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Erschienen in: Der Schmerz 3/2021

18.12.2020 | Pädiatrie | Pain Clinical Updates

Pädiatrische Schmerztherapie und -prävention bei hospitalisierten Kindern

verfasst von: Stefan J. Friedrichsdorf, Liesbet Goubert

Erschienen in: Der Schmerz | Ausgabe 3/2021

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Zusammenfassung

Einleitung

Schmerzprävention und -therapie sind bei pädiatrischen Patienten im Vergleich zu Erwachsenen häufig nicht nur mangelhaft, sie werden auch umso seltener umgesetzt, je jünger die Kinder sind. Kinder und Jugendliche von 0 bis 17 Jahren sind eine vulnerable Gruppe.

Zielsetzung

Der vorliegende Beitrag befasst sich mit der Prävention und Therapie von akutem und chronischem Schmerz bei Kindern, einschließlich des Schmerzes bei Nadelstichen. In diesem Rahmen werden auch empfohlene analgetische Anfangsdosen angegeben.

Methoden

Dieses klinische Update basiert auf einem Datenblatt zur Schmerztherapie bei Kindern („Factsheet Pain in Children: Management“) der IASP-Kampagne Global Year Against Pain in the Vulnerable von 2019 und fasst die beste Evidenz sowie das beste praktische Vorgehen zusammen.

Ergebnisse

Im Rahmen der multimodalen Schmerztherapie können Arzneimittel (z. B. Basisanalgetika, Opioide und Koanalgetika), Regionalanästhesie, Rehabilitation, psychologische Ansätze, Spiritualität und integrative Verfahren eingesetzt werden, die synergistisch eine wirksamere akute pädiatrische Schmerzkontrolle mit weniger Nebenwirkungen ermöglichen als die einzelnen Analgetika oder Therapieverfahren. Bei chronischem Schmerz hat sich ein interdisziplinärer rehabilitativer Ansatz mit Physiotherapie, Psychotherapie, integrativen Mind-body-Verfahren und Normalisierung der Lebensführung als am wirksamsten erwiesen. In Bezug auf elektive Verfahren, die mit einem Nadelstich verbunden sind, wie Blutentnahmen, venöser Zugang, Injektionen oder Impfungen, führt die Studienlage zu der Forderung, dass jedem Kind in jeder solchen Situation ein Bündel von vier Maßnahmen geboten werden soll, um den Schmerz vollständig oder teilweise zu lindern: (1) topische Anästhesie, z. B. mit Lidocaincreme 4 %, (2) behaglich-beruhigende Positionierung, z. B. Haut-zu-Haut-Kontakt bei Säuglingen, keine Fixierung von Kindern, (3) Saccharose oder Stillen von Säuglingen und (4) altersgerechte Ablenkung. Eine mögliche Ausweichlösung (Plan B) ist die Lachgasanalgesie und -sedierung.

Schlussfolgerung

Die ausbleibende Implementierung einer evidenzbasierten Schmerzprävention und -therapie für Kinder in medizinischen Einrichtungen gilt heute als unzulässig und zeugt von einer schlechten Versorgungsqualität.
Literatur
1.
Zurück zum Zitat American Society of Anesthesiologists Task Force on S, Analgesia by N‑A (2002) Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96:1004–1017 American Society of Anesthesiologists Task Force on S, Analgesia by N‑A (2002) Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96:1004–1017
2.
Zurück zum Zitat Anand KJ, Barton BA, McIntosh N, Lagercrantz H, Pelausa E, Young TE, Vasa R (1999) Analgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal outcome and prolonged analgesia in neonates. Arch Pediatr Adolesc Med 153:331–338PubMed Anand KJ, Barton BA, McIntosh N, Lagercrantz H, Pelausa E, Young TE, Vasa R (1999) Analgesia and sedation in preterm neonates who require ventilatory support: results from the NOPAIN trial. Neonatal outcome and prolonged analgesia in neonates. Arch Pediatr Adolesc Med 153:331–338PubMed
3.
Zurück zum Zitat Baeumler PI, Fleckenstein J, Benedikt F, Bader J, Irnich D (2015) Acupuncture-induced changes of pressure pain threshold are mediated by segmental inhibition—a randomized controlled trial. Pain 156:2245–2255PubMed Baeumler PI, Fleckenstein J, Benedikt F, Bader J, Irnich D (2015) Acupuncture-induced changes of pressure pain threshold are mediated by segmental inhibition—a randomized controlled trial. Pain 156:2245–2255PubMed
4.
Zurück zum Zitat Benoit B, Campbell-Yeo M, Johnston C, Latimer M, Caddell K, Orr T (2016) Staff nurse utilization of kangaroo care as an intervention for procedural pain in preterm infants. Adv Neonatal Care 16:229–238PubMed Benoit B, Campbell-Yeo M, Johnston C, Latimer M, Caddell K, Orr T (2016) Staff nurse utilization of kangaroo care as an intervention for procedural pain in preterm infants. Adv Neonatal Care 16:229–238PubMed
5.
Zurück zum Zitat Beyer JE, DeGood DE, Ashley LC, Russell GA (1983) Patterns of postoperative analgesic use with adults and children following cardiac surgery. Pain 17:71–81PubMed Beyer JE, DeGood DE, Ashley LC, Russell GA (1983) Patterns of postoperative analgesic use with adults and children following cardiac surgery. Pain 17:71–81PubMed
6.
Zurück zum Zitat Birnie KA, Chambers CT, Fernandez CV, Forgeron PA, Latimer MA, McGrath PJ, Cummings EA, Finley GA (2014) Hospitalized children continue to report undertreated and preventable pain. Pain Res Manag 19:198–204PubMedPubMedCentral Birnie KA, Chambers CT, Fernandez CV, Forgeron PA, Latimer MA, McGrath PJ, Cummings EA, Finley GA (2014) Hospitalized children continue to report undertreated and preventable pain. Pain Res Manag 19:198–204PubMedPubMedCentral
8.
Zurück zum Zitat Brattberg G (2004) Do pain problems in young school children persist into early adulthood? A 13-year follow-up. Eur J Pain 8:187–199PubMed Brattberg G (2004) Do pain problems in young school children persist into early adulthood? A 13-year follow-up. Eur J Pain 8:187–199PubMed
9.
Zurück zum Zitat Broome ME, Richtsmeier A, Maikler V, Alexander M (1996) Pediatric pain practices: a national survey of health professionals. J Pain Symptom Manage 11:312–320PubMed Broome ME, Richtsmeier A, Maikler V, Alexander M (1996) Pediatric pain practices: a national survey of health professionals. J Pain Symptom Manage 11:312–320PubMed
10.
Zurück zum Zitat Burns J, Jackson K, Sheehy KA, Finkel JC, Quezado ZM (2017) The use of dexmedetomidine in pediatric palliative care: a preliminary study. J Palliat Med 20:779–783PubMed Burns J, Jackson K, Sheehy KA, Finkel JC, Quezado ZM (2017) The use of dexmedetomidine in pediatric palliative care: a preliminary study. J Palliat Med 20:779–783PubMed
11.
Zurück zum Zitat Burns DA (2018) Using regional anesthesia to manage pediatric acute pain. 11th Pediatric Pain Master’s Class (Conference), Minneapolis Burns DA (2018) Using regional anesthesia to manage pediatric acute pain. 11th Pediatric Pain Master’s Class (Conference), Minneapolis
12.
Zurück zum Zitat Bussing A, Ostermann T, Ludtke R, Michalsen A (2012) Effects of yoga interventions on pain and pain-associated disability: a meta-analysis. J Pain 13:1–9PubMed Bussing A, Ostermann T, Ludtke R, Michalsen A (2012) Effects of yoga interventions on pain and pain-associated disability: a meta-analysis. J Pain 13:1–9PubMed
13.
Zurück zum Zitat Bussolin L, Busoni P, Giorgi L, Crescioli M, Messeri A (2003) Tumescent local anesthesia for the surgical treatment of burns and postburn sequelae in pediatric patients. Anesthesiology 99:1371–1375PubMed Bussolin L, Busoni P, Giorgi L, Crescioli M, Messeri A (2003) Tumescent local anesthesia for the surgical treatment of burns and postburn sequelae in pediatric patients. Anesthesiology 99:1371–1375PubMed
14.
Zurück zum Zitat Campbell-Yeo M, Johnston C, Benoit B, Latimer M, Vincer M, Walker CD, Streiner D, Inglis D, Caddell K (2013) Trial of repeated analgesia with kangaroo mother care (TRAKC trial). BMC Pediatr 13:182PubMedPubMedCentral Campbell-Yeo M, Johnston C, Benoit B, Latimer M, Vincer M, Walker CD, Streiner D, Inglis D, Caddell K (2013) Trial of repeated analgesia with kangaroo mother care (TRAKC trial). BMC Pediatr 13:182PubMedPubMedCentral
15.
Zurück zum Zitat Campbell-Yeo ML, Johnston CC, Joseph KS, Feeley N, Chambers CT, Barrington KJ, Walker CD (2014) Co-bedding between preterm twins attenuates stress response after heel lance: results of a randomized trial. Clin J Pain 30:598–604PubMed Campbell-Yeo ML, Johnston CC, Joseph KS, Feeley N, Chambers CT, Barrington KJ, Walker CD (2014) Co-bedding between preterm twins attenuates stress response after heel lance: results of a randomized trial. Clin J Pain 30:598–604PubMed
16.
Zurück zum Zitat Campbell-Yeo ML, Disher TC, Benoit BL, Johnston CC (2015) Understanding kangaroo care and its benefits to preterm infants. Pediatr Health Med Ther 6:15–32 Campbell-Yeo ML, Disher TC, Benoit BL, Johnston CC (2015) Understanding kangaroo care and its benefits to preterm infants. Pediatr Health Med Ther 6:15–32
17.
Zurück zum Zitat Campbell-Yeo M, Johnston CC, Benoit B, Disher T, Caddell K, Vincer M, Walker CD, Latimer M, Streiner DL, Inglis D (2019) Sustained efficacy of kangaroo care for repeated painful procedures over neonatal intensive care unit hospitalization: a single-blind randomized controlled trial. Pain 160:2580–2588PubMed Campbell-Yeo M, Johnston CC, Benoit B, Disher T, Caddell K, Vincer M, Walker CD, Latimer M, Streiner DL, Inglis D (2019) Sustained efficacy of kangaroo care for repeated painful procedures over neonatal intensive care unit hospitalization: a single-blind randomized controlled trial. Pain 160:2580–2588PubMed
19.
Zurück zum Zitat Casadio P, Fernandes C, Murray RM, Di Forti M (2011) Cannabis use in young people: the risk for schizophrenia. Neurosci Biobehav Rev 35:1779–1787PubMed Casadio P, Fernandes C, Murray RM, Di Forti M (2011) Cannabis use in young people: the risk for schizophrenia. Neurosci Biobehav Rev 35:1779–1787PubMed
20.
Zurück zum Zitat Centre for Pediatric Pain Research (2016) Centre for pediatric pain research. It doesn’t have to hurt. Halifax, nova scotia, Canada: centre for pediatric pain research. http://itdoesnthavetohurt.ca. Zugegriffen: 3. Dez. 2019 Centre for Pediatric Pain Research (2016) Centre for pediatric pain research. It doesn’t have to hurt. Halifax, nova scotia, Canada: centre for pediatric pain research. http://​itdoesnthavetohu​rt.​ca. Zugegriffen: 3. Dez. 2019
21.
Zurück zum Zitat CHEO’s Be Sweet to Babies Research Team, University of Ottawa’s School of Nursing (2014) CHEO’s Be Sweet to Babies Research Team and the University of Ottawa’s School of Nursing. Be sweet to babies. Ottowa, Ontario, Canada: Children’s Hospital of Eastern Ontario. http://www.cheo.on.ca/en/BeSweet2Babies. Zugegriffen: 3. Dez. 2019 CHEO’s Be Sweet to Babies Research Team, University of Ottawa’s School of Nursing (2014) CHEO’s Be Sweet to Babies Research Team and the University of Ottawa’s School of Nursing. Be sweet to babies. Ottowa, Ontario, Canada: Children’s Hospital of Eastern Ontario. http://​www.​cheo.​on.​ca/​en/​BeSweet2Babies. Zugegriffen: 3. Dez. 2019
22.
Zurück zum Zitat Chidambaran V, Sadhasivam S, Mahmoud M (2017) Codeine and opioid metabolism: implications and alternatives for pediatric pain management. Curr Opin Anaesthesiol 30:349–356PubMedPubMedCentral Chidambaran V, Sadhasivam S, Mahmoud M (2017) Codeine and opioid metabolism: implications and alternatives for pediatric pain management. Curr Opin Anaesthesiol 30:349–356PubMedPubMedCentral
23.
Zurück zum Zitat Chrysostomou C, Schulman SR, Herrera Castellanos M, Cofer BE, Mitra S, da Rocha MG, Wisemandle WA, Gramlich L (2014) A phase II/III, multicenter, safety, efficacy, and pharmacokinetic study of dexmedetomidine in preterm and term neonates. J Pediatr 164:276–282.e1‑3PubMed Chrysostomou C, Schulman SR, Herrera Castellanos M, Cofer BE, Mitra S, da Rocha MG, Wisemandle WA, Gramlich L (2014) A phase II/III, multicenter, safety, efficacy, and pharmacokinetic study of dexmedetomidine in preterm and term neonates. J Pediatr 164:276–282.e1‑3PubMed
24.
Zurück zum Zitat Ciszkowski C, Madadi P, Phillips MS, Lauwers AE, Koren G (2009) Codeine, ultrarapid-metabolism genotype, and postoperative death. N Engl J Med 361:827–828PubMed Ciszkowski C, Madadi P, Phillips MS, Lauwers AE, Koren G (2009) Codeine, ultrarapid-metabolism genotype, and postoperative death. N Engl J Med 361:827–828PubMed
25.
Zurück zum Zitat Cousins LA, Kalapurakkel S, Cohen LL, Simons LE (2015) Topical review: resilience resources and mechanisms in pediatric chronic pain. J Pediatr Psychol 40:840–845PubMedPubMedCentral Cousins LA, Kalapurakkel S, Cohen LL, Simons LE (2015) Topical review: resilience resources and mechanisms in pediatric chronic pain. J Pediatr Psychol 40:840–845PubMedPubMedCentral
26.
Zurück zum Zitat Cuignet O, Pirson J, Boughrouph J, Duville D (2004) The efficacy of continuous fascia iliaca compartment block for pain management in burn patients undergoing skin grafting procedures. Anesth Analg 98:1077–1081 (table of contents)PubMed Cuignet O, Pirson J, Boughrouph J, Duville D (2004) The efficacy of continuous fascia iliaca compartment block for pain management in burn patients undergoing skin grafting procedures. Anesth Analg 98:1077–1081 (table of contents)PubMed
27.
Zurück zum Zitat Cuignet O, Mbuyamba J, Pirson J (2005) The long-term analgesic efficacy of a single-shot fascia iliaca compartment block in burn patients undergoing skin-grafting procedures. J Burn Care Rehabil 26:409–415PubMed Cuignet O, Mbuyamba J, Pirson J (2005) The long-term analgesic efficacy of a single-shot fascia iliaca compartment block in burn patients undergoing skin-grafting procedures. J Burn Care Rehabil 26:409–415PubMed
28.
Zurück zum Zitat Daling JR, Doody DR, Sun X, Trabert BL, Weiss NS, Chen C, Biggs ML, Starr JR, Dey SK, Schwartz SM (2009) Association of marijuana use and the incidence of testicular germ cell tumors. Cancer 115:1215–1223PubMed Daling JR, Doody DR, Sun X, Trabert BL, Weiss NS, Chen C, Biggs ML, Starr JR, Dey SK, Schwartz SM (2009) Association of marijuana use and the incidence of testicular germ cell tumors. Cancer 115:1215–1223PubMed
29.
Zurück zum Zitat Deshpande A, Mailis-Gagnon A, Zoheiry N, Lakha SF (2015) Efficacy and adverse effects of medical marijuana for chronic noncancer pain: systematic review of randomized controlled trials. Can Fam Physician 61:e372–e381PubMedPubMedCentral Deshpande A, Mailis-Gagnon A, Zoheiry N, Lakha SF (2015) Efficacy and adverse effects of medical marijuana for chronic noncancer pain: systematic review of randomized controlled trials. Can Fam Physician 61:e372–e381PubMedPubMedCentral
30.
Zurück zum Zitat Eccleston C, Malleson PN, Clinch J, Connell H, Sourbut C (2003) Chronic pain in adolescents: evaluation of a programme of interdisciplinary cognitive behaviour therapy. Arch Dis Child 88:881–885PubMedPubMedCentral Eccleston C, Malleson PN, Clinch J, Connell H, Sourbut C (2003) Chronic pain in adolescents: evaluation of a programme of interdisciplinary cognitive behaviour therapy. Arch Dis Child 88:881–885PubMedPubMedCentral
32.
Zurück zum Zitat Edwards KM, Hackell JM, Committee on Infectious Diseases TCOP, Ambulatory M (2016) Countering vaccine hesitancy. Pediatrics 138:e20162146PubMed Edwards KM, Hackell JM, Committee on Infectious Diseases TCOP, Ambulatory M (2016) Countering vaccine hesitancy. Pediatrics 138:e20162146PubMed
33.
Zurück zum Zitat Edwards L, DeMeo S, Hornik CD, Cotten CM, Smith PB, Pizoli C, Hauer JM, Bidegain M (2016) Gabapentin use in the neonatal intensive care unit. J Pediatr 169:310–312PubMed Edwards L, DeMeo S, Hornik CD, Cotten CM, Smith PB, Pizoli C, Hauer JM, Bidegain M (2016) Gabapentin use in the neonatal intensive care unit. J Pediatr 169:310–312PubMed
34.
Zurück zum Zitat Evans S, Tsao JC, Zeltzer LK (2008) Complementary and alternative medicine for acute procedural pain in children. Altern Ther Health Med 14:52–56PubMed Evans S, Tsao JC, Zeltzer LK (2008) Complementary and alternative medicine for acute procedural pain in children. Altern Ther Health Med 14:52–56PubMed
35.
Zurück zum Zitat Evans S, Tsao JC, Zeltzer LK (2008) Paediatric pain management: using complementary and alternative medicine. Rev Pain 2:14–20PubMedPubMedCentral Evans S, Tsao JC, Zeltzer LK (2008) Paediatric pain management: using complementary and alternative medicine. Rev Pain 2:14–20PubMedPubMedCentral
36.
Zurück zum Zitat Evans S, Moieni M, Taub R, Subramanian SK, Tsao JC, Sternlieb B, Zeltzer LK (2010) Iyengar yoga for young adults with rheumatoid arthritis: results from a mixed-methods pilot study. J Pain Symptom Manage 39:904–913PubMed Evans S, Moieni M, Taub R, Subramanian SK, Tsao JC, Sternlieb B, Zeltzer LK (2010) Iyengar yoga for young adults with rheumatoid arthritis: results from a mixed-methods pilot study. J Pain Symptom Manage 39:904–913PubMed
38.
Zurück zum Zitat Ferrini R, Paice JA (2004) How to initiate and monitor infusional lidocaine for severe and/or neuropathic pain. J Support Oncol 2:90–94PubMed Ferrini R, Paice JA (2004) How to initiate and monitor infusional lidocaine for severe and/or neuropathic pain. J Support Oncol 2:90–94PubMed
39.
Zurück zum Zitat Finkel J, Pestieau S, Quezado Z (2007) Ketamine as an adjuvant for treatment of cancer pain in children and adolescents. J Pain 8:515–521PubMed Finkel J, Pestieau S, Quezado Z (2007) Ketamine as an adjuvant for treatment of cancer pain in children and adolescents. J Pain 8:515–521PubMed
40.
Zurück zum Zitat Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpaa M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M (2015) Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 14:162–173PubMedPubMedCentral Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpaa M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M (2015) Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 14:162–173PubMedPubMedCentral
43.
Zurück zum Zitat Friedrichsdorf SJ, Kohen DP (2018) Integration of hypnosis into pediatric palliative care. Ann Palliat Med 7:136–150PubMed Friedrichsdorf SJ, Kohen DP (2018) Integration of hypnosis into pediatric palliative care. Ann Palliat Med 7:136–150PubMed
44.
Zurück zum Zitat Friedrichsdorf SJ, Nugent AP (2013) Management of neuropathic pain in children with cancer. Curr Opin Support Palliat Care 7:131–138PubMed Friedrichsdorf SJ, Nugent AP (2013) Management of neuropathic pain in children with cancer. Curr Opin Support Palliat Care 7:131–138PubMed
45.
Zurück zum Zitat Friedrichsdorf S, Kuttner L, Westendorp K, McCarty R (2010) Integrative pediatric palliative care. In. In: Culbert TP, Olness K (Hrsg) Integrative pediatrics. Oxford University Press, Oxford, S 569–593 Friedrichsdorf S, Kuttner L, Westendorp K, McCarty R (2010) Integrative pediatric palliative care. In. In: Culbert TP, Olness K (Hrsg) Integrative pediatrics. Oxford University Press, Oxford, S 569–593
46.
Zurück zum Zitat Friedrichsdorf SJ, Nugent AP, Strobl AQ (2013) Codeine-associated pediatric deaths despite using recommended dosing guidelines: three case reports. J Opioid Manag 9:151–155PubMed Friedrichsdorf SJ, Nugent AP, Strobl AQ (2013) Codeine-associated pediatric deaths despite using recommended dosing guidelines: three case reports. J Opioid Manag 9:151–155PubMed
47.
Zurück zum Zitat Friedrichsdorf SJ, Postier A, Eull D, Weidner C, Foster L, Gilbert M, Campbell F (2015) Pain outcomes in a US children’s hospital: a prospective cross-sectional survey. Hosp Pediatr 5:18–26PubMed Friedrichsdorf SJ, Postier A, Eull D, Weidner C, Foster L, Gilbert M, Campbell F (2015) Pain outcomes in a US children’s hospital: a prospective cross-sectional survey. Hosp Pediatr 5:18–26PubMed
48.
Zurück zum Zitat Friedrichsdorf SJ, Postier AC, Foster LP, Lander TA, Tibesar RJ, Lu Y, Sidman JD (2015) Tramadol versus codeine/acetaminophen after pediatric tonsillectomy: a prospective, double-blinded, randomized controlled trial. J Opioid Manag 11:283–294PubMed Friedrichsdorf SJ, Postier AC, Foster LP, Lander TA, Tibesar RJ, Lu Y, Sidman JD (2015) Tramadol versus codeine/acetaminophen after pediatric tonsillectomy: a prospective, double-blinded, randomized controlled trial. J Opioid Manag 11:283–294PubMed
49.
Zurück zum Zitat Friedrichsdorf SJ, Giordano J, Desai Dakoji K, Warmuth A, Daughtry C, Schulz CA (2016) Chronic pain in children and adolescents: diagnosis and treatment of primary pain disorders in head, abdomen, muscles and joints. Children 3:42PubMedCentral Friedrichsdorf SJ, Giordano J, Desai Dakoji K, Warmuth A, Daughtry C, Schulz CA (2016) Chronic pain in children and adolescents: diagnosis and treatment of primary pain disorders in head, abdomen, muscles and joints. Children 3:42PubMedCentral
50.
Zurück zum Zitat Friedrichsdorf SJ, Sidman J, Krane EJ (2016) Prevention and treatment of pain in children: toward a paradigm shift. Otolaryngol Head Neck Surg 154:804–805PubMed Friedrichsdorf SJ, Sidman J, Krane EJ (2016) Prevention and treatment of pain in children: toward a paradigm shift. Otolaryngol Head Neck Surg 154:804–805PubMed
51.
Zurück zum Zitat Friedrichsdorf SJ, Eull D, Weidner C, Postier A (2018) A hospital-wide initiative to eliminate or reduce needle pain in children using lean methodology. Pain Rep 3(suppl 1):e671PubMedPubMedCentral Friedrichsdorf SJ, Eull D, Weidner C, Postier A (2018) A hospital-wide initiative to eliminate or reduce needle pain in children using lean methodology. Pain Rep 3(suppl 1):e671PubMedPubMedCentral
52.
Zurück zum Zitat Friedrichsdorf SJ (2017) Nitrous gas analgesia and sedation for lumbar punctures in children: has the time for practice change come? Pediatr Blood Cancer 64:11 Friedrichsdorf SJ (2017) Nitrous gas analgesia and sedation for lumbar punctures in children: has the time for practice change come? Pediatr Blood Cancer 64:11
53.
Zurück zum Zitat Friedrichsdorf SJ (2019) From tramadol to methadone: opioids in the treatment of pain and dyspnea in pediatric palliative care. Clin J Pain 35:501–508PubMed Friedrichsdorf SJ (2019) From tramadol to methadone: opioids in the treatment of pain and dyspnea in pediatric palliative care. Clin J Pain 35:501–508PubMed
54.
Zurück zum Zitat Friedrichsdorf SJ (2016) Prevention and treatment of pain in hospitalized infants, children, and Teenagers: from myths and morphine to multimodal analgesia. In: International Association for the Study of Pain (Hrsg) Pain 2016: refresher courses 16th World Congress on Pain. IASP Press, Washington, DC, S 309–319 Friedrichsdorf SJ (2016) Prevention and treatment of pain in hospitalized infants, children, and Teenagers: from myths and morphine to multimodal analgesia. In: International Association for the Study of Pain (Hrsg) Pain 2016: refresher courses 16th World Congress on Pain. IASP Press, Washington, DC, S 309–319
55.
Zurück zum Zitat Gao H, Gao H, Xu G, Li M, Du S, Li F, Zhang H, Wang D (2016) Efficacy and safety of repeated oral sucrose for repeated procedural pain in neonates: a systematic review. Int J Nurs Stud 62:118–125PubMed Gao H, Gao H, Xu G, Li M, Du S, Li F, Zhang H, Wang D (2016) Efficacy and safety of repeated oral sucrose for repeated procedural pain in neonates: a systematic review. Int J Nurs Stud 62:118–125PubMed
56.
Zurück zum Zitat Gauntlett-Gilbert J, Connell H, Clinch J, McCracken LM (2013) Acceptance and values-based treatment of adolescents with chronic pain: outcomes and their relationship to acceptance. J Pediatr Psychol 38:72–81PubMed Gauntlett-Gilbert J, Connell H, Clinch J, McCracken LM (2013) Acceptance and values-based treatment of adolescents with chronic pain: outcomes and their relationship to acceptance. J Pediatr Psychol 38:72–81PubMed
57.
Zurück zum Zitat Goodman JE, McGrath PJ (1991) The epidemiology of pain in children and adolescents: a review. Pain 46:247–264PubMed Goodman JE, McGrath PJ (1991) The epidemiology of pain in children and adolescents: a review. Pain 46:247–264PubMed
59.
Zurück zum Zitat Goubert L, Simons LE (2013) Cognitive styles and processes in paediatric pain. In: McGrath P, Stevens B, Walker S, Zempsky WT (Hrsg) Oxford textbook of paediatric pain. Oxford University Press, Oxford, S 95–101 Goubert L, Simons LE (2013) Cognitive styles and processes in paediatric pain. In: McGrath P, Stevens B, Walker S, Zempsky WT (Hrsg) Oxford textbook of paediatric pain. Oxford University Press, Oxford, S 95–101
60.
Zurück zum Zitat Goubert L, Trompetter H (2017) Towards a science and practice of resilience in the face of pain. Eur J Pain 21:1301–1315PubMed Goubert L, Trompetter H (2017) Towards a science and practice of resilience in the face of pain. Eur J Pain 21:1301–1315PubMed
61.
Zurück zum Zitat Goubert L, Pillai-Riddell R, Simons L, Borsook D (2019) Theoretical basis of pain. In: McGrath P, Stevens B, Walker S, Zemsky W (Hrsg) Oxford textbook of paediatric pain, 2. Aufl. Oxford University Press, Oxford, S 95–101 Goubert L, Pillai-Riddell R, Simons L, Borsook D (2019) Theoretical basis of pain. In: McGrath P, Stevens B, Walker S, Zemsky W (Hrsg) Oxford textbook of paediatric pain, 2. Aufl. Oxford University Press, Oxford, S 95–101
62.
63.
Zurück zum Zitat Gray L, Garza E, Zageris D, Heilman KJ, Porges SW (2015) Sucrose and warmth for analgesia in healthy newborns: an RCT. Pediatrics 135:e607–e614PubMedPubMedCentral Gray L, Garza E, Zageris D, Heilman KJ, Porges SW (2015) Sucrose and warmth for analgesia in healthy newborns: an RCT. Pediatrics 135:e607–e614PubMedPubMedCentral
64.
Zurück zum Zitat Grossoehme DH, Szczesniak R, McPhail GL, Seid M (2013) Is adolescents’ religious coping with cystic fibrosis associated with the rate of decline in pulmonary function?—A preliminary study. J Health Care Chaplain 19:33–42PubMedPubMedCentral Grossoehme DH, Szczesniak R, McPhail GL, Seid M (2013) Is adolescents’ religious coping with cystic fibrosis associated with the rate of decline in pulmonary function?—A preliminary study. J Health Care Chaplain 19:33–42PubMedPubMedCentral
65.
Zurück zum Zitat Grunau RE, Whitfield MF, Petrie-Thomas J, Synnes AR, Cepeda IL, Keidar A, Rogers M, Mackay M, Hubber-Richard P, Johannesen D (2009) Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants. Pain 143:138–146PubMedPubMedCentral Grunau RE, Whitfield MF, Petrie-Thomas J, Synnes AR, Cepeda IL, Keidar A, Rogers M, Mackay M, Hubber-Richard P, Johannesen D (2009) Neonatal pain, parenting stress and interaction, in relation to cognitive and motor development at 8 and 18 months in preterm infants. Pain 143:138–146PubMedPubMedCentral
66.
Zurück zum Zitat Hartley C, Poorun R, Goksan S, Worley A, Boyd S, Rogers R, Ali T, Slater R (2014) Noxious stimulation in children receiving general anaesthesia evokes an increase in delta frequency brain activity. Pain 155:2368–2376PubMedPubMedCentral Hartley C, Poorun R, Goksan S, Worley A, Boyd S, Rogers R, Ali T, Slater R (2014) Noxious stimulation in children receiving general anaesthesia evokes an increase in delta frequency brain activity. Pain 155:2368–2376PubMedPubMedCentral
67.
Zurück zum Zitat Hauer JM, Solodiuk JC (2015) Gabapentin for management of recurrent pain in 22 nonverbal children with severe neurological impairment: a retrospective analysis. J Palliat Med 18:453–456PubMed Hauer JM, Solodiuk JC (2015) Gabapentin for management of recurrent pain in 22 nonverbal children with severe neurological impairment: a retrospective analysis. J Palliat Med 18:453–456PubMed
68.
Zurück zum Zitat Hayes SC, Strosahl KD, Wilson KG (2012) Acceptance and commitment therapy: the process and practice of mindful change, 2. Aufl. Guilford, New York Hayes SC, Strosahl KD, Wilson KG (2012) Acceptance and commitment therapy: the process and practice of mindful change, 2. Aufl. Guilford, New York
69.
Zurück zum Zitat Heathcote LC, Rabner J, Lebel A, Hernandez JM, Simons LE (2018) Rapid screening of risk in pediatric headache: application of the pediatric pain screening tool. J Pediatr Psychol 43:243–251PubMed Heathcote LC, Rabner J, Lebel A, Hernandez JM, Simons LE (2018) Rapid screening of risk in pediatric headache: application of the pediatric pain screening tool. J Pediatr Psychol 43:243–251PubMed
70.
Zurück zum Zitat Hechler T, Dobe M, Zernikow B (2010) Commentary: a worldwide call for multimodal inpatient treatment for children and adolescents suffering from chronic pain and pain-related disability. J Pediatr Psychol 35:138–140PubMed Hechler T, Dobe M, Zernikow B (2010) Commentary: a worldwide call for multimodal inpatient treatment for children and adolescents suffering from chronic pain and pain-related disability. J Pediatr Psychol 35:138–140PubMed
72.
Zurück zum Zitat Hernandez JL, Savetamal A, Crombie RE, Cholewczynski W, Atweh N, Possenti P, Schulz JT III (2013) Use of continuous local anesthetic infusion in the management of postoperative split-thickness skin graft donor site pain. J Burn Care Res 34:e257–e262PubMed Hernandez JL, Savetamal A, Crombie RE, Cholewczynski W, Atweh N, Possenti P, Schulz JT III (2013) Use of continuous local anesthetic infusion in the management of postoperative split-thickness skin graft donor site pain. J Burn Care Res 34:e257–e262PubMed
73.
Zurück zum Zitat Hestbaek L, Leboeuf-Yde C, Kyvik KO, Manniche C (2006) The course of low back pain from adolescence to adulthood: eight-year follow-up of 9600 twins. Spine 31:468–472PubMed Hestbaek L, Leboeuf-Yde C, Kyvik KO, Manniche C (2006) The course of low back pain from adolescence to adulthood: eight-year follow-up of 9600 twins. Spine 31:468–472PubMed
74.
Zurück zum Zitat Hexem KR, Mollen CJ, Carroll K, Lanctot DA, Feudtner C (2011) How parents of children receiving pediatric palliative care use religion, spirituality, or life philosophy in tough times. J Palliat Med 14:39–44PubMedPubMedCentral Hexem KR, Mollen CJ, Carroll K, Lanctot DA, Feudtner C (2011) How parents of children receiving pediatric palliative care use religion, spirituality, or life philosophy in tough times. J Palliat Med 14:39–44PubMedPubMedCentral
75.
Zurück zum Zitat Hill KP (2015) Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: a clinical review. JAMA 313:2474–2483PubMed Hill KP (2015) Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: a clinical review. JAMA 313:2474–2483PubMed
76.
Zurück zum Zitat Hockenberry MJ, McCarthy K, Taylor O, Scarberry M, Franklin Q, Louis CU, Torres L (2011) Managing painful procedures in children with cancer. J Pediatr Hematol Oncol 33:119–127PubMed Hockenberry MJ, McCarthy K, Taylor O, Scarberry M, Franklin Q, Louis CU, Torres L (2011) Managing painful procedures in children with cancer. J Pediatr Hematol Oncol 33:119–127PubMed
78.
Zurück zum Zitat Howard RF (2003) Current status of pain management in children. JAMA 290:2464–2469PubMed Howard RF (2003) Current status of pain management in children. JAMA 290:2464–2469PubMed
79.
Zurück zum Zitat Huguet A, Miro J (2008) The severity of chronic pediatric pain: an epidemiological study. J Pain 9:226–236PubMed Huguet A, Miro J (2008) The severity of chronic pediatric pain: an epidemiological study. J Pain 9:226–236PubMed
80.
Zurück zum Zitat Hunt K, Ernst E (2011) The evidence-base for complementary medicine in children: a critical overview of systematic reviews. Arch Dis Child 96:769–776PubMed Hunt K, Ernst E (2011) The evidence-base for complementary medicine in children: a critical overview of systematic reviews. Arch Dis Child 96:769–776PubMed
83.
Zurück zum Zitat Jerstad SJ, Boutelle KN, Ness KK, Stice E (2010) Prospective reciprocal relations between physical activity and depression in female adolescents. J Consult Clin Psychol 78:268–272PubMedPubMedCentral Jerstad SJ, Boutelle KN, Ness KK, Stice E (2010) Prospective reciprocal relations between physical activity and depression in female adolescents. J Consult Clin Psychol 78:268–272PubMedPubMedCentral
85.
Zurück zum Zitat Kajiume T, Sera Y, Nakanuno R, Ogura T, Karakawa S, Kobayakawa M, Taguchi S, Oshita K, Kawaguchi H, Sato T, Kobayashi M (2012) Continuous intravenous infusion of ketamine and lidocaine as adjuvant analgesics in a 5-year-old patient with neuropathic cancer pain. J Palliat Med 15:719–722PubMed Kajiume T, Sera Y, Nakanuno R, Ogura T, Karakawa S, Kobayakawa M, Taguchi S, Oshita K, Kawaguchi H, Sato T, Kobayashi M (2012) Continuous intravenous infusion of ketamine and lidocaine as adjuvant analgesics in a 5-year-old patient with neuropathic cancer pain. J Palliat Med 15:719–722PubMed
86.
Zurück zum Zitat Karlson K, Darcy L, Enskär K (2016) The use of restraint is never supportive (poster). Nordic Society of Pediatric Hematology/Oncology (NOPHO) 34th Annual meeting 2016 and 11th Biannual Meeting of Nordic Society of Pediatric Oncology Nurses (NOBOS), Reykjavik Karlson K, Darcy L, Enskär K (2016) The use of restraint is never supportive (poster). Nordic Society of Pediatric Hematology/Oncology (NOPHO) 34th Annual meeting 2016 and 11th Biannual Meeting of Nordic Society of Pediatric Oncology Nurses (NOBOS), Reykjavik
87.
Zurück zum Zitat Kelly LE, Rieder M, van den Anker J, Malkin B, Ross C, Neely MN, Carleton B, Hayden MR, Madadi P, Koren G (2012) More codeine fatalities after tonsillectomy in North American children. Pediatrics 129:e1343–e1347PubMed Kelly LE, Rieder M, van den Anker J, Malkin B, Ross C, Neely MN, Carleton B, Hayden MR, Madadi P, Koren G (2012) More codeine fatalities after tonsillectomy in North American children. Pediatrics 129:e1343–e1347PubMed
88.
Zurück zum Zitat Kemani MK, Kanstrup M, Jordan A, Caes L, Gauntlett-Gilbert J (2018) Evaluation of an intensive interdisciplinary pain treatment based on acceptance and commitment therapy for adolescents with chronic pain and their parents: a nonrandomized clinical trial. J Pediatr Psychol 43:981–994PubMed Kemani MK, Kanstrup M, Jordan A, Caes L, Gauntlett-Gilbert J (2018) Evaluation of an intensive interdisciplinary pain treatment based on acceptance and commitment therapy for adolescents with chronic pain and their parents: a nonrandomized clinical trial. J Pediatr Psychol 43:981–994PubMed
89.
Zurück zum Zitat Kennedy A, Basket M, Sheedy K (2011) Vaccine attitudes, concerns, and information sources reported by parents of young children: results from the 2009 HealthStyles survey. Pediatrics 127((suppl 1):S92–S99PubMed Kennedy A, Basket M, Sheedy K (2011) Vaccine attitudes, concerns, and information sources reported by parents of young children: results from the 2009 HealthStyles survey. Pediatrics 127((suppl 1):S92–S99PubMed
90.
Zurück zum Zitat King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, MacDonald AJ (2011) The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain 152:2729–2738PubMed King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, MacDonald AJ (2011) The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain 152:2729–2738PubMed
91.
Zurück zum Zitat Kohen DP, Olness KN (2011) Hypnosis and hypnotherapy with children. Routledge, New York Kohen DP, Olness KN (2011) Hypnosis and hypnotherapy with children. Routledge, New York
92.
Zurück zum Zitat Koren G, Cairns J, Chitayat D, Gaedigk A, Leeder SJ (2006) Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother. Lancet 368:704PubMed Koren G, Cairns J, Chitayat D, Gaedigk A, Leeder SJ (2006) Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother. Lancet 368:704PubMed
93.
Zurück zum Zitat Kovacic K, Hainsworth K, Sood M, Chelimsky G, Unteutsch R, Nugent M, Simpson P, Miranda A (2017) Neurostimulation for abdominal pain-related functional gastrointestinal disorders in adolescents: a randomised, double-blind, sham-controlled trial. Lancet Gastroenterol Hepatol 2:727–737PubMed Kovacic K, Hainsworth K, Sood M, Chelimsky G, Unteutsch R, Nugent M, Simpson P, Miranda A (2017) Neurostimulation for abdominal pain-related functional gastrointestinal disorders in adolescents: a randomised, double-blind, sham-controlled trial. Lancet Gastroenterol Hepatol 2:727–737PubMed
94.
Zurück zum Zitat Kuttner L, Friedrichsdorf SJ (2013) Hypnosis and palliative care. Therapeutic hypnosis with children and adolescents. Bethel, Crown House Publishing Limited, S 491–509 Kuttner L, Friedrichsdorf SJ (2013) Hypnosis and palliative care. Therapeutic hypnosis with children and adolescents. Bethel, Crown House Publishing Limited, S 491–509
95.
Zurück zum Zitat Lacson JC, Carroll JD, Tuazon E, Castelao EJ, Bernstein L, Cortessis VK (2012) Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk. Cancer 118:5374–5383PubMed Lacson JC, Carroll JD, Tuazon E, Castelao EJ, Bernstein L, Cortessis VK (2012) Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk. Cancer 118:5374–5383PubMed
96.
Zurück zum Zitat Law EF, Fisher E, Howard WJ, Levy R, Ritterband L, Palermo TM (2017) Longitudinal change in parent and child functioning after internet-delivered cognitive-behavioral therapy for chronic pain. Pain 158:1992–2000PubMedPubMedCentral Law EF, Fisher E, Howard WJ, Levy R, Ritterband L, Palermo TM (2017) Longitudinal change in parent and child functioning after internet-delivered cognitive-behavioral therapy for chronic pain. Pain 158:1992–2000PubMedPubMedCentral
98.
Zurück zum Zitat Lee BH, Scharff L, Sethna NF, McCarthy CF, Scott-Sutherland J, Shea AM, Sullivan P, Meier P, Zurakowski D, Masek BJ, Berde CB (2002) Physical therapy and cognitive-behavioral treatment for complex regional pain syndromes. J Pediatr 141:135–140PubMed Lee BH, Scharff L, Sethna NF, McCarthy CF, Scott-Sutherland J, Shea AM, Sullivan P, Meier P, Zurakowski D, Masek BJ, Berde CB (2002) Physical therapy and cognitive-behavioral treatment for complex regional pain syndromes. J Pediatr 141:135–140PubMed
99.
Zurück zum Zitat Levy RL, Langer SL, Walker LS, Romano JM, Christie DL, Youssef N, DuPen MM, Feld AD, Ballard SA, Welsh EM, Jeffery RW, Young M, Coffey MJ, Whitehead WE (2010) Cognitive-behavioral therapy for children with functional abdominal pain and their parents decreases pain and other symptoms. Am J Gastroenterol 105:946–956PubMedPubMedCentral Levy RL, Langer SL, Walker LS, Romano JM, Christie DL, Youssef N, DuPen MM, Feld AD, Ballard SA, Welsh EM, Jeffery RW, Young M, Coffey MJ, Whitehead WE (2010) Cognitive-behavioral therapy for children with functional abdominal pain and their parents decreases pain and other symptoms. Am J Gastroenterol 105:946–956PubMedPubMedCentral
100.
Zurück zum Zitat Lifland BE, Mangione-Smith R, Palermo TM, Rabbitts JA (2018) Agreement between parent proxy report and child self-report of pain intensity and health-related quality of life after surgery. Acad Pediatr 18:376–383PubMed Lifland BE, Mangione-Smith R, Palermo TM, Rabbitts JA (2018) Agreement between parent proxy report and child self-report of pain intensity and health-related quality of life after surgery. Acad Pediatr 18:376–383PubMed
101.
Zurück zum Zitat Livingston M, Lawell M, McAllister N (2017) Successful use of nitrous oxide during lumbar punctures: a call for nitrous oxide in pediatric oncology clinics. Pediatr Blood Cancer 64:e26610 Livingston M, Lawell M, McAllister N (2017) Successful use of nitrous oxide during lumbar punctures: a call for nitrous oxide in pediatric oncology clinics. Pediatr Blood Cancer 64:e26610
102.
Zurück zum Zitat Logan DE, Carpino EA, Chiang G, Condon M, Firn E, Gaughan VJ, Hogan M, Leslie DS, Olson K, Sager S, Sethna N, Simons LE, Zurakowski D, Berde CB (2012) A day-hospital approach to treatment of pediatric complex regional pain syndrome: initial functional outcomes. Clin J Pain 28:766–774PubMed Logan DE, Carpino EA, Chiang G, Condon M, Firn E, Gaughan VJ, Hogan M, Leslie DS, Olson K, Sager S, Sethna N, Simons LE, Zurakowski D, Berde CB (2012) A day-hospital approach to treatment of pediatric complex regional pain syndrome: initial functional outcomes. Clin J Pain 28:766–774PubMed
103.
Zurück zum Zitat Lunoe MM, Drendel AL, Brousseau DC (2015) The use of the needle-free jet injection system with buffered lidocaine device does not change intravenous placement success in children in the emergency department. Acad Emerg Med 22:447–451PubMedPubMedCentral Lunoe MM, Drendel AL, Brousseau DC (2015) The use of the needle-free jet injection system with buffered lidocaine device does not change intravenous placement success in children in the emergency department. Acad Emerg Med 22:447–451PubMedPubMedCentral
104.
Zurück zum Zitat Lunoe MM, Drendel AL, Levas MN, Weisman SJ, Dasgupta M, Hoffmann RG, Brousseau DC (2015) A randomized clinical trial of jet-injected lidocaine to reduce venipuncture pain for young children. Ann Emerg Med 66:466–474PubMedPubMedCentral Lunoe MM, Drendel AL, Levas MN, Weisman SJ, Dasgupta M, Hoffmann RG, Brousseau DC (2015) A randomized clinical trial of jet-injected lidocaine to reduce venipuncture pain for young children. Ann Emerg Med 66:466–474PubMedPubMedCentral
105.
Zurück zum Zitat Lynch-Jordan AM, Sil S, Peugh J, Cunningham N, Kashikar-Zuck S, Goldschneider KR (2014) Differential changes in functional disability and pain intensity over the course of psychological treatment for children with chronic pain. Pain 155:1955–1961PubMedPubMedCentral Lynch-Jordan AM, Sil S, Peugh J, Cunningham N, Kashikar-Zuck S, Goldschneider KR (2014) Differential changes in functional disability and pain intensity over the course of psychological treatment for children with chronic pain. Pain 155:1955–1961PubMedPubMedCentral
106.
Zurück zum Zitat Massey GV, Pedigo S, Dunn NL, Grossman NJ, Russell EC (2002) Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient. J Pediatr Hematol Oncol 24:566–568PubMed Massey GV, Pedigo S, Dunn NL, Grossman NJ, Russell EC (2002) Continuous lidocaine infusion for the relief of refractory malignant pain in a terminally ill pediatric cancer patient. J Pediatr Hematol Oncol 24:566–568PubMed
107.
Zurück zum Zitat Maynard CS, Amari A, Wieczorek B, Christensen JR, Slifer KJ (2010) Interdisciplinary behavioral rehabilitation of pediatric pain-associated disability: retrospective review of an inpatient treatment protocol. J Pediatr Psychol 35:128–137PubMed Maynard CS, Amari A, Wieczorek B, Christensen JR, Slifer KJ (2010) Interdisciplinary behavioral rehabilitation of pediatric pain-associated disability: retrospective review of an inpatient treatment protocol. J Pediatr Psychol 35:128–137PubMed
108.
Zurück zum Zitat McMurtry CM, Pillai Riddell R, Taddio A, Racine N, Asmundson GJ, Noel M, Chambers CT, Shah V, HelpinKids, Adults T (2015) Far from “just a poke”: common painful needle procedures and the development of needle fear. Clin J Pain 31(10 suppl):S3–S11PubMedPubMedCentral McMurtry CM, Pillai Riddell R, Taddio A, Racine N, Asmundson GJ, Noel M, Chambers CT, Shah V, HelpinKids, Adults T (2015) Far from “just a poke”: common painful needle procedures and the development of needle fear. Clin J Pain 31(10 suppl):S3–S11PubMedPubMedCentral
109.
Zurück zum Zitat McMurtry CM, Taddio A, Noel M, Antony MM, Chambers CT, Asmundson GJ, Pillai Riddell R, Shah V, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin S, Bowles S, Halpert C, Ipp M, Rieder MJ, Robson K, Uleryk E, Votta Bleeker E, Dubey V, Hanrahan A, Lockett D, Scott J (2016) Exposure-based Interventions for the management of individuals with high levels of needle fear across the lifespan: a clinical practice guideline and call for further research. Cogn Behav Ther 45:217–235PubMedPubMedCentral McMurtry CM, Taddio A, Noel M, Antony MM, Chambers CT, Asmundson GJ, Pillai Riddell R, Shah V, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin S, Bowles S, Halpert C, Ipp M, Rieder MJ, Robson K, Uleryk E, Votta Bleeker E, Dubey V, Hanrahan A, Lockett D, Scott J (2016) Exposure-based Interventions for the management of individuals with high levels of needle fear across the lifespan: a clinical practice guideline and call for further research. Cogn Behav Ther 45:217–235PubMedPubMedCentral
110.
Zurück zum Zitat Meier MH, Caspi A, Ambler A, Harrington H, Houts R, Keefe RS, McDonald K, Ward A, Poulton R, Moffitt TE (2012) Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A 109:E2657–E2664PubMedPubMedCentral Meier MH, Caspi A, Ambler A, Harrington H, Houts R, Keefe RS, McDonald K, Ward A, Poulton R, Moffitt TE (2012) Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A 109:E2657–E2664PubMedPubMedCentral
111.
Zurück zum Zitat Meier MH, Hall W, Caspi A, Belsky DW, Cerda M, Harrington HL, Houts R, Poulton R, Moffitt TE (2016) Which adolescents develop persistent substance dependence in adulthood? Using population-representative longitudinal data to inform universal risk assessment. Psychol Med 46:877–889PubMed Meier MH, Hall W, Caspi A, Belsky DW, Cerda M, Harrington HL, Houts R, Poulton R, Moffitt TE (2016) Which adolescents develop persistent substance dependence in adulthood? Using population-representative longitudinal data to inform universal risk assessment. Psychol Med 46:877–889PubMed
112.
Zurück zum Zitat Moffitt TE, Meier MH, Caspi A, Poulton R (2013) Reply to Rogeberg and Daly: no evidence that socioeconomic status or personality differences confound the association between cannabis use and IQ decline. Proc Natl Acad Sci U S A 110:E980–E982PubMedPubMedCentral Moffitt TE, Meier MH, Caspi A, Poulton R (2013) Reply to Rogeberg and Daly: no evidence that socioeconomic status or personality differences confound the association between cannabis use and IQ decline. Proc Natl Acad Sci U S A 110:E980–E982PubMedPubMedCentral
113.
Zurück zum Zitat Moore RA, Derry S, Straube S, Ireson-Paine J, Wiffen PJ (2014) Faster, higher, stronger? Evidence for formulation and efficacy for ibuprofen in acute pain. Pain 155:14–21PubMed Moore RA, Derry S, Straube S, Ireson-Paine J, Wiffen PJ (2014) Faster, higher, stronger? Evidence for formulation and efficacy for ibuprofen in acute pain. Pain 155:14–21PubMed
114.
Zurück zum Zitat Nikanne E, Kokki H, Tuovinen K (1999) Postoperative pain after adenoidectomy in children. Br J Anaesth 82:886–889PubMed Nikanne E, Kokki H, Tuovinen K (1999) Postoperative pain after adenoidectomy in children. Br J Anaesth 82:886–889PubMed
115.
Zurück zum Zitat Nissen SE, Yeomans ND, Solomon DH, Luscher TF, Libby P, Husni ME, Graham DY, Borer JS, Wisniewski LM, Wolski KE, Wang Q, Menon V, Ruschitzka F, Gaffney M, Beckerman B, Berger MF, Bao W, Lincoff AM, Investigators PT (2016) Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N Engl J Med 375:2519–2529PubMed Nissen SE, Yeomans ND, Solomon DH, Luscher TF, Libby P, Husni ME, Graham DY, Borer JS, Wisniewski LM, Wolski KE, Wang Q, Menon V, Ruschitzka F, Gaffney M, Beckerman B, Berger MF, Bao W, Lincoff AM, Investigators PT (2016) Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N Engl J Med 375:2519–2529PubMed
116.
Zurück zum Zitat Odell S, Logan DE (2013) Pediatric pain management: the multidisciplinary approach. J Pain Res 6:785–790PubMedPubMedCentral Odell S, Logan DE (2013) Pediatric pain management: the multidisciplinary approach. J Pain Res 6:785–790PubMedPubMedCentral
117.
Zurück zum Zitat Palermo TM, Scher MS (2001) Treatment of functional impairment in severe somatoform pain disorder: a case example. J Pediatr Psychol 26:429–434PubMed Palermo TM, Scher MS (2001) Treatment of functional impairment in severe somatoform pain disorder: a case example. J Pediatr Psychol 26:429–434PubMed
118.
Zurück zum Zitat Palermo TM, Eccleston C, Lewandowski AS, Williams AC, Morley S (2010) Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents: an updated meta-analytic review. Pain 148:387–397PubMed Palermo TM, Eccleston C, Lewandowski AS, Williams AC, Morley S (2010) Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents: an updated meta-analytic review. Pain 148:387–397PubMed
119.
Zurück zum Zitat Palermo TM, Valrie CR, Karlson CW (2014) Family and parent influences on pediatric chronic pain: a developmental perspective. Am Psychol 69:142–152PubMedPubMedCentral Palermo TM, Valrie CR, Karlson CW (2014) Family and parent influences on pediatric chronic pain: a developmental perspective. Am Psychol 69:142–152PubMedPubMedCentral
120.
Zurück zum Zitat Palermo TM, Law EF, Fales J, Bromberg MH, Jessen-Fiddick T, Tai G (2016) Internet-delivered cognitive-behavioral treatment for adolescents with chronic pain and their parents: a randomized controlled multicenter trial. Pain 157:174–185PubMedPubMedCentral Palermo TM, Law EF, Fales J, Bromberg MH, Jessen-Fiddick T, Tai G (2016) Internet-delivered cognitive-behavioral treatment for adolescents with chronic pain and their parents: a randomized controlled multicenter trial. Pain 157:174–185PubMedPubMedCentral
121.
Zurück zum Zitat Palermo T (2012) Cognitive-behavioral therapy for chronic pain in children and adolescents. Oxford University Press, New York Palermo T (2012) Cognitive-behavioral therapy for chronic pain in children and adolescents. Oxford University Press, New York
122.
Zurück zum Zitat Pedersen RS, Bayat A, Steen NP, Jacobsson ML (2013) Nitrous oxide provides safe and effective analgesia for minor paediatric procedures—a systematic review. Dan Med J 60:A4627PubMed Pedersen RS, Bayat A, Steen NP, Jacobsson ML (2013) Nitrous oxide provides safe and effective analgesia for minor paediatric procedures—a systematic review. Dan Med J 60:A4627PubMed
124.
Zurück zum Zitat Peixoto RD, Hawley P (2015) Intravenous lidocaine for cancer pain without electrocardiographic monitoring: a retrospective review. J Palliat Med 18:373–377PubMed Peixoto RD, Hawley P (2015) Intravenous lidocaine for cancer pain without electrocardiographic monitoring: a retrospective review. J Palliat Med 18:373–377PubMed
125.
Zurück zum Zitat Peters ML, Smeets E, Feijge M, van Breukelen G, Andersson G, Buhrman M, Linton SJ (2017) Happy despite pain: a randomized controlled trial of an 8‑week internet-delivered positive psychology intervention for enhancing well-being in patients with chronic pain. Clin J Pain 33:962–975PubMedPubMedCentral Peters ML, Smeets E, Feijge M, van Breukelen G, Andersson G, Buhrman M, Linton SJ (2017) Happy despite pain: a randomized controlled trial of an 8‑week internet-delivered positive psychology intervention for enhancing well-being in patients with chronic pain. Clin J Pain 33:962–975PubMedPubMedCentral
126.
Zurück zum Zitat Pielech M, Vowles KE, Wicksell R (2017) Acceptance and commitment therapy for pediatric chronic pain: theory and application. Children 4:E10PubMed Pielech M, Vowles KE, Wicksell R (2017) Acceptance and commitment therapy for pediatric chronic pain: theory and application. Children 4:E10PubMed
127.
Zurück zum Zitat Postier AC, Eull D, Schulz C, Fitzgerald M, Symalla B, Watson D, Goertzen L, Friedrichsdorf SJ (2018) Pain experience in a US children’s hospital: a point prevalence survey undertaken after the implementation of a system-wide protocol to eliminate or decrease pain caused by needles. Hosp Pediatr 8:515–523PubMed Postier AC, Eull D, Schulz C, Fitzgerald M, Symalla B, Watson D, Goertzen L, Friedrichsdorf SJ (2018) Pain experience in a US children’s hospital: a point prevalence survey undertaken after the implementation of a system-wide protocol to eliminate or decrease pain caused by needles. Hosp Pediatr 8:515–523PubMed
128.
Zurück zum Zitat Ramsey LH, Karlson CW, Collier AB (2017) Mirror therapy for phantom limb pain in a 7-year-old male with osteosarcoma. J Pain Symptom Manage 53:e5–e7PubMed Ramsey LH, Karlson CW, Collier AB (2017) Mirror therapy for phantom limb pain in a 7-year-old male with osteosarcoma. J Pain Symptom Manage 53:e5–e7PubMed
129.
Zurück zum Zitat Reynolds N, Mrug S, Guion K (2013) Spiritual coping and psychosocial adjustment of adolescents with chronic illness: the role of cognitive attributions, age, and disease group. J Adolesc Health 52:559–565PubMed Reynolds N, Mrug S, Guion K (2013) Spiritual coping and psychosocial adjustment of adolescents with chronic illness: the role of cognitive attributions, age, and disease group. J Adolesc Health 52:559–565PubMed
130.
Zurück zum Zitat Richardson J, Smith JE, McCall G, Pilkington K (2006) Hypnosis for procedure-related pain and distress in pediatric cancer patients: a systematic review of effectiveness and methodology related to hypnosis interventions. J Pain Symptom Manage 31:70–84PubMed Richardson J, Smith JE, McCall G, Pilkington K (2006) Hypnosis for procedure-related pain and distress in pediatric cancer patients: a systematic review of effectiveness and methodology related to hypnosis interventions. J Pain Symptom Manage 31:70–84PubMed
132.
Zurück zum Zitat Roofthooft DW, Simons SH, Anand KJ, Tibboel D, van Dijk M (2014) Eight years later, are we still hurting newborn infants? Neonatology 105:218–226PubMed Roofthooft DW, Simons SH, Anand KJ, Tibboel D, van Dijk M (2014) Eight years later, are we still hurting newborn infants? Neonatology 105:218–226PubMed
133.
Zurück zum Zitat Rork JF, Berde CB, Goldstein RD (2013) Regional anesthesia approaches to pain management in pediatric palliative care: a review of current knowledge. J Pain Symptom Manage 46:859–873PubMed Rork JF, Berde CB, Goldstein RD (2013) Regional anesthesia approaches to pain management in pediatric palliative care: a review of current knowledge. J Pain Symptom Manage 46:859–873PubMed
134.
Zurück zum Zitat Schechter NL, Allen DA, Hanson K (1986) Status of pediatric pain control: a comparison of hospital analgesic usage in children and adults. Pediatrics 77:11–15PubMed Schechter NL, Allen DA, Hanson K (1986) Status of pediatric pain control: a comparison of hospital analgesic usage in children and adults. Pediatrics 77:11–15PubMed
135.
Zurück zum Zitat Schreiber S, Ronfani L, Chiaffoni GP, Matarazzo L, Minute M, Panontin E, Poropat F, Germani C, Barbi E (2013) Does EMLA cream application interfere with the success of venipuncture or venous cannulation? A prospective multicenter observational study. Eur J Pediatr 172:265–268PubMed Schreiber S, Ronfani L, Chiaffoni GP, Matarazzo L, Minute M, Panontin E, Poropat F, Germani C, Barbi E (2013) Does EMLA cream application interfere with the success of venipuncture or venous cannulation? A prospective multicenter observational study. Eur J Pediatr 172:265–268PubMed
136.
Zurück zum Zitat Seah DSE, Herschtal A, Tran H, Thakerar A, Fullerton S (2017) Subcutaneous lidocaine infusion for pain in patients with cancer. J Palliat Med 20:667–671PubMed Seah DSE, Herschtal A, Tran H, Thakerar A, Fullerton S (2017) Subcutaneous lidocaine infusion for pain in patients with cancer. J Palliat Med 20:667–671PubMed
137.
Zurück zum Zitat Sen IM, Sen RK (2012) Regional anesthesia for lower limb burn wound debridements. Arch Trauma Res 1:135–136PubMedPubMedCentral Sen IM, Sen RK (2012) Regional anesthesia for lower limb burn wound debridements. Arch Trauma Res 1:135–136PubMedPubMedCentral
139.
Zurück zum Zitat Shank ES, Martyn JA, Donelan MB, Perrone A, Firth PG, Driscoll DN (2016) Ultrasound-guided regional anesthesia for pediatric burn reconstructive surgery: a prospective study. J Burn Care Res 37:e213–e217PubMed Shank ES, Martyn JA, Donelan MB, Perrone A, Firth PG, Driscoll DN (2016) Ultrasound-guided regional anesthesia for pediatric burn reconstructive surgery: a prospective study. J Burn Care Res 37:e213–e217PubMed
140.
Zurück zum Zitat Sherry DD, Wallace CA, Kelley C, Kidder M, Sapp L (1999) Short- and long-term outcomes of children with complex regional pain syndrome type I treated with exercise therapy. Clin J Pain 15:218–223PubMed Sherry DD, Wallace CA, Kelley C, Kidder M, Sapp L (1999) Short- and long-term outcomes of children with complex regional pain syndrome type I treated with exercise therapy. Clin J Pain 15:218–223PubMed
141.
Zurück zum Zitat Shomaker K, Dutton S, Mark M (2015) Pain prevalence and treatment patterns in a US children’s hospital. Hosp Pediatr 5:363–370PubMed Shomaker K, Dutton S, Mark M (2015) Pain prevalence and treatment patterns in a US children’s hospital. Hosp Pediatr 5:363–370PubMed
142.
Zurück zum Zitat Simons LE, Smith A, Ibagon C, Coakley R, Logan DE, Schechter N, Borsook D, Hill JC (2015) Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints. Pain 156:1511–1518PubMedPubMedCentral Simons LE, Smith A, Ibagon C, Coakley R, Logan DE, Schechter N, Borsook D, Hill JC (2015) Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints. Pain 156:1511–1518PubMedPubMedCentral
143.
Zurück zum Zitat Simons LE, Lewandowski HA, Phelps E, Wilson AC (2019) PRISM: a brief screening tool to identify risk in parents of youth with chronic pain. Pain 160:367–374PubMed Simons LE, Lewandowski HA, Phelps E, Wilson AC (2019) PRISM: a brief screening tool to identify risk in parents of youth with chronic pain. Pain 160:367–374PubMed
144.
Zurück zum Zitat Stanford EA, Chambers CT, Biesanz JC, Chen E (2008) The frequency, trajectories and predictors of adolescent recurrent pain: a population-based approach. Pain 138:11–21PubMed Stanford EA, Chambers CT, Biesanz JC, Chen E (2008) The frequency, trajectories and predictors of adolescent recurrent pain: a population-based approach. Pain 138:11–21PubMed
145.
Zurück zum Zitat Stevens BJ, Harrison D, Rashotte J, Yamada J, Abbott LK, Coburn G, Stinson J, Le May S (2012) Pain assessment and intensity in hospitalized children in Canada. J Pain 13:857–865PubMed Stevens BJ, Harrison D, Rashotte J, Yamada J, Abbott LK, Coburn G, Stinson J, Le May S (2012) Pain assessment and intensity in hospitalized children in Canada. J Pain 13:857–865PubMed
146.
Zurück zum Zitat Stevens B, Yamada J, Ohlsson A, Haliburton S, Shorkey A (2016) Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev 7:CD1069PubMed Stevens B, Yamada J, Ohlsson A, Haliburton S, Shorkey A (2016) Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev 7:CD1069PubMed
147.
Zurück zum Zitat Stevens B, Yamada J, Campbell-Yeo M, Gibbins S, Harrison D, Dionne K, Taddio A, McNair C, Willan A, Ballantyne M, Widger K, Sidani S, Estabrooks C, Synnes A, Squires J, Victor C, Riahi S (2018) The minimally effective dose of sucrose for procedural pain relief in neonates: a randomized controlled trial. BMC Pediatr 18:85PubMedPubMedCentral Stevens B, Yamada J, Campbell-Yeo M, Gibbins S, Harrison D, Dionne K, Taddio A, McNair C, Willan A, Ballantyne M, Widger K, Sidani S, Estabrooks C, Synnes A, Squires J, Victor C, Riahi S (2018) The minimally effective dose of sucrose for procedural pain relief in neonates: a randomized controlled trial. BMC Pediatr 18:85PubMedPubMedCentral
148.
Zurück zum Zitat Stubberud A, Varkey E, McCrory DC, Pedersen SA, Linde M (2016) Biofeedback as prophylaxis for pediatric migraine: a meta-analysis. Pediatrics 138:e20160675PubMed Stubberud A, Varkey E, McCrory DC, Pedersen SA, Linde M (2016) Biofeedback as prophylaxis for pediatric migraine: a meta-analysis. Pediatrics 138:e20160675PubMed
149.
Zurück zum Zitat Taddio A, Katz J, Ilersich AL, Koren G (1997) Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 349:599–603PubMed Taddio A, Katz J, Ilersich AL, Koren G (1997) Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 349:599–603PubMed
150.
Zurück zum Zitat Taddio A, Chambers CT, Halperin SA, Ipp M, Lockett D, Rieder MJ, Shah V (2009) Inadequate pain management during routine childhood immunizations: the nerve of it. Clin Ther 31(suppl 2):S152–S167PubMed Taddio A, Chambers CT, Halperin SA, Ipp M, Lockett D, Rieder MJ, Shah V (2009) Inadequate pain management during routine childhood immunizations: the nerve of it. Clin Ther 31(suppl 2):S152–S167PubMed
151.
Zurück zum Zitat Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V (2010) Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline. Cmaj 182:E843–855PubMedPubMedCentral Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V (2010) Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline. Cmaj 182:E843–855PubMedPubMedCentral
152.
Zurück zum Zitat Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V (2010) Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline (summary). Cmaj 182:1989–1995PubMedPubMedCentral Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V (2010) Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline (summary). Cmaj 182:1989–1995PubMedPubMedCentral
153.
Zurück zum Zitat Taddio A, Ipp M, Thivakaran S, Jamal A, Parikh C, Smart S, Sovran J, Stephens D, Katz J (2012) Survey of the prevalence of immunization non-compliance due to needle fears in children and adults. Vaccine 30:4807–4812PubMed Taddio A, Ipp M, Thivakaran S, Jamal A, Parikh C, Smart S, Sovran J, Stephens D, Katz J (2012) Survey of the prevalence of immunization non-compliance due to needle fears in children and adults. Vaccine 30:4807–4812PubMed
154.
Zurück zum Zitat Taddio A, McMurtry CM, Shah V, Riddell RP, Chambers CT, Noel M, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin SA, Bowles S, Halpert C, Ipp M, Asmundson GJ, Rieder MJ, Robson K, Uleryk E, Antony MM, Dubey V, Hanrahan A, Lockett D, Scott J, Votta Bleeker E, HelpinKids, Adults (2015) Reducing pain during vaccine injections: clinical practice guideline. CMAJ 187:975–982PubMedPubMedCentral Taddio A, McMurtry CM, Shah V, Riddell RP, Chambers CT, Noel M, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin SA, Bowles S, Halpert C, Ipp M, Asmundson GJ, Rieder MJ, Robson K, Uleryk E, Antony MM, Dubey V, Hanrahan A, Lockett D, Scott J, Votta Bleeker E, HelpinKids, Adults (2015) Reducing pain during vaccine injections: clinical practice guideline. CMAJ 187:975–982PubMedPubMedCentral
155.
Zurück zum Zitat Taddio A, Parikh C, Yoon EW, Sgro M, Singh H, Habtom E, Ilersich AF, Pillai Riddell R, Shah V (2015) Impact of parent-directed education on parental use of pain treatments during routine infant vaccinations: a cluster randomized trial. Pain 156:185–191PubMed Taddio A, Parikh C, Yoon EW, Sgro M, Singh H, Habtom E, Ilersich AF, Pillai Riddell R, Shah V (2015) Impact of parent-directed education on parental use of pain treatments during routine infant vaccinations: a cluster randomized trial. Pain 156:185–191PubMed
156.
Zurück zum Zitat Taddio A, Shah V, McMurtry CM, MacDonald NE, Ipp M, Riddell RP, Noel M, Chambers CT, HelpinKids, Adults (2015) Procedural and physical interventions for vaccine injections: systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 31(10 suppl):S20–S37PubMedPubMedCentral Taddio A, Shah V, McMurtry CM, MacDonald NE, Ipp M, Riddell RP, Noel M, Chambers CT, HelpinKids, Adults (2015) Procedural and physical interventions for vaccine injections: systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 31(10 suppl):S20–S37PubMedPubMedCentral
157.
Zurück zum Zitat Taddio A, Pillai Riddell R, Ipp M, Moss S, Baker S, Tolkin J, Malini D, Feerasta S, Govan P, Fletcher E, Wong H, McNair C, Mithal P, Stephens D (2017) Relative effectiveness of additive pain interventions during vaccination in infants. CMAJ 189:E227–E234PubMedPubMedCentral Taddio A, Pillai Riddell R, Ipp M, Moss S, Baker S, Tolkin J, Malini D, Feerasta S, Govan P, Fletcher E, Wong H, McNair C, Mithal P, Stephens D (2017) Relative effectiveness of additive pain interventions during vaccination in infants. CMAJ 189:E227–E234PubMedPubMedCentral
158.
Zurück zum Zitat Tang WX, Zhang LF, Ai YQ, Li ZS (2018) Efficacy of Internet-delivered cognitive-behavioral therapy for the management of chronic pain in children and adolescents: a systematic review and meta-analysis. Medicine 97:e12061PubMedPubMedCentral Tang WX, Zhang LF, Ai YQ, Li ZS (2018) Efficacy of Internet-delivered cognitive-behavioral therapy for the management of chronic pain in children and adolescents: a systematic review and meta-analysis. Medicine 97:e12061PubMedPubMedCentral
159.
Zurück zum Zitat Taylor EM, Boyer K, Campbell FA (2008) Pain in hospitalized children: a prospective cross-sectional survey of pain prevalence, intensity, assessment and management in a Canadian pediatric teaching hospital. Pain Res Manag 13:25–32PubMedPubMedCentral Taylor EM, Boyer K, Campbell FA (2008) Pain in hospitalized children: a prospective cross-sectional survey of pain prevalence, intensity, assessment and management in a Canadian pediatric teaching hospital. Pain Res Manag 13:25–32PubMedPubMedCentral
160.
Zurück zum Zitat Teerawattananon C, Tantayakom P, Suwanawiboon B, Katchamart W (2017) Risk of perioperative bleeding related to highly selective cyclooxygenase‑2 inhibitors: a systematic review and meta-analysis. Semin Arthritis Rheum 46:520–528PubMed Teerawattananon C, Tantayakom P, Suwanawiboon B, Katchamart W (2017) Risk of perioperative bleeding related to highly selective cyclooxygenase‑2 inhibitors: a systematic review and meta-analysis. Semin Arthritis Rheum 46:520–528PubMed
161.
Zurück zum Zitat Tegethoff M, Belardi A, Stalujanis E, Meinlschmidt G (2015) Comorbidity of mental disorders and chronic pain: chronology of onset in adolescents of a National Representative Cohort. J Pain 16:1054–1064PubMed Tegethoff M, Belardi A, Stalujanis E, Meinlschmidt G (2015) Comorbidity of mental disorders and chronic pain: chronology of onset in adolescents of a National Representative Cohort. J Pain 16:1054–1064PubMed
162.
Zurück zum Zitat Tobias JD (2013) Applications of nitrous oxide for procedural sedation in the pediatric population. Pediatr Emerg Care 29:245–265PubMed Tobias JD (2013) Applications of nitrous oxide for procedural sedation in the pediatric population. Pediatr Emerg Care 29:245–265PubMed
164.
Zurück zum Zitat Trabert B, Sigurdson AJ, Sweeney AM, Strom SS, McGlynn KA (2011) Marijuana use and testicular germ cell tumors. Cancer 117:848–853PubMed Trabert B, Sigurdson AJ, Sweeney AM, Strom SS, McGlynn KA (2011) Marijuana use and testicular germ cell tumors. Cancer 117:848–853PubMed
165.
Zurück zum Zitat Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Kosek E, Lavand’homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JW, Wang SJ (2015) A classification of chronic pain for ICD-11. Pain 156:1003–1007PubMedPubMedCentral Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Kosek E, Lavand’homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JW, Wang SJ (2015) A classification of chronic pain for ICD-11. Pain 156:1003–1007PubMedPubMedCentral
166.
Zurück zum Zitat Turk D, Okifuji A (2001) Pain terms and taxonomies of pain. In: Bonica J, Loeser J, Chapman C, Turk D, Butler S (Hrsg) Bonica’s management of pain. Lippincott Williams & Wilkins, Philadelphia Turk D, Okifuji A (2001) Pain terms and taxonomies of pain. In: Bonica J, Loeser J, Chapman C, Turk D, Butler S (Hrsg) Bonica’s management of pain. Lippincott Williams & Wilkins, Philadelphia
167.
Zurück zum Zitat Twycross A, Collis S (2013) How well is acute pain in children managed? A snapshot in one English hospital. Pain Manag Nurs 14:e204–e215PubMed Twycross A, Collis S (2013) How well is acute pain in children managed? A snapshot in one English hospital. Pain Manag Nurs 14:e204–e215PubMed
168.
Zurück zum Zitat Uman LS, Birnie KA, Noel M, Parker JA, Chambers CT, McGrath PJ, Kisely SR (2013) Psychological interventions for needle-related procedural pain and distress in children and adolescents. Cochrane Database Syst Rev 10:CD5179 Uman LS, Birnie KA, Noel M, Parker JA, Chambers CT, McGrath PJ, Kisely SR (2013) Psychological interventions for needle-related procedural pain and distress in children and adolescents. Cochrane Database Syst Rev 10:CD5179
169.
Zurück zum Zitat Valeri BO, Ranger M, Chau CM, Cepeda IL, Synnes A, Linhares MB, Grunau RE (2016) Neonatal invasive procedures predict pain intensity at school age in children born very preterm. Clin J Pain 32:1086–1093PubMedPubMedCentral Valeri BO, Ranger M, Chau CM, Cepeda IL, Synnes A, Linhares MB, Grunau RE (2016) Neonatal invasive procedures predict pain intensity at school age in children born very preterm. Clin J Pain 32:1086–1093PubMedPubMedCentral
170.
Zurück zum Zitat Vas J, Santos-Rey K, Navarro-Pablo R, Modesto M, Aguilar I, Campos MA, Aguilar-Velasco JF, Romero M, Parraga P, Hervas V, Santamaria O, Marquez-Zurita C, Rivas-Ruiz F (2016) Acupuncture for fibromyalgia in primary care: a randomised controlled trial. Acupunct Med 34:257–266PubMed Vas J, Santos-Rey K, Navarro-Pablo R, Modesto M, Aguilar I, Campos MA, Aguilar-Velasco JF, Romero M, Parraga P, Hervas V, Santamaria O, Marquez-Zurita C, Rivas-Ruiz F (2016) Acupuncture for fibromyalgia in primary care: a randomised controlled trial. Acupunct Med 34:257–266PubMed
171.
Zurück zum Zitat Veehof MM, Trompetter HR, Bohlmeijer ET, Schreurs KM (2016) Acceptance- and mindfulness-based interventions for the treatment of chronic pain: a meta-analytic review. Cogn Behav Ther 45:5–31PubMed Veehof MM, Trompetter HR, Bohlmeijer ET, Schreurs KM (2016) Acceptance- and mindfulness-based interventions for the treatment of chronic pain: a meta-analytic review. Cogn Behav Ther 45:5–31PubMed
172.
Zurück zum Zitat Verkamp EK, Flowers SR, Lynch-Jordan AM, Taylor J, Ting TV, Kashikar-Zuck S (2013) A survey of conventional and complementary therapies used by youth with juvenile-onset fibromyalgia. Pain Manag Nurs 14:e244–e250PubMed Verkamp EK, Flowers SR, Lynch-Jordan AM, Taylor J, Ting TV, Kashikar-Zuck S (2013) A survey of conventional and complementary therapies used by youth with juvenile-onset fibromyalgia. Pain Manag Nurs 14:e244–e250PubMed
173.
Zurück zum Zitat Vervoort T, Logan DE, Goubert L, De Clercq B, Hublet A (2014) Severity of pediatric pain in relation to school-related functioning and teacher support: an epidemiological study among school-aged children and adolescents. Pain 155:1118–1127PubMed Vervoort T, Logan DE, Goubert L, De Clercq B, Hublet A (2014) Severity of pediatric pain in relation to school-related functioning and teacher support: an epidemiological study among school-aged children and adolescents. Pain 155:1118–1127PubMed
174.
Zurück zum Zitat Victoria NC, Murphy AZ (2016) Exposure to early life pain: long term consequences and contributing mechanisms. Curr Opin Behav Sci 7:61–68PubMedPubMedCentral Victoria NC, Murphy AZ (2016) Exposure to early life pain: long term consequences and contributing mechanisms. Curr Opin Behav Sci 7:61–68PubMedPubMedCentral
175.
Zurück zum Zitat Wallace MS, Lee J, Sorkin L, Dunn JS, Yaksh T, Yu A (1997) Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma—a report of a series. Anesth Analg 85:794–796PubMed Wallace MS, Lee J, Sorkin L, Dunn JS, Yaksh T, Yu A (1997) Intravenous lidocaine: effects on controlling pain after anti-GD2 antibody therapy in children with neuroblastoma—a report of a series. Anesth Analg 85:794–796PubMed
176.
Zurück zum Zitat Walther-Larsen S, Pedersen MT, Friis SM, Aagaard GB, Romsing J, Jeppesen EM, Friedrichsdorf SJ (2016) Pain prevalence in hospitalized children: a prospective cross-sectional survey in four Danish university hospitals. Acta Anaesthesiol Scand 61:328–337PubMed Walther-Larsen S, Pedersen MT, Friis SM, Aagaard GB, Romsing J, Jeppesen EM, Friedrichsdorf SJ (2016) Pain prevalence in hospitalized children: a prospective cross-sectional survey in four Danish university hospitals. Acta Anaesthesiol Scand 61:328–337PubMed
177.
Zurück zum Zitat World_Health_Organization (2012) WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses. WHO Press, Geneva World_Health_Organization (2012) WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses. WHO Press, Geneva
178.
Zurück zum Zitat Xiang A, Cheng K, Shen X, Xu P, Liu S (2017) The immediate analgesic effect of acupuncture for pain: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2017:3837194PubMedPubMedCentral Xiang A, Cheng K, Shen X, Xu P, Liu S (2017) The immediate analgesic effect of acupuncture for pain: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2017:3837194PubMedPubMedCentral
179.
Zurück zum Zitat Zhu LM, Stinson J, Palozzi L, Weingarten K, Hogan ME, Duong S, Carbajal R, Campbell FA, Taddio A (2012) Improvements in pain outcomes in a Canadian pediatric teaching hospital following implementation of a multifaceted knowledge translation initiative. Pain Res Manag 17:173–179PubMedPubMedCentral Zhu LM, Stinson J, Palozzi L, Weingarten K, Hogan ME, Duong S, Carbajal R, Campbell FA, Taddio A (2012) Improvements in pain outcomes in a Canadian pediatric teaching hospital following implementation of a multifaceted knowledge translation initiative. Pain Res Manag 17:173–179PubMedPubMedCentral
180.
Zurück zum Zitat Zier JL, Liu M (2011) Safety of high-concentration nitrous oxide by nasal mask for pediatric procedural sedation: experience with 7802 cases. Pediatr Emerg Care 27:1107–1112PubMed Zier JL, Liu M (2011) Safety of high-concentration nitrous oxide by nasal mask for pediatric procedural sedation: experience with 7802 cases. Pediatr Emerg Care 27:1107–1112PubMed
Metadaten
Titel
Pädiatrische Schmerztherapie und -prävention bei hospitalisierten Kindern
verfasst von
Stefan J. Friedrichsdorf
Liesbet Goubert
Publikationsdatum
18.12.2020
Verlag
Springer Medizin
Erschienen in
Der Schmerz / Ausgabe 3/2021
Print ISSN: 0932-433X
Elektronische ISSN: 1432-2129
DOI
https://doi.org/10.1007/s00482-020-00519-0

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