Electronic supplementary material
What is Known:
• RSV infection is responsible for a significant burden of disease in young children worldwide.
• Severe RSV infection in early life is associated with asthmatic symptoms later in life.
What is New:
• This is the largest published birth cohort reporting about the role of atopic predisposition in the link between severe RSV infection and current wheeze at school age.
• We show that RSV hospitalization in infancy is an independent risk factor for current wheeze in late preterm children without atopic predisposition at age 6. This was not seen in children with atopic predisposition.