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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Salmonella enterica ssp. arizonae infection in a 43-year-old Italian man with hypoglobulinemia: a case report and review of the literature

Journal of Medical Case Reports > Ausgabe 1/2011
Stefano Di Bella, Alessandro Capone, Eugenio Bordi, Emma Johnson, Maria Musso, Simone Topino, Pasquale Noto, Nicola Petrosillo
Wichtige Hinweise

Competing interests

NP has received industry honoraria for lecturing from Wyeth, GSK, Pfizer, MSD, Novartis, Sanofi Aventis, Janssen Cilag, Carefusion, Astellas, Gilead. All other authors report no conflicts.

Authors' contributions

SD and MM monitored our patient during hospitalization and analyzed data from the literature. EB isolated and identified the bacterium. AC, PN and ST performed the follow-up of our patient after discharge. EJ was the major contributor in writing the manuscript. NP reviewed the manuscript. All authors have read and approved the final manuscript.



Salmonella enterica ssp. arizonae is an uncommon human pathogen with serious infections reported in immunocompromised hosts. In Europe, only a few cases have been described. Patients with this infection usually have a history of contact with reptiles or travel abroad. We present a case report of infection in a patient with hypoglobulinemia and a literature review.

Case presentation

We describe the case of a 43-year-old Caucasian Italian man with hypoglobulinemia who presented to our hospital with sepsis and diarrhea. A stool culture yielded S. enterica ssp. arizonae. Our patient was treated with oral ciprofloxacin and made a full recovery. We also present a review of the cases of S. enterica ssp. arizonae infections previously reported in Europe.


The majority of infections from S. enterica ssp. arizonae occur in patients who are immunocompromised. Data from the literature suggests that it may be difficult to eradicate the bacteria and thus, prolonged antibiotic courses are often used. It would be advisable for clinicians to investigate for pre-existing immune dysfunction if S. enterica ssp. arizonae is isolated. In Italy, although there have only been a few cases, the likely route of transmission remains unclear and requires further surveillance.

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