Rhabdomyoblastic Differentiation in Head and Neck Malignancies Other Than Rhabdomyosarcoma
- 01.12.2015
- Review Paper
Erschienen in:
- Verfasst von
- Justin A. Bishop
- Lester D. R. Thompson
- Antonio Cardesa
- Leon Barnes
- James S. Lewis Jr.
- Asterios Triantafyllou
- Henrik Hellquist
- Goran Stenman
- Jennifer L. Hunt
- Michelle D. Williams
- Pieter J. Slootweg
- Kenneth O. Devaney
- Douglas R. Gnepp
- Bruce M. Wenig
- Alessandra Rinaldo
- Alfio Ferlito
- Erschienen in
- Head and Neck Pathology | Ausgabe 4/2015
Abstract
Rhabdomyosarcoma is a relatively common soft tissue sarcoma that frequently affects children and adolescents and may involve the head and neck. Rhabdomyosarcoma is defined by skeletal muscle differentiation which can be suggested by routine histology and confirmed by immunohistochemistry for the skeletal muscle-specific markers myogenin or myoD1. At the same time, it must be remembered that when it comes to head and neck malignancies, skeletal muscle differentiation is not limited to rhabdomyosarcoma. A lack of awareness of this phenomenon could lead to misdiagnosis and, subsequently, inappropriate therapeutic interventions. This review focuses on malignant neoplasms of the head and neck other than rhabdomyosarcoma that may exhibit rhabdomyoblastic differentiation, with an emphasis on strategies to resolve the diagnostic dilemmas these tumors may present. Axiomatically, no primary central nervous system tumors will be discussed.
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- Titel
- Rhabdomyoblastic Differentiation in Head and Neck Malignancies Other Than Rhabdomyosarcoma
- Verfasst von
-
Justin A. Bishop
Lester D. R. Thompson
Antonio Cardesa
Leon Barnes
James S. Lewis Jr.
Asterios Triantafyllou
Henrik Hellquist
Goran Stenman
Jennifer L. Hunt
Michelle D. Williams
Pieter J. Slootweg
Kenneth O. Devaney
Douglas R. Gnepp
Bruce M. Wenig
Alessandra Rinaldo
Alfio Ferlito
- Publikationsdatum
- 01.12.2015
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 4/2015
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-015-0624-2
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