Skip to main content
Erschienen in: Annals of Surgical Oncology 7/2012

01.07.2012 | Endocrine Tumors

Robotic Versus Laparoscopic Resection of Large Adrenal Tumors

verfasst von: Orhan Agcaoglu, MD, Shamil Aliyev, MD, Koray Karabulut, MD, Jamie Mitchell, MD, Allan Siperstein, MD, Eren Berber, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 7/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

Although recent studies have shown the feasibility and safety of robotic adrenalectomy, an advantage over the laparoscopic approach has not been demonstrated. Our hypothesis was that the use of the robot would facilitate minimally invasive resection of large adrenal tumors.

Methods

Adrenal tumors ≥5 cm resected robotically were compared with those removed laparoscopically from a prospective institutional review board-approved adrenal database. Clinical and perioperative parameters were analyzed using t and chi-square tests. All data are expressed as mean ± standard error of mean.

Results

There were 24 patients with 25 tumors in the robotic group and 38 patients with 38 tumors in the laparoscopic group. Tumor size was similar in both groups (6.5 ± 0.4 [robotic] vs 6.2 ± 0.3 cm [laparoscopic], P = .661). Operative time was shorter for the robotic versus laparoscopic group (159.4 ± 13.4 vs 187.2 ± 8.3 min, respectively, P = .043), while estimated blood loss was similar (P = .147). The conversion to open rate was less in the robotic (4%) versus the laparoscopic (11%) group; P = .043. Hospital stay was shorter for the robotic group (1.4 ± 0.2 vs 1.9 ± 0.1 days, respectively, P = .009). The 30-day morbidity was 0 in robotic and 2.7% in laparoscopic group. Pathology was similar between groups.

Conclusions

Our study shows that the use of the robot could shorten operative time and decrease the rate of conversion to open for adrenal tumors larger than 5 cm. Based on our favorable experience, robotic adrenalectomy has become our preferred minimally invasive surgical approach for removing large adrenal tumors.
Literatur
1.
Zurück zum Zitat Piazza L, Caragliano P, Scardilli M, Sgroi AV, Marino G, Giannone G. Laparoscopic robot-assisted right adrenalectomy and left ovariectomy (case reports). Chir Ital. 1999:51:465–6.PubMed Piazza L, Caragliano P, Scardilli M, Sgroi AV, Marino G, Giannone G. Laparoscopic robot-assisted right adrenalectomy and left ovariectomy (case reports). Chir Ital. 1999:51:465–6.PubMed
2.
Zurück zum Zitat Hubens G, Ysebaert D, Vaneerdeweg W, Chapelle T, Eyskens E. Laparoscopic adrenalectomy with the aid of the AESOP 2000 robot. Acta Chir Belg. 1999:99:125–7; discussion 127–9.PubMed Hubens G, Ysebaert D, Vaneerdeweg W, Chapelle T, Eyskens E. Laparoscopic adrenalectomy with the aid of the AESOP 2000 robot. Acta Chir Belg. 1999:99:125–7; discussion 127–9.PubMed
3.
Zurück zum Zitat Gill IS, Sung GT, Hsu TH, Meraney AM. Robotic remote laparoscopic nephrectomy and adrenalectomy: the initial experience. J Urol. 2000:164:2082–5.PubMedCrossRef Gill IS, Sung GT, Hsu TH, Meraney AM. Robotic remote laparoscopic nephrectomy and adrenalectomy: the initial experience. J Urol. 2000:164:2082–5.PubMedCrossRef
4.
Zurück zum Zitat Horgan S, Vanuno D. Robots in laparoscopic surgery. J Laparoendosc Adv Surg Tech A. 2001:11:415–9.PubMedCrossRef Horgan S, Vanuno D. Robots in laparoscopic surgery. J Laparoendosc Adv Surg Tech A. 2001:11:415–9.PubMedCrossRef
5.
Zurück zum Zitat Morino M, Beninca G, Giraudo G, Del Genio GM, Rebecchi F, Garrone C. Robot-assisted vs laparoscopic adrenalectomy: a prospective randomized controlled trial. Surg Endosc. 2004:18:1742–6.PubMedCrossRef Morino M, Beninca G, Giraudo G, Del Genio GM, Rebecchi F, Garrone C. Robot-assisted vs laparoscopic adrenalectomy: a prospective randomized controlled trial. Surg Endosc. 2004:18:1742–6.PubMedCrossRef
6.
Zurück zum Zitat Corcione F, Esposito C, Cuccurullo D, Settembre A, Miranda N, Amato F, et al. Advantages and limits of robot-assisted laparoscopic surgery: preliminary experience. Surg Endosc. 2005:19:117–9.PubMedCrossRef Corcione F, Esposito C, Cuccurullo D, Settembre A, Miranda N, Amato F, et al. Advantages and limits of robot-assisted laparoscopic surgery: preliminary experience. Surg Endosc. 2005:19:117–9.PubMedCrossRef
7.
Zurück zum Zitat Winter JM, Talamini MA, Stanfield CL, Chang DC, Hundt JD, Dackiw AP, et al. Thirty robotic adrenalectomies: a single institution’s experience. Surg Endosc. 2006:20:119–24.PubMedCrossRef Winter JM, Talamini MA, Stanfield CL, Chang DC, Hundt JD, Dackiw AP, et al. Thirty robotic adrenalectomies: a single institution’s experience. Surg Endosc. 2006:20:119–24.PubMedCrossRef
8.
Zurück zum Zitat Brunaud L, Ayav A, Zarnegar R, Rouers A, Klein M, Boissel P, et al. Prospective evaluation of 100 robotic-assisted unilateral adrenalectomies. Surgery. 2008:144:995–1001; discussion 1001.PubMedCrossRef Brunaud L, Ayav A, Zarnegar R, Rouers A, Klein M, Boissel P, et al. Prospective evaluation of 100 robotic-assisted unilateral adrenalectomies. Surgery. 2008:144:995–1001; discussion 1001.PubMedCrossRef
9.
Zurück zum Zitat Giulianotti PC, Buchs NC, Addeo P, Bianco FM, Ayloo SM, Caravaglios G, et al. Robot-assisted adrenalectomy: a technical option for the surgeon? Int J Med Robot. 2011:7:27–32.PubMedCrossRef Giulianotti PC, Buchs NC, Addeo P, Bianco FM, Ayloo SM, Caravaglios G, et al. Robot-assisted adrenalectomy: a technical option for the surgeon? Int J Med Robot. 2011:7:27–32.PubMedCrossRef
10.
Zurück zum Zitat Choi KH, Ham WS, Rha KH, Lee JW, Jeon HG, Arkoncel FR, et al. Laparoendoscopic single-site surgeries: a single-center experience of 171 consecutive cases. Korean J Urol. 2011:52:31–8.PubMedCrossRef Choi KH, Ham WS, Rha KH, Lee JW, Jeon HG, Arkoncel FR, et al. Laparoendoscopic single-site surgeries: a single-center experience of 171 consecutive cases. Korean J Urol. 2011:52:31–8.PubMedCrossRef
12.
Zurück zum Zitat Kumar R, Hemal AK. Emerging role of robotics in urology. J Minim Access Surg. 2005:1:202–10.PubMed Kumar R, Hemal AK. Emerging role of robotics in urology. J Minim Access Surg. 2005:1:202–10.PubMed
13.
Zurück zum Zitat Brunaud L, Bresler L, Ayav A, Zarnegar R, Raphoz AL, Levan T, et al. Robotic-assisted adrenalectomy: what advantages compared to lateral transperitoneal laparoscopic adrenalectomy? Am J Surg. 2008:195:433–8.PubMedCrossRef Brunaud L, Bresler L, Ayav A, Zarnegar R, Raphoz AL, Levan T, et al. Robotic-assisted adrenalectomy: what advantages compared to lateral transperitoneal laparoscopic adrenalectomy? Am J Surg. 2008:195:433–8.PubMedCrossRef
14.
Zurück zum Zitat Berber E, Mitchell J, Milas M, Siperstein A. Robotic posterior retroperitoneal adrenalectomy: operative technique. Arch Surg. 2010:145:781–4.PubMedCrossRef Berber E, Mitchell J, Milas M, Siperstein A. Robotic posterior retroperitoneal adrenalectomy: operative technique. Arch Surg. 2010:145:781–4.PubMedCrossRef
15.
Zurück zum Zitat Berber E, Tellioglu G, Harvey A, Mitchell J, Milas M, Siperstein A. Comparison of laparoscopic transabdominal lateral versus posterior retroperitoneal adrenalectomy. Surgery. 2009:146:621–5; discussion 625–6.PubMedCrossRef Berber E, Tellioglu G, Harvey A, Mitchell J, Milas M, Siperstein A. Comparison of laparoscopic transabdominal lateral versus posterior retroperitoneal adrenalectomy. Surgery. 2009:146:621–5; discussion 625–6.PubMedCrossRef
16.
Zurück zum Zitat Siperstein AE, Berber E, Engle KL, Duh QY, Clark OH. Laparoscopic posterior adrenalectomy: technical considerations. Arch Surg. 2000:135:967–71.PubMedCrossRef Siperstein AE, Berber E, Engle KL, Duh QY, Clark OH. Laparoscopic posterior adrenalectomy: technical considerations. Arch Surg. 2000:135:967–71.PubMedCrossRef
17.
Zurück zum Zitat Hemal AK, Singh A, Gupta NP. Whether adrenal mass more than 5 cm can pose problem in laparoscopic adrenalectomy? An evaluation of 22 patients. World J Urol. 2008:26:505–8.PubMedCrossRef Hemal AK, Singh A, Gupta NP. Whether adrenal mass more than 5 cm can pose problem in laparoscopic adrenalectomy? An evaluation of 22 patients. World J Urol. 2008:26:505–8.PubMedCrossRef
18.
Zurück zum Zitat Henry JF, Sebag F, Iacobone M, Mirallie E. Results of laparoscopic adrenalectomy for large and potentially malignant tumors. World J Surg. 2002:26:1043–7.PubMedCrossRef Henry JF, Sebag F, Iacobone M, Mirallie E. Results of laparoscopic adrenalectomy for large and potentially malignant tumors. World J Surg. 2002:26:1043–7.PubMedCrossRef
19.
Zurück zum Zitat Parnaby CN, Chong PS, Chisholm L, Farrow J, Connell JM, O’Dwyer PJ. The role of laparoscopic adrenalectomy for adrenal tumours of 6 cm or greater. Surg Endosc. 2008:22:617–21.PubMedCrossRef Parnaby CN, Chong PS, Chisholm L, Farrow J, Connell JM, O’Dwyer PJ. The role of laparoscopic adrenalectomy for adrenal tumours of 6 cm or greater. Surg Endosc. 2008:22:617–21.PubMedCrossRef
20.
Zurück zum Zitat Ramacciato G, Mercantini P, La Torre M, Di Benedetto F, Ercolani G, Ravaioli M, et al. Is laparoscopic adrenalectomy safe and effective for adrenal masses larger than 7 cm? Surg Endosc. 2008:22:516–21.PubMedCrossRef Ramacciato G, Mercantini P, La Torre M, Di Benedetto F, Ercolani G, Ravaioli M, et al. Is laparoscopic adrenalectomy safe and effective for adrenal masses larger than 7 cm? Surg Endosc. 2008:22:516–21.PubMedCrossRef
21.
Zurück zum Zitat Rosoff JS, Raman JD, Del Pizzo JJ. Laparoscopic adrenalectomy for large adrenal masses. Curr Urol Rep. 2008:9:73–9.PubMedCrossRef Rosoff JS, Raman JD, Del Pizzo JJ. Laparoscopic adrenalectomy for large adrenal masses. Curr Urol Rep. 2008:9:73–9.PubMedCrossRef
22.
Zurück zum Zitat Boris RS, Gupta G, Linehan WM, Pinto PA, Bratslavsky G. Robot-assisted laparoscopic partial adrenalectomy: initial experience. Urology. 2011:77:775–80.PubMedCrossRef Boris RS, Gupta G, Linehan WM, Pinto PA, Bratslavsky G. Robot-assisted laparoscopic partial adrenalectomy: initial experience. Urology. 2011:77:775–80.PubMedCrossRef
23.
Zurück zum Zitat Bruhn AM, Hyams ES, Stifelman MD. Laparoscopic and robotic assisted adrenal surgery. Minerva Urol Nefrol. 2010:62:305–18.PubMed Bruhn AM, Hyams ES, Stifelman MD. Laparoscopic and robotic assisted adrenal surgery. Minerva Urol Nefrol. 2010:62:305–18.PubMed
24.
25.
Zurück zum Zitat Krane LS, Shrivastava A, Eun D, Narra V, Bhandari M, Menon M. A four-step technique of robotic right adrenalectomy: initial experience. BJU Int. 2008:101:1289–92.PubMedCrossRef Krane LS, Shrivastava A, Eun D, Narra V, Bhandari M, Menon M. A four-step technique of robotic right adrenalectomy: initial experience. BJU Int. 2008:101:1289–92.PubMedCrossRef
26.
Zurück zum Zitat Brunaud L, Bresler L, Zarnegar R, Ayav A, Cormier L, Tretou S, et al. Does robotic adrenalectomy improve patient quality of life when compared to laparoscopic adrenalectomy? World J Surg. 2004:28:1180–5.PubMedCrossRef Brunaud L, Bresler L, Zarnegar R, Ayav A, Cormier L, Tretou S, et al. Does robotic adrenalectomy improve patient quality of life when compared to laparoscopic adrenalectomy? World J Surg. 2004:28:1180–5.PubMedCrossRef
27.
Zurück zum Zitat Miller BS, Ammori JB, Gauger PG, Broome JT, Hammer GD, Doherty GM. Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma. World J Surg. 2010:34:1380–5.PubMedCrossRef Miller BS, Ammori JB, Gauger PG, Broome JT, Hammer GD, Doherty GM. Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma. World J Surg. 2010:34:1380–5.PubMedCrossRef
28.
Zurück zum Zitat Porpiglia F, Fiori C, Daffara F, Zaggia B, Bollito E, Volante M, et al. Retrospective evaluation of the outcome of open versus laparoscopic adrenalectomy for stage I and II adrenocortical cancer. Eur Urol. 2010:57:873–8.PubMedCrossRef Porpiglia F, Fiori C, Daffara F, Zaggia B, Bollito E, Volante M, et al. Retrospective evaluation of the outcome of open versus laparoscopic adrenalectomy for stage I and II adrenocortical cancer. Eur Urol. 2010:57:873–8.PubMedCrossRef
29.
Zurück zum Zitat Brix D, Allolio B, Fenske W, Agha A, Dralle H, Jurowich C, et al. Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients. Eur Urol. 2010:58:609–15.PubMedCrossRef Brix D, Allolio B, Fenske W, Agha A, Dralle H, Jurowich C, et al. Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients. Eur Urol. 2010:58:609–15.PubMedCrossRef
30.
Zurück zum Zitat Karabulut K, Agcaoglu O, Aliyev S, Siperstein A, Berber E. Comparison of intraoperative time use and perioperative outcomes for robotic versus laparoscopic adrenalectomy. Surgery. 2011 Dec 3 (Epub ahead of print). Karabulut K, Agcaoglu O, Aliyev S, Siperstein A, Berber E. Comparison of intraoperative time use and perioperative outcomes for robotic versus laparoscopic adrenalectomy. Surgery. 2011 Dec 3 (Epub ahead of print).
Metadaten
Titel
Robotic Versus Laparoscopic Resection of Large Adrenal Tumors
verfasst von
Orhan Agcaoglu, MD
Shamil Aliyev, MD
Koray Karabulut, MD
Jamie Mitchell, MD
Allan Siperstein, MD
Eren Berber, MD
Publikationsdatum
01.07.2012
Verlag
Springer-Verlag
Erschienen in
Annals of Surgical Oncology / Ausgabe 7/2012
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-012-2296-4

Weitere Artikel der Ausgabe 7/2012

Annals of Surgical Oncology 7/2012 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.