Even if severe asthma (SA) accounts for 5–10% of all cases of the disease, it is currently a crucial unmet need, owing its difficult clinical management and its high social costs. For this reason several networks, focused on SA have been organized in some countries, in order to select these patients, to recognize their clinical features, to evaluate their adherence, to classify their biological/clinical phenotypes, to identify their eligibility to the new biologic therapies and to quantify the costs of the disease. Aim of the present paper is to describe the ongoing Italian Severe Asthma Network (SANI). Up today 49 centres have been selected, widespread on the national territory. Sharing the same diagnostic protocol, data regarding patients with SA will be collected and processed in a web platform. After their recruitment, SA patients will be followed in the long term in order to investigate the natural history of the disease. Besides clinical data, the cost/benefit evaluation of the new biologics will be verified as well as the search of peculiar biomarker(s) of the disease.
Chung KF, Wenzel SE, Brozek JL, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Resp J. 2014;43:343–73. CrossRef
Global initiative for asthma, update 2016. http://www.ginasthma.org. Accessed 28 Dec 2016.
Vennera MD, De Llano LP, Bardagi S, et al. Omalizuman therapy in severe asthma:experience from the Spanish Registry-Some new approaches. J Asthma. 2012;49:416–22. CrossRef
Maio S, Baldacci S, Bresciani M, et al, on behalf of the AGAVE group. RItA: The Italian severe/uncontrolled asthma registry (under revision).
Novelli F, Latorre M, Vergura L, et al, on behalf of the Xolair Italian Study Group. Asthma control in severe asthmatics under treatment with omalizumab: a cross-sectional observational study in Italy. Pulm Pharmacol Ther. 2015;31:123–9.
- SANI-Severe Asthma Network in Italy: a way forward to monitor severe asthma
P. L. Paggiaro
G. W. Canonica
on Behalf of SANI
- BioMed Central
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