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Erschienen in: The Indian Journal of Pediatrics 12-13/2016

14.06.2016 | Scientific Letter

Salivary Cortisol Based Early ACTH Test for Identifying Adrenal Insufficiency in Low Birth Weight Infants

verfasst von: Ori Hochwald, Liisa Holsti, Horacio Osiovich

Erschienen in: Indian Journal of Pediatrics | Ausgabe 12-13/2016

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Excerpt

To the Editor: In premature newborns, a variety of etiologies result in early hypotension [1]. Transient adrenal insufficiency (TAI) is one etiology which is difficult to diagnose in this group [2]. ACTH test is superior to random cortisol levels to diagnose TAI [3]. In a former study, an increase in serum cortisol below 12 % from baseline during ACTH study had 93 % specificity for detecting hypotension that was treated with inotropes, and thus suspected to be a clinical sign of adrenal insufficiency [4]. …
Literatur
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Zurück zum Zitat Watterberg KL. Adrenocortical function and dysfunction in the fetus and neonate. Semin Neonatol. 2004;9:13–21.CrossRefPubMed Watterberg KL. Adrenocortical function and dysfunction in the fetus and neonate. Semin Neonatol. 2004;9:13–21.CrossRefPubMed
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Zurück zum Zitat Heckmann M, Wudy SA, Haack D, Pohlandt F. Reference range for serum cortisol in well preterm infants. Arch Dis Child Fetal Neonatal Ed. 1999;81:F171–4.CrossRefPubMedPubMedCentral Heckmann M, Wudy SA, Haack D, Pohlandt F. Reference range for serum cortisol in well preterm infants. Arch Dis Child Fetal Neonatal Ed. 1999;81:F171–4.CrossRefPubMedPubMedCentral
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Metadaten
Titel
Salivary Cortisol Based Early ACTH Test for Identifying Adrenal Insufficiency in Low Birth Weight Infants
verfasst von
Ori Hochwald
Liisa Holsti
Horacio Osiovich
Publikationsdatum
14.06.2016
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 12-13/2016
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-016-2177-0

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