Erschienen in:
01.02.2014 | Editor’s Commentary
Searching for genomic answers to recurrent pregnancy loss—barking up the wrong tree?
verfasst von:
David F. Albertini
Erschienen in:
Journal of Assisted Reproduction and Genetics
|
Ausgabe 2/2014
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Excerpt
Several months ago I attended a seminar entitled “What does our genome encode?” To finally hear that the bulk of our genomes have uses in unpredictable ways was encouraging. After all, unlike most of the organisms that populate our planet, mammals in general and humans in particular have brought to the genomics discussion table a most perplexing and puzzling situation. While plants and invertebrates engage > 90 % of their genomes in protein-encoding genes and domains that regulate gene activity--with the balance ascribed to “junk DNA”--we humanoids have taken an apparently alternative tack by endowing a meager 2 % of our genomes as protein-encoding and designating the 98 % balance as junk! But what is one person’s junk may be turning into another’s gold. …