The online version of this article (doi:10.1186/1752-1947-8-405) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
HY participated in the design of the study. HY, SY, EY and BC performed patient management. SB performed the embolization. HY drafted the manuscript, conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.
The technique of selective embolization has been applied for years in the treatment of vascular anomalies, severe hemorrhage, and for benign and malignant tumors. Some hypervascular skeletal metastases are prone to massive hemorrhage.
We describe the cases of two patients with thyroid carcinoma presenting with neuromuscular symptoms due to large skeletal metastases in the shoulder and sternum respectively. Pre-operative percutaneous selective catheterizations of the arteries feeding the metastatic tumors were performed, followed by infusion of gelfoam. The procedures were technically successful in both patients without adverse effects or bleeding. Complete resections of the skeletal metastases were then performed without substantial bleeding.
Selective embolization is an effective treatment for bony metastases from thyroid cancer.
Authors’ original file for figure 113256_2014_3008_MOESM1_ESM.tif
Authors’ original file for figure 213256_2014_3008_MOESM2_ESM.tif
Authors’ original file for figure 313256_2014_3008_MOESM3_ESM.jpeg
Authors’ original file for figure 413256_2014_3008_MOESM4_ESM.jpeg
Authors’ original file for figure 513256_2014_3008_MOESM5_ESM.jpeg
Authors’ original file for figure 613256_2014_3008_MOESM6_ESM.jpeg
Authors’ original file for figure 713256_2014_3008_MOESM7_ESM.jpeg
Authors’ original file for figure 813256_2014_3008_MOESM8_ESM.jpeg
Smit JW, Links TP, Hew JM, Goslings BM, Vielvoye GJ, Vermey A: Embolization of skeletal metastases in patients with differentiated thyroid carcinoma. Ned Tijdschr Geneeskd. 2000, 144 (29): 1406-1410. PubMed
Kim TH, Jung JH, Tae K, Chung WS: A case of follicular thyroid carcinoma with metastasis to the sternum. Korean J Otorhinolaryngol-Head Neck Surg. 2010, 53: 390-393. 10.3342/kjorl-hns.2010.53.6.390. CrossRef
Schmitt TS, Elte JW, Rietveld AP, van Zaanen HC, Castro CM: Bone metastasis of a follicular thyroid carcinoma originated in a toxic multinodular goiter. Eur J Intern Med. 2008, 19 (7): 64-66. 10.1016/j.ejim.2008.03.014. CrossRef
Zettinig G, Fueger BJ, Passler C, Kaserer K, Pirich C, Dudczak R, Niederle B: Long-term follow-up of patients with bone metastases from differentiated thyroid carcinoma – surgery or conventional therapy?. Clin Endocrinol. 2002, 56 (3): 377-382. 10.1046/j.1365-2265.2002.01482.x. CrossRef
Emmanouilides C, Chourmouzi D, Dedes I, Pantoleon D, Mantziari P, Drevelengas A: Successful management of bulky osseous metastasis of renal cell carcinoma with selective arterial embolization and radiofrequency ablation: a case report. Cases J. 2009, 2: 6484-10.4076/1757-1626-2-6484. CrossRefPubMedPubMedCentral
Meyer A, Behrend M: Partial resection of the sternum for osseous metastasis of differentiated thyroid cancer: case report. Anticancer Res. 2005, 25 (6C): 4389-4392. PubMed
- Selective embolization for hypervascular metastasis from differentiated thyroid cancer: a case series
Hee Young Son
Eui Young Kim
Sang Bu Ahn
Byung Chul Lee
- BioMed Central