New devices for transcatheter aortic valve implantation, mitral repair, and closure of prosthetic paravalvular leaks have expanded the options for catheter-based approaches to patients with regurgitant as well as stenotic valvular disease. Echocardiography (2-dimensional and 3-dimensional) plays an important role in identifying patients suitable for these interventions, helps provide peri-procedural monitoring, and is essential for post-procedure follow-up. The optimal use of echocardiography requires an understanding of the structure and method of implantation of available devices, the anatomic and functional patient selection criteria, and imaging characteristics of implanted devices, particularly those that differ from devices used in traditional surgical interventions. This document describes the role of echocardiography in the most commonly performed transcatheter interventions for valvular heart disease: transcatheter aortic valve implantation, MitraClip mitral valve repair, and transcatheter perivalvular leak closure.