaus F. Rabe, Frederik Trinkmann, Thomas Bahmer
DESTINATION: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the long-term safety and tolerability of tezepelumab in adults and adolescents with severe, uncontrolled asthma
Andrew Menzies-Gow, Sandhia Ponnarambil, John Downie, Karin Bowen, Åsa Hellqvist, Gene Colice
Salbutamol use in relation to maintenance bronchodilator efficacy in COPD: a prospective subgroup analysis of the EMAX trial
F. Maltais, I. P. Naya, C. F. Vogelmeier, I. H. Boucot, P. W. Jones, L. Bjermer, L. Tombs, C. Compton, D. A. Lipson, E. M. Kerwin
Thoracentesis under clopidogrel is not associated with excessive bleeding events: a cohort study
Sivan Perl, Marina Bondarenco, Noam Natif, Yitschak Shpirer, Sharon Enghelberg, Benjamin Fox
Influenza A virus enhances ciliary activity and mucociliary clearance via TLR3 in airway epithelium
Yosuke Kamiya, Tomoyuki Fujisawa, Mineo Katsumata, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Mitsutoshi Setou, Masahiko Ito, Tetsuro Suzuki, Koji Ikegami, Takafumi Suda
Decreased COPD prevalence in Sweden after decades of decrease in smoking
Helena Backman, Lowie Vanfleteren, Anne Lindberg, Linda Ekerljung, Caroline Stridsman, Malin Axelsson, Ulf Nilsson, Bright I. Nwaru, Sami Sawalha, Berne Eriksson, Linnea Hedman, Madeleine Rådinger, Sven-Arne Jansson, Anders Ullman, Hannu Kankaanranta, Jan Lötvall, Eva Rönmark, Bo Lundbäck
Auxiliary diagnostic value of tumor biomarkers in pleural fluid for lung cancer-associated malignant pleural effusion
Hai Zhang, Changhui Li, Fang Hu, Xueyan Zhang, Yinchen Shen, Yuqing Chen, Feng Li
Determinants of response to inhaled extrafine triple therapy in asthma: analyses of TRIMARAN and TRIGGER
Dave Singh, Johann Christian Virchow, Giorgio Walter Canonica, Andrea Vele, Maxim Kots, George Georges, Alberto Papi
Are there pulmonary sequelae in patients recovering from COVID-19?
Paola Rogliani, Luigino Calzetta, Angelo Coppola, Ermanno Puxeddu, Gianluigi Sergiacomi, Dejanira D’Amato, Antonio Orlacchio
Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells
Huan Liu, Qian Cheng, Dong-sheng Xu, Wen Wang, Zheng Fang, Dong-dong Xue, Ya Zheng, Alex H. Chang, Yan-jun Lei
Physiologically variable ventilation reduces regional lung inflammation in a pediatric model of acute respiratory distress syndrome
Andre Dos Santos Rocha, Gergely H. Fodor, Miklos Kassai, Loic Degrugilliers, Sam Bayat, Ferenc Petak, Walid Habre
Bacteria and sputum inflammatory cell counts; a COPD cohort analysis
Augusta S. Beech, Simon Lea, Umme Kolsum, Zhang Wang, Bruce E. Miller, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling, Dave Singh
Long non-coding RNA H19 deficiency ameliorates bleomycin-induced pulmonary inflammation and fibrosis
Xiaoyu Wan, Xinbei Tian, Jun Du, Ying Lu, Yongtao Xiao
The relationship between body mass index and health-related quality of life in COPD: real-world evidence based on claims and survey data
Manuel B. Huber, Christoph Kurz, Florian Kirsch, Larissa Schwarzkopf, Anja Schramm, Reiner Leidl
Non-linear association between diabetes mellitus and pulmonary function: a population-based study
Rui-Heng Zhang, Jian-Bo Zhou, Yao-Hua Cai, Lin-Ping Shu, Rafael Simó, Albert Lecube
The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation and puncture (CLP) in mice
Liu Yang, Sijie Liu, Silu Han, Yuhan Hu, Zhipeng Wu, Xiaoqian Shi, Baosen Pang, Yingmin Ma, Jiawei Jin
The association between serum vitamin D and obstructive sleep apnea: an updated meta-analysis
Xiaoyan Li, Jie He, Jie Yun
Computed tomography patterns predict clinical course of idiopathic pulmonary fibrosis
Byoung Soo Kwon, Jooae Choe, Kyung Hyun Do, Hee Sang Hwang, Eun Jin Chae, Jin Woo Song
Additional work of breathing from trigger errors in mechanically ventilated children
Robert G. T. Blokpoel, Alette A. Koopman, Jefta van Dijk, Martin C. J. Kneyber
Pain is a common problem in patients with ILD
Qinxue Shen, Ting Guo, Min Song, Wei Guo, Yi Zhang, Wang Duan, Yating Peng, Shanshan Ni, Xiaoli Ouyang, Hong Peng
Association between serum calcium and prognosis in patients with acute pulmonary embolism and the optimization of pulmonary embolism severity index
Xin Wang, Yongbo Xiang, Ting Zhang, Yuqing Yang, Xuefeng Sun, Juhong Shi
Potential role of polycyclic aromatic hydrocarbons in air pollution-induced non-malignant respiratory diseases
Marit Låg, Johan Øvrevik, Magne Refsnes, Jørn A. Holme
Use of electronic cigarettes and secondhand exposure to their aerosols are associated with asthma symptoms among adolescents: a cross-sectional study
Abdullah Alnajem, Abdullah Redha, Dalal Alroumi, Ahmed Alshammasi, Mohamad Ali, Maram Alhussaini, Waad Almutairi, Ali Esmaeil, Ali H. Ziyab
Effect of nocturnal EPAP titration to abolish tidal expiratory flow limitation in COPD patients with chronic hypercapnia: a randomized, cross-over pilot study
Emanuela Zannin, Ilaria Milesi, Roberto Porta, Simona Cacciatore, Luca Barbano, R. Trentin, Francesco Fanfulla, Michele Vitacca, Raffaele L. Dellacà
ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
Ana N. Gonçalves, Jorge Correia-Pinto, Cristina Nogueira-Silva
Pulmonary hypertension secondary to pulmonary fibrosis: clinical data, histopathology and molecular insights
Grégoire Ruffenach, Jason Hong, Mylène Vaillancourt, Lejla Medzikovic, Mansoureh Eghbali
Treatment-related biomarkers in pulmonary hypertension patients on oral therapies
Aparna C. Swaminathan, Hongmei Zhu, Victor Tapson, Yuliya Lokhnygina, Abby Poms, Zach Kelleher, Elijah Gaspard, Karla Kennedy, Brian E. Fee, Terry Fortin, S. Nicholas Mason, Kishan Parikh, Tim J. McMahon
Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid interface
Alexandra Noël, Ekhtear Hossain, Zakia Perveen, Hasan Zaman, Arthur L. Penn
Oxygen desaturation during flexible bronchoscopy with propofol sedation is associated with sleep apnea: the PROSA-Study
Andrei M. Darie, Desiree M. Schumann, Marco Laures, Werner Strobel, Kathleen Jahn, Eric Pflimlin, Michael Tamm, Daiana Stolz
The efficacy of mesenchymal stromal cell-derived therapies for acute respiratory distress syndrome—a meta-analysis of preclinical trials
Fengyun Wang, Bin Fang, Xinhua Qiang, Jingsong Shao, Lixin Zhou
Bronchial thermoplasty reduces ventilation heterogeneity measured by multiple breath nitrogen washout
David Langton, Kim Bennetts, Francis Thien, Virginia Plummer, Peter B. Noble
Could KL-6 levels in COVID-19 help to predict lung disease?
AN Frix, L. Schoneveld, A. Ladang, M. Henket, B. Duysinx, F. Vaillant, B. Misset, M. Moutschen, R. Louis, E. Cavalier, J. Guiot
Comparisons of exacerbations and mortality among LAMA/LABA combinations in stable chronic obstructive pulmonary disease: systematic review and Bayesian network meta-analysis
Hyun Woo Lee, Jimyung Park, Eun Jin Jang, Chang-Hoon Lee
COPD burden on sexual well-being
M. Zysman, J. Rubenstein, F. Le Guillou, R. M. H. Colson, C. Pochulu, L. Grassion, R. Escamilla, D. Piperno, J. Pon, S. Khan, C. Raherison-Semjen
Analysis of body mass index, weight loss and progression of idiopathic pulmonary fibrosis
Stéphane Jouneau, Bruno Crestani, Ronan Thibault, Mathieu Lederlin, Laurent Vernhet, Claudia Valenzuela, Marlies Wijsenbeek, Michael Kreuter, Wibke Stansen, Manuel Quaresma, Vincent Cottin
The differences of clinical characteristics and outcomes between imported and local patients of COVID-19 in Hunan: a two-center retrospective study
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