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Erschienen in:
17.06.2022 | Original Article
Risk Factors for Capsular Contracture in Alloplastic Reconstructive and Augmentation Mammaplasty: Analysis of the National Surgical Quality Improvement Program (NSQIP) Database
Erschienen in: Aesthetic Plastic Surgery | Ausgabe 5/2023
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Background
Capsular contracture is the most common complication of breast augmentation and reconstruction. It occurs in up to 45% of patients and is theorized to occur secondary to an immune reaction. It can lead to pain, dissatisfaction with aesthetic outcomes, and reoperation. The gold standard for management is capsulectomy. Prior similar studies are limited by narrow inclusion criteria, single-surgeon analysis, small sample size, or univariate analysis. The goal of the following study is to prospectively identify possible risk factors for capsular contracture using a national database.
Methods
A retrospective review was conducted utilizing the National Surgical Quality Improvement Program (NSQIP) Database of prospectively collected data of patients undergoing periprosthetic and/or total capsulectomy for capsular contracture from 2013 to 2016. Odds ratios (OR) with 95% confidence intervals (CI) were calculated for variables using a multivariable binary logistic regression model.
Results
A total of 6547 patients underwent reconstructive or augmentation mammaplasty with a prosthetic implant, out of which 2543 (39%) underwent capsulectomy. Capsular contracture was more likely in older (OR: 1.10, 95% CI: 1.09–1.10, p<.001), overweight (OR: 1.12, 95% CI: 1.10–1.13, p<.001), and cancer patients (OR: 7.71, 95% CI: 2.22–28.8, p=0.001). Wound infection was associated with capsulectomy (OR: 6.69, 95% CI: 1.74–25.8, p<.001). Conclusion: These identified risk factors should be comprehensively addressed with patients during the informed consent process before breast augmentation or reconstruction with implants.
Level of Evidence III
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