Erschienen in:
01.09.2003 | Editorial
Salt saves the hot brain?
verfasst von:
Nino Stocchetti
Erschienen in:
Intensive Care Medicine
|
Ausgabe 9/2003
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Excerpt
In their paper "Effects of hypertonic (3%) saline in rats with circulatory shock and cerebral ischemia after heatstroke", Lin and co-authors present an experimental study on the cerebral effects of heat shock and the potential utility of hypertonic saline [
1]. Exposure to high ambient temperature in their model causes systemic hypotension and intracranial hypertension, with a consequent drop of cerebral perfusion pressure. Correspondingly, cerebral blood flow decreases, leading to reduced tissue oxygenation and neurochemical changes indicative of severe cellular damage. …