Erschienen in:
04.02.2018 | Case Report
Rupture of Hepatocellular Carcinoma: a Tale of 20 Cases from a Tertiary Care Center in Northern India
verfasst von:
Srimanta Kumar Sahu, S. Taneja, N. Kalra, R. K. Dhiman, Y. K. Chawla, A. Duseja, V. Singh
Erschienen in:
Journal of Gastrointestinal Cancer
|
Ausgabe 3/2019
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Excerpt
Approximately 700,000 people die of hepatocellular carcinoma (HCC) each year worldwide, making it the third leading cause of cancer-related deaths [
1]. HCC develops in the background of cirrhotic liver in 85–95% of cases [
2]. Spontaneous rupture is a potentially life-threatening complication and is the third most common cause of death due to HCC after tumor progression and liver failure [
3]. In Asia, approximately 10% of patients with HCC die of rupture each year [
4]. There is a distinct geographical variation in the reported incidence of ruptured HCC. In the West, HCC rupture is relatively uncommon, with an incidence of less than 3% [
5]. However in Asia, the incidence is relatively higher, ranging between 3 and 26% [
6]. The literature on rupture HCC is scarce from India and there is no data on the exact incidence of HCC rupture from India [
7,
8]. …