Skip to main content
Erschienen in: World Journal of Surgery 2/2019

19.10.2018 | Original Scientific Report (including Papers Presented at Surgical Conferences)

Risk Factors for Readmission After Parathyroidectomy for Renal Hyperparathyroidism

verfasst von: Justin D. Lee, Eric J. Kuo, Lin Du, Michael W. Yeh, Masha J. Livhits

Erschienen in: World Journal of Surgery | Ausgabe 2/2019

Einloggen, um Zugang zu erhalten

Abstract

Background

Patients with renal hyperparathyroidism (RHPT) are susceptible to major electrolyte fluctuations following parathyroidectomy, which may predispose them to early readmission. The purpose of this study is to evaluate risk factors for readmission in patients undergoing parathyroidectomy for RHPT.

Methods

Patients with renal failure who underwent parathyroidectomy were abstracted from the California Office of Statewide Health Planning and Development (1999–2012). Multivariable logistic regression was used to identify risk factors for readmission within 30 days of discharge.

Results

The cohort included 4411 patients, of whom 17% were readmitted. Procedures included subtotal parathyroidectomy (74% of cases) and total parathyroidectomy with autotransplantation (26%). Median time to readmission was 9 days (interquartile range 4–16 days). Electrolyte disturbances including hypocalcemia were present in 36% of readmissions and were the most common cause for readmission. Independent risk factors for readmission included Black race [odds ratio (OR) 1.26, 95% confidence interval (CI) 1.00–1.57], Hispanic race (OR 1.38, 95% CI 1.12–1.71), disposition with home health (OR 1.94, 95% CI 1.35–2.77), disposition to a skilled nursing facility (OR 2.30, 95% CI 1.58–3.35), and total parathyroidectomy with autotransplantation (OR 1.27, 95% CI 1.06–1.52). Advancing age (OR 0.98, 95% CI 0.98–0.99) and surgery at a high-volume hospital (OR 0.53, 95% CI 0.36–0.77) were protective against readmission.

Conclusions

Patients undergoing parathyroidectomy for RHPT have a high readmission rate, most frequently for metabolic complications. Increased postoperative vigilance, which may include outpatient laboratory monitoring, may be indicated in patients with risk factors for readmission.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Hedgeman E et al (2015) International Burden of chronic kidney disease and secondary hyperparathyroidism: a systematic review of the literature and available data. Int J Nephrol 2015:1–15CrossRef Hedgeman E et al (2015) International Burden of chronic kidney disease and secondary hyperparathyroidism: a systematic review of the literature and available data. Int J Nephrol 2015:1–15CrossRef
2.
Zurück zum Zitat Cannata-Andía JB, Carrera F (2008) The pathophysiology of secondary hyperparathyroidism and the consequences of uncontrolled mineral metabolism in chronic kidney disease: the role of COSMOS. NDT Plus 1:i2–i6PubMedPubMedCentral Cannata-Andía JB, Carrera F (2008) The pathophysiology of secondary hyperparathyroidism and the consequences of uncontrolled mineral metabolism in chronic kidney disease: the role of COSMOS. NDT Plus 1:i2–i6PubMedPubMedCentral
3.
Zurück zum Zitat Sharma J et al (2012) Improved long-term survival of dialysis patients after near-total parathyroidectomy. J Am Coll Surg 214:400–407 (discussion 407–408) CrossRefPubMedPubMedCentral Sharma J et al (2012) Improved long-term survival of dialysis patients after near-total parathyroidectomy. J Am Coll Surg 214:400–407 (discussion 407–408) CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Ishani A et al (2015) Clinical outcomes after parathyroidectomy in a nationwide cohort of patients on hemodialysis. Clin J Am Soc Nephrol CJASN 10:90–97CrossRefPubMed Ishani A et al (2015) Clinical outcomes after parathyroidectomy in a nationwide cohort of patients on hemodialysis. Clin J Am Soc Nephrol CJASN 10:90–97CrossRefPubMed
5.
Zurück zum Zitat Kuo LE, Wachtel H, Karakousis G, Fraker D, Kelz R (2014) Parathyroidectomy in dialysis patients. J Surg Res 190:554–558CrossRefPubMed Kuo LE, Wachtel H, Karakousis G, Fraker D, Kelz R (2014) Parathyroidectomy in dialysis patients. J Surg Res 190:554–558CrossRefPubMed
7.
Zurück zum Zitat Thomas LE, Pencina MJ (2016) Do not over (P) value your research article. JAMA Cardiol 1:1055CrossRefPubMed Thomas LE, Pencina MJ (2016) Do not over (P) value your research article. JAMA Cardiol 1:1055CrossRefPubMed
8.
Zurück zum Zitat Mullen MG et al (2014) Risk factors for 30-day hospital readmission after thyroidectomy and parathyroidectomy in the United States: an analysis of National Surgical Quality Improvement Program outcomes. Surgery 156:1423–1430 (discussion 1430–1431) CrossRefPubMed Mullen MG et al (2014) Risk factors for 30-day hospital readmission after thyroidectomy and parathyroidectomy in the United States: an analysis of National Surgical Quality Improvement Program outcomes. Surgery 156:1423–1430 (discussion 1430–1431) CrossRefPubMed
9.
Zurück zum Zitat Cunningham J, Locatelli F, Rodriguez M (2011) Secondary hyperparathyroidism: pathogenesis, disease progression, and therapeutic options. Clin J Am Soc Nephrol CJASN 6:913–921CrossRefPubMed Cunningham J, Locatelli F, Rodriguez M (2011) Secondary hyperparathyroidism: pathogenesis, disease progression, and therapeutic options. Clin J Am Soc Nephrol CJASN 6:913–921CrossRefPubMed
11.
Zurück zum Zitat Brasier AR, Nussbaum SR (1988) Hungry bone syndrome: clinical and biochemical predictors of its occurrence after parathyroid surgery. Am J Med 84:654–660CrossRefPubMed Brasier AR, Nussbaum SR (1988) Hungry bone syndrome: clinical and biochemical predictors of its occurrence after parathyroid surgery. Am J Med 84:654–660CrossRefPubMed
12.
Zurück zum Zitat Tsai TC, Joynt KE, Orav EJ, Gawande AA, Jha AK (2013) Variation in surgical-readmission rates and quality of hospital care. N Engl J Med 369:1134–1142CrossRefPubMedPubMedCentral Tsai TC, Joynt KE, Orav EJ, Gawande AA, Jha AK (2013) Variation in surgical-readmission rates and quality of hospital care. N Engl J Med 369:1134–1142CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Mor V, Intrator O, Feng Z, Grabowski DC (2010) The revolving door of rehospitalization from skilled nursing facilities. Health Aff 29:57–64CrossRef Mor V, Intrator O, Feng Z, Grabowski DC (2010) The revolving door of rehospitalization from skilled nursing facilities. Health Aff 29:57–64CrossRef
Metadaten
Titel
Risk Factors for Readmission After Parathyroidectomy for Renal Hyperparathyroidism
verfasst von
Justin D. Lee
Eric J. Kuo
Lin Du
Michael W. Yeh
Masha J. Livhits
Publikationsdatum
19.10.2018
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 2/2019
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-018-4823-3

Weitere Artikel der Ausgabe 2/2019

World Journal of Surgery 2/2019 Zur Ausgabe

Original Scientific Report (including Papers Presented at Surgical Conferences)

Emergency Bleeding Control Interventions After Immediate Total-Body CT Scans in Trauma Patients

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.