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International Ophthalmology

Erschienen in:

13.10.2022 | Original Paper

Risk factors for Ex-Press^® surgery failure

verfasst von: Mitsuya Otsuka, Naoki Tojo, Atsushi Hayashi

Erschienen in: International Ophthalmology | Ausgabe 5/2023

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Abstract

Purpose

To investigate the risk factors for Ex-Press^® (EXP) surgery failure.

Patients and methods

This was a retrospective non-randomized study of 98 patients who had undergone EXP and were followed up ≥ 5 years. We investigated the following nine risk factors: age, gender, hypertension, diabetes mellitus (DM), previous glaucoma surgery, type of glaucoma (primary open-angle glaucoma vs. pseudo-exfoliation glaucoma), surgical methods (EXP alone vs. EXP + cataract surgery simultaneously), central corneal thickness (CCT), and preoperative intraocular pressure (IOP). We defined a successful surgery as a postoperative reduction in the IOP ≥ 20% from the preoperative IOP and ≤ 18 mmHg. We determined the risk factors using multivariate cox regression models.

Results

Performing EXP significantly decreased the IOP (preoperative: 25.2 ± 8.7, at 5 years: 11.1 ± 4.1). The success ratio of EXP was 67.4% at 5 years. We found no significant risk factors for EXP surgery failure. The p values of the factors were age (p = 0.936), gender (p = 0.0587), hypertension (p = 0.409), DM (p = 0.967), previous glaucoma surgery (p = 0.940), type of glaucoma (p = 0.435) surgical methods (p = 0.521), CCT (p = 0.091), and preoperative IOP (p = 0.082).

Conclusions

No preoperative factors that could be used to predict the failure of EXP surgery were identified. EXP can be safely performed for primary open-angle glaucoma and pseudo-exfoliation glaucoma.

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Titel: Risk factors for Ex-Press® surgery failure
verfasst von: Mitsuya Otsuka
Naoki Tojo
Atsushi Hayashi
Publikationsdatum: 13.10.2022
Verlag: Springer Netherlands
Erschienen in: International Ophthalmology / Ausgabe 5/2023
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-022-02554-5

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Springer Medizin

Risk factors for Ex-Press^® surgery failure

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Patients and methods

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