Skip to main content
Erschienen in: European Archives of Oto-Rhino-Laryngology 10/2019

15.07.2019 | Rhinology

Seasonal variations in chronic rhinosinusitis symptom burden may be explained by changes in mood

verfasst von: Rehab Talat, Katie M. Phillips, David S. Caradonna, Stacey T. Gray, Ahmad R. Sedaghat

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 10/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

There are many year-round modifiers of chronic rhinosinusitis (CRS). However, it is unknown whether there are seasonal variations in the sinonasal symptom burden of CRS.

Methods

This was a retrospective cross-sectional study of sinonasal symptom burden measured using the 22-item Sinonasal Outcome Test (SNOT-22) and its four associated nasal, sleep, ear/facial discomfort and emotional subdomains in 1028 individuals with CRS. The season (winter, spring, summer or fall) when the SNOT-22 was completed was recorded. Regressions, controlling for clinical and demographic characteristics, were performed to seek association between season of the year and SNOT-22 total and subdomain scores.

Results

The mean SNOT-22 scores were 37.4 for those individuals completing their SNOT-22 in the fall, 40.5 in the winter, 37.4 in the spring and 36.0 in the summer. There was a statistically significant association between higher SNOT-22 scores and completing the SNOT-22 in the wintertime (adjusted β = 4.08, 95% CI 0.74–7.42, p = 0.017). When seeking association between season and SNOT-22 subdomain scores, wintertime was associated only with higher emotional (adjusted β = 0.48, 95% CI 0.14–0.81, p = 0.006) and sleep (adjusted β = 2.23, 95% CI 0.54–3.91, p = 0.010) subdomain scores. Examining individual SNOT-22 items, these associations were due to more symptoms related to depressed mood (“sad”) and psychomotor retardation.

Conclusion

There are seasonal variations in symptom burden of CRS patients, independent of aeroallergen hypersensitivity, with the greatest increase in baseline CRS symptomatology during the winter. This finding was most strongly associated with increased emotional symptomatology and depressed mood.
Literatur
1.
Zurück zum Zitat Fokkens WJ, Lund VJ, Mullol J et al (2012) European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl 23:298 Fokkens WJ, Lund VJ, Mullol J et al (2012) European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl 23:298
2.
Zurück zum Zitat Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2016) Association of severity of chronic rhinosinusitis with degree of comorbid asthma control. Ann Allergy Asthma Immunol 117:651–654CrossRef Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2016) Association of severity of chronic rhinosinusitis with degree of comorbid asthma control. Ann Allergy Asthma Immunol 117:651–654CrossRef
3.
Zurück zum Zitat Rudmik L, Smith TL, Schlosser RJ, Hwang PH, Mace JC, Soler ZM (2014) Productivity costs in patients with refractory chronic rhinosinusitis. Laryngoscope 124:2007–2012CrossRef Rudmik L, Smith TL, Schlosser RJ, Hwang PH, Mace JC, Soler ZM (2014) Productivity costs in patients with refractory chronic rhinosinusitis. Laryngoscope 124:2007–2012CrossRef
4.
Zurück zum Zitat Phillips KM, Hoehle LP, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2017) Acute exacerbations mediate quality of life impairment in chronic rhinosinusitis. J Allergy Clin Immunol Pract 5:422–426CrossRef Phillips KM, Hoehle LP, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2017) Acute exacerbations mediate quality of life impairment in chronic rhinosinusitis. J Allergy Clin Immunol Pract 5:422–426CrossRef
5.
Zurück zum Zitat Banoub RG, Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Relationship between chronic rhinosinusitis exacerbation frequency and asthma control. Laryngoscope 128:1033–1038CrossRef Banoub RG, Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Relationship between chronic rhinosinusitis exacerbation frequency and asthma control. Laryngoscope 128:1033–1038CrossRef
6.
Zurück zum Zitat Phillips KM, Bergmark RW, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Chronic rhinosinusitis exacerbations are differentially associated with lost productivity based on asthma status. Rhinology 56:323PubMed Phillips KM, Bergmark RW, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Chronic rhinosinusitis exacerbations are differentially associated with lost productivity based on asthma status. Rhinology 56:323PubMed
7.
Zurück zum Zitat Hopkins C, Gillett S, Slack R, Lund VJ, Browne JP (2009) Psychometric validity of the 22-item Sinonasal Outcome Test. Clin Otolaryngol 34:447–454CrossRef Hopkins C, Gillett S, Slack R, Lund VJ, Browne JP (2009) Psychometric validity of the 22-item Sinonasal Outcome Test. Clin Otolaryngol 34:447–454CrossRef
8.
Zurück zum Zitat Hopkins C, Hettige R, Soni-Jaiswal A et al (2018) CHronic Rhinosinusitis Outcome MEasures (CHROME), developing a core outcome set for trials of interventions in chronic rhinosinusitis. Rhinology 56:22–32CrossRef Hopkins C, Hettige R, Soni-Jaiswal A et al (2018) CHronic Rhinosinusitis Outcome MEasures (CHROME), developing a core outcome set for trials of interventions in chronic rhinosinusitis. Rhinology 56:22–32CrossRef
9.
Zurück zum Zitat Sedaghat AR, Gray ST, Caradonna SD, Caradonna DS (2015) Clustering of chronic rhinosinusitis symptomatology reveals novel associations with objective clinical and demographic characteristics. Am J Rhinol Allergy 29:100–105CrossRef Sedaghat AR, Gray ST, Caradonna SD, Caradonna DS (2015) Clustering of chronic rhinosinusitis symptomatology reveals novel associations with objective clinical and demographic characteristics. Am J Rhinol Allergy 29:100–105CrossRef
10.
Zurück zum Zitat Hoehle LP, Phillips KM, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2016) Symptoms of chronic rhinosinusitis differentially impact general health-related quality of life. Rhinology 54:316–322CrossRef Hoehle LP, Phillips KM, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2016) Symptoms of chronic rhinosinusitis differentially impact general health-related quality of life. Rhinology 54:316–322CrossRef
11.
Zurück zum Zitat Speth MM, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) Changes in chronic rhinosinusitis symptoms differentially associate with improvement in general health-related quality of life. Ann Allergy Asthma Immunol 121:195CrossRef Speth MM, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) Changes in chronic rhinosinusitis symptoms differentially associate with improvement in general health-related quality of life. Ann Allergy Asthma Immunol 121:195CrossRef
12.
Zurück zum Zitat Campbell AP, Phillips KM, Hoehle LP et al (2017) Depression symptoms and lost productivity in chronic rhinosinusitis. Ann Allergy Asthma Immunol 118:286–289CrossRef Campbell AP, Phillips KM, Hoehle LP et al (2017) Depression symptoms and lost productivity in chronic rhinosinusitis. Ann Allergy Asthma Immunol 118:286–289CrossRef
13.
Zurück zum Zitat Wilkinson TMA, Aris E, Bourne S et al (2017) A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD. Thorax 72:919–927CrossRef Wilkinson TMA, Aris E, Bourne S et al (2017) A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD. Thorax 72:919–927CrossRef
14.
Zurück zum Zitat Kuiper JR, Hirsch AG, Bandeen-Roche K et al (2018) Prevalence, severity, and risk factors for acute exacerbations of nasal and sinus symptoms by chronic rhinosinusitis status. Allergy 73:1244–1253CrossRef Kuiper JR, Hirsch AG, Bandeen-Roche K et al (2018) Prevalence, severity, and risk factors for acute exacerbations of nasal and sinus symptoms by chronic rhinosinusitis status. Allergy 73:1244–1253CrossRef
15.
Zurück zum Zitat Denlinger LC, Sorkness RL, Lee WM et al (2011) Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation. Am J Respir Crit Care Med 184:1007–1014CrossRef Denlinger LC, Sorkness RL, Lee WM et al (2011) Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation. Am J Respir Crit Care Med 184:1007–1014CrossRef
16.
Zurück zum Zitat Kaffash-Charandabi N, Alesheikh AA, Sharif M (2019) A ubiquitous asthma monitoring framework based on ambient air pollutants and individuals' contexts. Environ Sci Pollut Res Int 26:7525–7539CrossRef Kaffash-Charandabi N, Alesheikh AA, Sharif M (2019) A ubiquitous asthma monitoring framework based on ambient air pollutants and individuals' contexts. Environ Sci Pollut Res Int 26:7525–7539CrossRef
17.
Zurück zum Zitat Banoub RG, Hoehle LP, Phillips KM et al (2018) Depressed mood modulates impact of chronic rhinosinusitis symptoms on quality of life. J Allergy Clin Immunol Pract 6:2098CrossRef Banoub RG, Hoehle LP, Phillips KM et al (2018) Depressed mood modulates impact of chronic rhinosinusitis symptoms on quality of life. J Allergy Clin Immunol Pract 6:2098CrossRef
18.
Zurück zum Zitat Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al (2015) Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 152:39 Rosenfeld RM, Piccirillo JF, Chandrasekhar SS et al (2015) Clinical practice guideline (update): adult sinusitis. Otolaryngol Head Neck Surg 152:39
19.
Zurück zum Zitat Campbell AP, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2017) Smoking: an independent risk factor for lost productivity in chronic rhinosinusitis. Laryngoscope 127:1742–1745CrossRef Campbell AP, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2017) Smoking: an independent risk factor for lost productivity in chronic rhinosinusitis. Laryngoscope 127:1742–1745CrossRef
20.
Zurück zum Zitat Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) A contemporary analysis of clinical and demographic factors of chronic rhinosinusitis patients and their association with disease severity. Ir J Med Sci 187:215–221CrossRef Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) A contemporary analysis of clinical and demographic factors of chronic rhinosinusitis patients and their association with disease severity. Ir J Med Sci 187:215–221CrossRef
21.
Zurück zum Zitat Phillips KM, Hoehle L, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2017) Reversal of smoking effects on chronic rhinosinusitis after smoking cessation. Otolaryngol Head Neck Surg 157:737–742CrossRef Phillips KM, Hoehle L, Bergmark RW, Caradonna DS, Gray ST, Sedaghat AR (2017) Reversal of smoking effects on chronic rhinosinusitis after smoking cessation. Otolaryngol Head Neck Surg 157:737–742CrossRef
22.
Zurück zum Zitat Feng AL, Wesely NC, Hoehle LP et al (2017) A validated model for the 22-item Sino-Nasal Outcome Test subdomain structure in chronic rhinosinusitis. Int Forum Allergy Rhinol 7:1140–1148CrossRef Feng AL, Wesely NC, Hoehle LP et al (2017) A validated model for the 22-item Sino-Nasal Outcome Test subdomain structure in chronic rhinosinusitis. Int Forum Allergy Rhinol 7:1140–1148CrossRef
23.
Zurück zum Zitat Team RDC (2011) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna Team RDC (2011) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna
24.
Zurück zum Zitat Kendler KS (2017) The genealogy of major depression: symptoms and signs of melancholia from 1880 to 1900. Mol Psychiatry 22:1539–1553CrossRef Kendler KS (2017) The genealogy of major depression: symptoms and signs of melancholia from 1880 to 1900. Mol Psychiatry 22:1539–1553CrossRef
25.
Zurück zum Zitat Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Minimal clinically important difference for the 22-item Sinonasal Outcome Test in medically managed patients with chronic rhinosinusitis. Clin Otolaryngol 43:1328–1334CrossRef Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2018) Minimal clinically important difference for the 22-item Sinonasal Outcome Test in medically managed patients with chronic rhinosinusitis. Clin Otolaryngol 43:1328–1334CrossRef
26.
Zurück zum Zitat Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2019) Determinants of noticeable symptom improvement despite sub-MCID change in SNOT-22 score after treatment for chronic rhinosinusitis. Int Forum Allergy Rhinol 9:508CrossRef Phillips KM, Hoehle LP, Caradonna DS, Gray ST, Sedaghat AR (2019) Determinants of noticeable symptom improvement despite sub-MCID change in SNOT-22 score after treatment for chronic rhinosinusitis. Int Forum Allergy Rhinol 9:508CrossRef
28.
Zurück zum Zitat Wu TJ, Pan SC, Chen BY, Chin WS, Guo YL (2018) Different seasonal effect on asthma trajectories: a population-based birth cohort study. Pediatr Allergy Immunol 29:873–877CrossRef Wu TJ, Pan SC, Chen BY, Chin WS, Guo YL (2018) Different seasonal effect on asthma trajectories: a population-based birth cohort study. Pediatr Allergy Immunol 29:873–877CrossRef
29.
Zurück zum Zitat Shrestha P, Poudel DR, Dhital R, Karmacharya P (2018) Seasonal and regional variation of asthma-related hospitalizations and mortality among adults in the United States. Ann Allergy Asthma Immunol 121:368–369CrossRef Shrestha P, Poudel DR, Dhital R, Karmacharya P (2018) Seasonal and regional variation of asthma-related hospitalizations and mortality among adults in the United States. Ann Allergy Asthma Immunol 121:368–369CrossRef
30.
Zurück zum Zitat Witonsky J, Abraham R, Toh J et al (2018) The association of environmental, meteorological, and pollen count variables with asthma-related emergency department visits and hospitalizations in the Bronx. J Asthma 12:1–11 Witonsky J, Abraham R, Toh J et al (2018) The association of environmental, meteorological, and pollen count variables with asthma-related emergency department visits and hospitalizations in the Bronx. J Asthma 12:1–11
31.
Zurück zum Zitat Rank MA, Wollan P, Kita H, Yawn BP (2010) Acute exacerbations of chronic rhinosinusitis occur in a distinct seasonal pattern. J Allergy Clin Immunol 126:168–169CrossRef Rank MA, Wollan P, Kita H, Yawn BP (2010) Acute exacerbations of chronic rhinosinusitis occur in a distinct seasonal pattern. J Allergy Clin Immunol 126:168–169CrossRef
32.
Zurück zum Zitat Lima JT, Paula FE, Proenca-Modena JL et al (2015) The seasonality of respiratory viruses in patients with chronic rhinosinusitis. Am J Rhinol Allergy 29:19–22CrossRef Lima JT, Paula FE, Proenca-Modena JL et al (2015) The seasonality of respiratory viruses in patients with chronic rhinosinusitis. Am J Rhinol Allergy 29:19–22CrossRef
33.
Zurück zum Zitat Tan KS, Yan Y, Ong HH, Chow VTK, Shi L, Wang DY (2017) Impact of respiratory virus infections in exacerbation of acute and chronic rhinosinusitis. Curr Allergy Asthma Rep 17:24CrossRef Tan KS, Yan Y, Ong HH, Chow VTK, Shi L, Wang DY (2017) Impact of respiratory virus infections in exacerbation of acute and chronic rhinosinusitis. Curr Allergy Asthma Rep 17:24CrossRef
34.
Zurück zum Zitat Marcus S, Roland LT, DelGaudio JM, Wise SK (2019) The relationship between allergy and chronic rhinosinusitis. Laryngoscope Investig Otolaryngol 4:13CrossRef Marcus S, Roland LT, DelGaudio JM, Wise SK (2019) The relationship between allergy and chronic rhinosinusitis. Laryngoscope Investig Otolaryngol 4:13CrossRef
35.
Zurück zum Zitat Kurlansik SL, Ibay AD (2012) Seasonal affective disorder. Am Fam Physician 86:1037–1041PubMed Kurlansik SL, Ibay AD (2012) Seasonal affective disorder. Am Fam Physician 86:1037–1041PubMed
36.
Zurück zum Zitat Erskine SE, Hopkins C, Clark A et al (2017) Chronic rhinosinusitis and mood disturbance. Rhinology 55:113–119CrossRef Erskine SE, Hopkins C, Clark A et al (2017) Chronic rhinosinusitis and mood disturbance. Rhinology 55:113–119CrossRef
37.
Zurück zum Zitat Campbell AP, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) Depressed mood is associated with loss of productivity in allergic rhinitis. Allergy 73:1141–1144CrossRef Campbell AP, Hoehle LP, Phillips KM, Caradonna DS, Gray ST, Sedaghat AR (2018) Depressed mood is associated with loss of productivity in allergic rhinitis. Allergy 73:1141–1144CrossRef
38.
Zurück zum Zitat Axelsson J, Stefansson JG, Magnusson A, Sigvaldason H, Karlsson MM (2002) Seasonal affective disorders: relevance of Icelandic and Icelandic–Canadian evidence to etiologic hypotheses. Can J Psychiatry 47:153–158CrossRef Axelsson J, Stefansson JG, Magnusson A, Sigvaldason H, Karlsson MM (2002) Seasonal affective disorders: relevance of Icelandic and Icelandic–Canadian evidence to etiologic hypotheses. Can J Psychiatry 47:153–158CrossRef
39.
Zurück zum Zitat Brancaleoni G, Nikitenkova E, Grassi L, Hansen V (2009) Seasonal affective disorder and latitude of living. Epidemiol Psychiatr Soc 18:336–343CrossRef Brancaleoni G, Nikitenkova E, Grassi L, Hansen V (2009) Seasonal affective disorder and latitude of living. Epidemiol Psychiatr Soc 18:336–343CrossRef
40.
Zurück zum Zitat Grimaldi S, Partonen T, Haukka J, Aromaa A, Lonnqvist J (2009) Seasonal vegetative and affective symptoms in the Finnish general population: testing the dual vulnerability and latitude effect hypotheses. Nord J Psychiatry 63:397–404CrossRef Grimaldi S, Partonen T, Haukka J, Aromaa A, Lonnqvist J (2009) Seasonal vegetative and affective symptoms in the Finnish general population: testing the dual vulnerability and latitude effect hypotheses. Nord J Psychiatry 63:397–404CrossRef
41.
Zurück zum Zitat Imai M, Kayukawa Y, Ohta T, Li L, Nakagawa T (2003) Cross-regional survey of seasonal affective disorders in adults and high-school students in Japan. J Affect Disord 77:127–133CrossRef Imai M, Kayukawa Y, Ohta T, Li L, Nakagawa T (2003) Cross-regional survey of seasonal affective disorders in adults and high-school students in Japan. J Affect Disord 77:127–133CrossRef
42.
Zurück zum Zitat Kegel M, Dam H, Ali F, Bjerregaard P (2009) The prevalence of seasonal affective disorder (SAD) in Greenland is related to latitude. Nord J Psychiatry 63:331–335CrossRef Kegel M, Dam H, Ali F, Bjerregaard P (2009) The prevalence of seasonal affective disorder (SAD) in Greenland is related to latitude. Nord J Psychiatry 63:331–335CrossRef
Metadaten
Titel
Seasonal variations in chronic rhinosinusitis symptom burden may be explained by changes in mood
verfasst von
Rehab Talat
Katie M. Phillips
David S. Caradonna
Stacey T. Gray
Ahmad R. Sedaghat
Publikationsdatum
15.07.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 10/2019
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05555-w

Weitere Artikel der Ausgabe 10/2019

European Archives of Oto-Rhino-Laryngology 10/2019 Zur Ausgabe

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.