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Erschienen in: European Journal of Orthopaedic Surgery & Traumatology 8/2017

06.06.2017 | Original Article • HIP - OSSIFICATIONS

Results from the surgical resection of severe heterotopic ossification of the hip: a case series of 26 patients

verfasst von: George A. Macheras, Panagiotis Lepetsos, Andreas Leonidou, Panagiotis P. Anastasopoulos, Spyridon P. Galanakos, Eleftherios Tsiridis

Erschienen in: European Journal of Orthopaedic Surgery & Traumatology | Ausgabe 8/2017

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Abstract

Introduction

Surgical resection of heterotopic ossification (HO) around the hip joint is often challenging. The aim of this study is to evaluate the clinical and radiological outcomes following surgical resection of Brooker’s type III and IV HO of the hip.

Methods

We retrospectively reviewed clinical and radiological data, between November 2006 and January 2013, of all patients who underwent surgical resection of severe HO of the hip. Brooker’s grading, range of motion and the Harris Hip Score before and after surgery were recorded in all cases. The combined radiation (700 cGy preoperatively) and indomethacin regimen was used to prevent heterotopic ossification recurrence.

Results

Twenty-six patients (22 males and 4 females) were included in our study. Mean patient age was 47.38 years (range 24–72). The HO was graded as Brooker grade III in 3 patients (11.5%) and Brooker grade IV in 23 patients (88.5%). Mean time interval between HO development and resection was 40.8 months (range 13–156 months). All patients had CT scans prior to surgery. Mean follow-up was 31.4 months (range 24–40 months). There was no severe HO recurrence. Complications included one intraoperative injury of a femoral artery branch, one intraoperative femoral neck fracture treated with intramedullary nailing, one sciatic nerve injury and one superficial infection treated conservatively.

Conclusions

Surgical resection of severe HO of the hip along with preoperative radiation and indomethacin provides excellent results; however, the complication rate is relatively high. Careful evaluation of the preoperative CT scan and wide exposure are required in order to identify all the involved neurovascular structures.
Literatur
4.
5.
Zurück zum Zitat Brooker AF, Bowerman JW, Robinson RA, Riley LH Jr (1973) Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am 55(8):1629–1632CrossRefPubMed Brooker AF, Bowerman JW, Robinson RA, Riley LH Jr (1973) Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am 55(8):1629–1632CrossRefPubMed
6.
Zurück zum Zitat Garland DE (1991) A clinical perspective on common forms of acquired heterotopic ossification. Clin Orthop Relat Res 263:13–29 Garland DE (1991) A clinical perspective on common forms of acquired heterotopic ossification. Clin Orthop Relat Res 263:13–29
8.
Zurück zum Zitat Macfarlane RJ, Ng BH, Gamie Z, El Masry MA, Velonis S, Schizas C, Tsiridis E (2008) Pharmacological treatment of heterotopic ossification following hip and acetabular surgery. Expert Opin Pharmacother 9(5):767–786. doi:10.1517/14656566.9.5.767 CrossRefPubMed Macfarlane RJ, Ng BH, Gamie Z, El Masry MA, Velonis S, Schizas C, Tsiridis E (2008) Pharmacological treatment of heterotopic ossification following hip and acetabular surgery. Expert Opin Pharmacother 9(5):767–786. doi:10.​1517/​14656566.​9.​5.​767 CrossRefPubMed
10.
Zurück zum Zitat Niemi TT, Pitkanen M, Syrjala M, Rosenberg PH (2000) Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty. Acta Anaesthesiol Scand 44(4):457–464CrossRefPubMed Niemi TT, Pitkanen M, Syrjala M, Rosenberg PH (2000) Comparison of hypotensive epidural anaesthesia and spinal anaesthesia on blood loss and coagulation during and after total hip arthroplasty. Acta Anaesthesiol Scand 44(4):457–464CrossRefPubMed
11.
Zurück zum Zitat Moore TJ (1993) Functional outcome following surgical excision of heterotopic ossification in patients with traumatic brain injury. J Orthop Trauma 7(1):11–14CrossRefPubMed Moore TJ (1993) Functional outcome following surgical excision of heterotopic ossification in patients with traumatic brain injury. J Orthop Trauma 7(1):11–14CrossRefPubMed
12.
Zurück zum Zitat Meiners T, Abel R, Bohm V, Gerner HJ (1997) Resection of heterotopic ossification of the hip in spinal cord injured patients. Spinal Cord 35(7):443–445CrossRefPubMed Meiners T, Abel R, Bohm V, Gerner HJ (1997) Resection of heterotopic ossification of the hip in spinal cord injured patients. Spinal Cord 35(7):443–445CrossRefPubMed
13.
Zurück zum Zitat Genet F, Marmorat JL, Lautridou C, Schnitzler A, Mailhan L, Denormandie P (2009) Impact of late surgical intervention on heterotopic ossification of the hip after traumatic neurological injury. J Bone Joint Surg Br 91(11):1493–1498. doi:10.1302/0301-620X.91B11.22305 CrossRefPubMed Genet F, Marmorat JL, Lautridou C, Schnitzler A, Mailhan L, Denormandie P (2009) Impact of late surgical intervention on heterotopic ossification of the hip after traumatic neurological injury. J Bone Joint Surg Br 91(11):1493–1498. doi:10.​1302/​0301-620X.​91B11.​22305 CrossRefPubMed
14.
Zurück zum Zitat Cobb TK, Berry DJ, Wallrichs SL, Ilstrup DM, Morrey BF (1999) Functional outcome of excision of heterotopic ossification after total hip arthroplasty. Clin Orthop Relat Res 361:131–139CrossRef Cobb TK, Berry DJ, Wallrichs SL, Ilstrup DM, Morrey BF (1999) Functional outcome of excision of heterotopic ossification after total hip arthroplasty. Clin Orthop Relat Res 361:131–139CrossRef
16.
Zurück zum Zitat Garland DE, Orwin JF (1989) Resection of heterotopic ossification in patients with spinal cord injuries. Clin Orthop Relat Res 242:169–176 Garland DE, Orwin JF (1989) Resection of heterotopic ossification in patients with spinal cord injuries. Clin Orthop Relat Res 242:169–176
17.
Zurück zum Zitat Ippolito E, Formisano R, Caterini R, Farsetti P, Penta F (1999) Operative treatment of heterotopic hip ossification in patients with coma after brain injury. Clin Orthop Relat Res 365:130–138CrossRef Ippolito E, Formisano R, Caterini R, Farsetti P, Penta F (1999) Operative treatment of heterotopic hip ossification in patients with coma after brain injury. Clin Orthop Relat Res 365:130–138CrossRef
18.
Zurück zum Zitat Wu XB, Yang MH, Zhu SW, Cao QY, Wu HH, Wang MY, Cuellar DO 3rd, Mauffrey C (2014) Surgical resection of severe heterotopic ossification after open reduction and internal fixation of acetabular fractures: a case series of 18 patients. Injury 45(10):1604–1610. doi:10.1016/j.injury.2014.05.018 CrossRefPubMed Wu XB, Yang MH, Zhu SW, Cao QY, Wu HH, Wang MY, Cuellar DO 3rd, Mauffrey C (2014) Surgical resection of severe heterotopic ossification after open reduction and internal fixation of acetabular fractures: a case series of 18 patients. Injury 45(10):1604–1610. doi:10.​1016/​j.​injury.​2014.​05.​018 CrossRefPubMed
19.
Zurück zum Zitat Sodemann B, Persson PE, Nilsson OS (1990) Nonsteroid anti-inflammatory drugs prevent the recurrence of heterotopic ossification after excision. Arch Orthop Trauma Surg 109(2):53–56CrossRefPubMed Sodemann B, Persson PE, Nilsson OS (1990) Nonsteroid anti-inflammatory drugs prevent the recurrence of heterotopic ossification after excision. Arch Orthop Trauma Surg 109(2):53–56CrossRefPubMed
20.
Zurück zum Zitat Warren SB, Brooker AF Jr (1992) Excision of heterotopic bone followed by irradiation after total hip arthroplasty. J Bone Joint Surg Am 74(2):201–210CrossRefPubMed Warren SB, Brooker AF Jr (1992) Excision of heterotopic bone followed by irradiation after total hip arthroplasty. J Bone Joint Surg Am 74(2):201–210CrossRefPubMed
21.
Zurück zum Zitat Wick M, Muller EJ, Hahn MP, Muhr G (1999) Surgical excision of heterotopic bone after hip surgery followed by oral indomethacin application: is there a clinical benefit for the patient? Arch Orthop Trauma Surg 119(3–4):151–155CrossRefPubMed Wick M, Muller EJ, Hahn MP, Muhr G (1999) Surgical excision of heterotopic bone after hip surgery followed by oral indomethacin application: is there a clinical benefit for the patient? Arch Orthop Trauma Surg 119(3–4):151–155CrossRefPubMed
23.
Zurück zum Zitat Koulouvaris P, Tsailas P, Tsiavos K, Soucacos PN (2010) Clinical observations on surgical details of resection of heterotopic ossification at the hip in traumatic brain-injured adult. J Surg Orthop Adv 19(3):177–180PubMed Koulouvaris P, Tsailas P, Tsiavos K, Soucacos PN (2010) Clinical observations on surgical details of resection of heterotopic ossification at the hip in traumatic brain-injured adult. J Surg Orthop Adv 19(3):177–180PubMed
Metadaten
Titel
Results from the surgical resection of severe heterotopic ossification of the hip: a case series of 26 patients
verfasst von
George A. Macheras
Panagiotis Lepetsos
Andreas Leonidou
Panagiotis P. Anastasopoulos
Spyridon P. Galanakos
Eleftherios Tsiridis
Publikationsdatum
06.06.2017
Verlag
Springer Paris
Erschienen in
European Journal of Orthopaedic Surgery & Traumatology / Ausgabe 8/2017
Print ISSN: 1633-8065
Elektronische ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-017-1980-2

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