Skip to main content
Erschienen in: Lasers in Medical Science 8/2020

31.01.2020 | Original Article

Role of low-level laser therapy in post-herpetic neuralgia: a pilot study

verfasst von: Rushqia Mukhtar, M. Umar Fazal, M. Saleem, Salman Saleem

Erschienen in: Lasers in Medical Science | Ausgabe 8/2020

Einloggen, um Zugang zu erhalten

Abstract

The aim of the present study was to investigate the influence of low-level laser radiation at a wavelength of 650 nm for treating post-herpetic neuralgia, an extremely painful condition which frequently occurs severely in old age and may persist for years with no predictable course. In total, fifteen patients were included in the present study, out of which 8 were females and 7 were males aged between 42 and 82 years. All patients were treated through 16 sessions for 8 weeks, and pain scoring was done on a visual analogue scale and statistical analysis was made for comparison before and after treatments. The final pain score was 0 in 11 patients although their initial pain score was severe in 8 and moderate in 3 patients. In three patients, pain reduced to mild intensity (2–3), and in one, the final pain score was 4 on the visual analogue scale. Patients treated during the present study have not complained for recurrence of pain or any other abnormality even after many months since completion of the therapy. Overall, low-level laser therapy (LLLT) proved itself an excellent therapeutic modality for the relief of pain in post-herpetic neuralgia patients, which may replace pain management medicines in future.
Literatur
1.
Zurück zum Zitat Merrick RV, Kahn F, Saraga F (2013) Treatment of postherpetic neuralgia with low level laser therapy. Pract Pain Manag 13:1CrossRef Merrick RV, Kahn F, Saraga F (2013) Treatment of postherpetic neuralgia with low level laser therapy. Pract Pain Manag 13:1CrossRef
2.
Zurück zum Zitat Vernon LF, Hasbun RJ (2008) Low-level laser therapy for trigeminal neuralgia. Pract Pain Manag 8:1CrossRef Vernon LF, Hasbun RJ (2008) Low-level laser therapy for trigeminal neuralgia. Pract Pain Manag 8:1CrossRef
3.
Zurück zum Zitat Mendlik MT, Uritsky TJ (2015) Treatment of neuropathic pain. Curr Treat Options Neurol 17:50CrossRef Mendlik MT, Uritsky TJ (2015) Treatment of neuropathic pain. Curr Treat Options Neurol 17:50CrossRef
4.
Zurück zum Zitat de Andrade AL, Bossini PS, Parizotto NA (2016) Use of low level laser therapy to control neuropathic pain: a systematic review. J Photochem Photobiol B Biol 164:36–42CrossRef de Andrade AL, Bossini PS, Parizotto NA (2016) Use of low level laser therapy to control neuropathic pain: a systematic review. J Photochem Photobiol B Biol 164:36–42CrossRef
5.
Zurück zum Zitat Falaki F, Nejat AH, Dalirsani Z (2014) The effect of low-level laser therapy on trigeminal neuralgia: a review of literature. J Dent Res Dent Clin Dent Prospects 8:1–5PubMedPubMedCentral Falaki F, Nejat AH, Dalirsani Z (2014) The effect of low-level laser therapy on trigeminal neuralgia: a review of literature. J Dent Res Dent Clin Dent Prospects 8:1–5PubMedPubMedCentral
6.
Zurück zum Zitat Waked I, Attalla A, Eid M (2015) Low level laser therapy for the treatment of trigeminal neuralgia after oral surgeries: two different applications. Int J Heal Rehabil Sci 4:10–18CrossRef Waked I, Attalla A, Eid M (2015) Low level laser therapy for the treatment of trigeminal neuralgia after oral surgeries: two different applications. Int J Heal Rehabil Sci 4:10–18CrossRef
7.
Zurück zum Zitat Moore KC, Hira N, Parswanath PS, Jayakumar CS, Ohshiro T (2004) A double blind crossover trial of low level laser therapy in the treatment of posttherpetic neuralgia. Laser Ther 14:61–64CrossRef Moore KC, Hira N, Parswanath PS, Jayakumar CS, Ohshiro T (2004) A double blind crossover trial of low level laser therapy in the treatment of posttherpetic neuralgia. Laser Ther 14:61–64CrossRef
8.
Zurück zum Zitat Knapp DJ (2013) Postherpetic neuralgia: case study of class 4 laser therapy intervention. Clin J Pain 29:e6–e9CrossRef Knapp DJ (2013) Postherpetic neuralgia: case study of class 4 laser therapy intervention. Clin J Pain 29:e6–e9CrossRef
9.
Zurück zum Zitat Chen YT, Wang HH, Wang TJ, Li YC, Chen TJ (2016) Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN). J Am Acad Dermatol 75:572–577CrossRef Chen YT, Wang HH, Wang TJ, Li YC, Chen TJ (2016) Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN). J Am Acad Dermatol 75:572–577CrossRef
10.
Zurück zum Zitat Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR (2012) The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 40:516–533CrossRef Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR (2012) The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 40:516–533CrossRef
11.
Zurück zum Zitat William JK (2006) Practical applications of low level laser therapy. Pract Pain Manag 6:1CrossRef William JK (2006) Practical applications of low level laser therapy. Pract Pain Manag 6:1CrossRef
12.
Zurück zum Zitat Karu TI (2003) Low-power laser therapy. In: Biomedical photonics handbook. CRC Press, pp 1–26 Karu TI (2003) Low-power laser therapy. In: Biomedical photonics handbook. CRC Press, pp 1–26
13.
Zurück zum Zitat Huang Y (2009) Low-level laser therapy: an emerging clinical paradigm. SPIE Newsroom Huang Y (2009) Low-level laser therapy: an emerging clinical paradigm. SPIE Newsroom
14.
Zurück zum Zitat Kingsley JD, Demchak T, Mathis R (2014) Low-level laser therapy as a treatment for chronic pain. Front Physiol 5:306CrossRef Kingsley JD, Demchak T, Mathis R (2014) Low-level laser therapy as a treatment for chronic pain. Front Physiol 5:306CrossRef
15.
Zurück zum Zitat da Silva JP, da Silva MA, Almeida AP, Lombardi JI, Matos AP (2010) Laser therapy in the tissue repair process: a literature review. Photomed Laser Surg 28:17–21CrossRef da Silva JP, da Silva MA, Almeida AP, Lombardi JI, Matos AP (2010) Laser therapy in the tissue repair process: a literature review. Photomed Laser Surg 28:17–21CrossRef
16.
Zurück zum Zitat Hamblin MR, Huang Y (2013) Handbook of photomedicine. CRC Press, Taylor & Francis Group Hamblin MR, Huang Y (2013) Handbook of photomedicine. CRC Press, Taylor & Francis Group
17.
Zurück zum Zitat da Rosa AS, dos Santos AF, da Silva MM, Facco GG, Perreira DM, Alves AC, Leal Junior EC, de Carvalho PT (2012) Effects of low-level laser therapy at wavelengths of 660 and 808 nm in experimental model of osteoarthritis. Photochem Photobiol 88:161–166CrossRef da Rosa AS, dos Santos AF, da Silva MM, Facco GG, Perreira DM, Alves AC, Leal Junior EC, de Carvalho PT (2012) Effects of low-level laser therapy at wavelengths of 660 and 808 nm in experimental model of osteoarthritis. Photochem Photobiol 88:161–166CrossRef
18.
Zurück zum Zitat Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA (2006) Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158–168CrossRef Bjordal JM, Johnson MI, Iversen V, Aimbire F, Lopes-Martins RA (2006) Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Laser Surg 24:158–168CrossRef
19.
Zurück zum Zitat Anand V, Gulati M, Govila V, Anand B (2013) Low level laser therapy in the treatment of aphthous ulcer. Indian J Dent Res 24:267–270CrossRef Anand V, Gulati M, Govila V, Anand B (2013) Low level laser therapy in the treatment of aphthous ulcer. Indian J Dent Res 24:267–270CrossRef
20.
Zurück zum Zitat Aggarwal H, Singh MP, Nahar P, Mathur H, Gv S (2014) Efficacy of low-level laser therapy in treatment of recurrent aphthous ulcers – a sham controlled, split mouth follow up study. J Clin Diagn Res 8:218–221PubMedPubMedCentral Aggarwal H, Singh MP, Nahar P, Mathur H, Gv S (2014) Efficacy of low-level laser therapy in treatment of recurrent aphthous ulcers – a sham controlled, split mouth follow up study. J Clin Diagn Res 8:218–221PubMedPubMedCentral
21.
Zurück zum Zitat Wu S, Chen Y, Zhang J, Chen W, Shao S, Shen H, Zhu L, Ye P, Svensson P, Wang K (2018) Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment. Int J Oral Sci 10:22CrossRef Wu S, Chen Y, Zhang J, Chen W, Shao S, Shen H, Zhu L, Ye P, Svensson P, Wang K (2018) Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment. Int J Oral Sci 10:22CrossRef
22.
Zurück zum Zitat Papageorgiou P, Katsambas A, Chu A (2000) Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris. Br J Dermatol 142:973–978CrossRef Papageorgiou P, Katsambas A, Chu A (2000) Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris. Br J Dermatol 142:973–978CrossRef
23.
Zurück zum Zitat Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M (2005) Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg 31:334–340CrossRef Posten W, Wrone DA, Dover JS, Arndt KA, Silapunt S, Alam M (2005) Low-level laser therapy for wound healing: mechanism and efficacy. Dermatol Surg 31:334–340CrossRef
24.
Zurück zum Zitat Elman M, Lebzelter J (2004) Light therapy in the treatment of acne vulgaris. Dermatol Surg 30:139–146PubMed Elman M, Lebzelter J (2004) Light therapy in the treatment of acne vulgaris. Dermatol Surg 30:139–146PubMed
25.
Zurück zum Zitat Hamilton FL, Car J, Lyons C, Car M, Layton A, Majeed A (2009) Laser and other light therapies for the treatment of acne vulgaris: systematic review. Br J Dermatol 160:1273–1285CrossRef Hamilton FL, Car J, Lyons C, Car M, Layton A, Majeed A (2009) Laser and other light therapies for the treatment of acne vulgaris: systematic review. Br J Dermatol 160:1273–1285CrossRef
26.
Zurück zum Zitat Munavalli GS, Weiss RA (2008) Evidence for laser- and light-based treatment of acne vulgaris. Semin Cutan Med Surg 27:207–211CrossRef Munavalli GS, Weiss RA (2008) Evidence for laser- and light-based treatment of acne vulgaris. Semin Cutan Med Surg 27:207–211CrossRef
27.
Zurück zum Zitat Erdle BJ, Brouxhon S, Kaplan M, Vanbuskirk J, Pentland AP (2008) Effects of continuous-wave (670-nm) red light on wound healing. Dermatol Surg 34:320–325PubMed Erdle BJ, Brouxhon S, Kaplan M, Vanbuskirk J, Pentland AP (2008) Effects of continuous-wave (670-nm) red light on wound healing. Dermatol Surg 34:320–325PubMed
28.
Zurück zum Zitat Karu TI (2010) Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation. IUBMB Life 62:607–610CrossRef Karu TI (2010) Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation. IUBMB Life 62:607–610CrossRef
29.
Zurück zum Zitat Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR (2013) Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg 32:41–52PubMedPubMedCentral Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR (2013) Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg 32:41–52PubMedPubMedCentral
30.
Zurück zum Zitat Weijie G, Hongmei L, Wei L (2017) Intense pulsed light therapy. In: Photomedicine - advances in clinical practice. InTechOpen Limited UK Weijie G, Hongmei L, Wei L (2017) Intense pulsed light therapy. In: Photomedicine - advances in clinical practice. InTechOpen Limited UK
31.
Zurück zum Zitat Aswendt M, Adamczak J, Tennstaedt A (2014) A review of novel optical imaging strategies of the stroke pathology and stem cell therapy in stroke. Front Cell Neurosci 8:226CrossRef Aswendt M, Adamczak J, Tennstaedt A (2014) A review of novel optical imaging strategies of the stroke pathology and stem cell therapy in stroke. Front Cell Neurosci 8:226CrossRef
32.
Zurück zum Zitat Gibney MA, Arce CH, Byron KJ, Hirsch LJ (2010) Skin and subcutaneous adipose layer thickness in adults with diabetes at sites used for insulin injections: implications for needle length recommendations. Curr Med Res Opin 26:1519–1530CrossRef Gibney MA, Arce CH, Byron KJ, Hirsch LJ (2010) Skin and subcutaneous adipose layer thickness in adults with diabetes at sites used for insulin injections: implications for needle length recommendations. Curr Med Res Opin 26:1519–1530CrossRef
33.
Zurück zum Zitat Haefeli M, Elfering A (2006) Pain assessment. Eur Spine J 15(Suppl 1):S17–S24CrossRef Haefeli M, Elfering A (2006) Pain assessment. Eur Spine J 15(Suppl 1):S17–S24CrossRef
Metadaten
Titel
Role of low-level laser therapy in post-herpetic neuralgia: a pilot study
verfasst von
Rushqia Mukhtar
M. Umar Fazal
M. Saleem
Salman Saleem
Publikationsdatum
31.01.2020
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 8/2020
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-020-02969-5

Weitere Artikel der Ausgabe 8/2020

Lasers in Medical Science 8/2020 Zur Ausgabe