Erschienen in:
22.12.2017
Risk factors for pulmonary morbidities after minimally invasive esophagectomy for esophageal cancer
verfasst von:
Tomoyuki Uchihara, Naoya Yoshida, Yoshifumi Baba, Taisuke Yagi, Tasuku Toihata, Eri Oda, Daisuke Kuroda, Tsugio Eto, Mayuko Ohuchi, Kenichi Nakamura, Hiroshi Sawayama, Koichi Kinoshita, Masaaki Iwatsuki, Takatsugu Ishimoto, Yasuo Sakamoto, Hideo Baba
Erschienen in:
Surgical Endoscopy
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Ausgabe 6/2018
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Abstract
Background
Pulmonary morbidities after esophagectomy are still common and are a major cause of surgery-related mortality. The relationship between minimally invasive esophagectomy (MIE) and pulmonary morbidities is not clear. The current study aimed to examine the incidence of pulmonary morbidities after MIE and to clarify the associated risk factors.
Methods
Between May 2011 and December 2016, 184 patients underwent MIE for esophageal cancer. Clinical data were prospectively collected and analyzed. Patient- and surgery-related factors, relating to pulmonary complications, were compared between the complicated and uncomplicated cases.
Results
The incidence of any pulmonary morbidity following MIE was 17.9%. Univariate analysis showed that past heavy smoking [Brinkman index (BI) ≥ 1000], presence of neoadjuvant therapy, advanced clinical stage (stage III, IV), and intraoperative bleeding ≥ 600 g were candidates for being postoperative pulmonary morbidity risk factors. Multivariate analysis suggested that BI ≥ 1000 and advanced clinical stage were independent risk factors for causing pulmonary morbidities.
Conclusions
Past heavy smoking and advanced stage are independent risk factors for pulmonary morbidities after MIE. When performing MIE for such cases, various preoperative precautions and careful postoperative monitoring are necessary.