The online version of this article (doi:10.1186/1471-2296-15-104) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests. Stefan Vormfelde is employee of Novartis since February 2014, thus after manuscript submission and without influence on any part of the paper.
Funding for the study was obtained by JFC and SVV. All authors were involved in the design and conduct of the study. The analysis of data was the main responsibility of TF and SS. All authors contributed to manuscript drafting and revision and approved the final manuscript.
Effective and safe management of oral anticoagulant treatment (OAT) requires a high level of patient knowledge and adherence. The aim of this study was to assess patient knowledge about OAT and factors associated with patient knowledge.
This is a baseline survey of a cluster-randomized controlled trial in 22 general practices with an educational intervention for patients or their caregivers. We assessed knowledge about general information on OAT and key facts regarding nutrition, drug-interactions and other safety precautions of 345 patients at baseline.
Participants rated their knowledge about OAT as excellent to good (56%), moderate (36%) or poor (8%). However, there was a discrepancy between self-rated knowledge and evaluated actual knowledge and we observed serious knowledge gaps. Half of the participants (49%) were unaware of dietary recommendations. The majority (80%) did not know which non-prescription analgesic is the safest and 73% indicated they would not inform pharmacists about OAT. Many participants (35-75%) would not recognize important emergency situations. After adjustment in a multivariate analysis, older age and less than 10 years education remained significantly associated with lower overall score, but not with self-rated knowledge.
Patients have relevant knowledge gaps, potentially affecting safe and effective OAT. There is a need to assess patient knowledge and for structured education programs.
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- Safety relevant knowledge of orally anticoagulated patients without self-monitoring: a baseline survey in primary care
Thanh Duc Hua
Manar Abu Abed
Stefan Viktor Vormfelde
- BioMed Central
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