Erschienen in:
08.09.2022 | Original Article
Selective local postoperative radiotherapy for T3–T4 N0 laryngeal cancer
verfasst von:
Dr. Meltem Dağdelen, Merve Şahin, Tuba Kurt Çatal, Halil Cumhur Yıldırım, Songül Çavdar Karaçam, Kimia Çepni, Ömer Erol Uzel
Erschienen in:
Strahlentherapie und Onkologie
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Ausgabe 11/2022
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Abstract
Purpose
We aimed to investigate the appropriate postoperative radiotherapy dose and selective volume in T3–4 N0 laryngeal cancer patients treated with either total or partial laryngectomy.
Methods
Patients who received radiotherapy for locally advanced (T3–T4) and pathologic node-negative (N0) squamous cell laryngeal cancer were retrospectively evaluated. Radiotherapy was applied to median 60 Gy (range 54–60 Gy) as selective local radiotherapy (±stoma). The local treatment areas included postoperative bed + laryngeal area for patients with a partial laryngectomy, and the postoperative bed only for patients with total laryngectomy.
Results
The median follow-up time was 59 months and 52 patients were included. The 2‑year, 5‑year, and 8‑year locoregional recurrence controls (LRC) were 95.6%. The 2‑year and 5‑year OS rates were 93.8% and 78.9%, respectively. The 5‑year OS for age < 60 years was 95.8%, for above 60 years 56.5%.
Conclusion
Our data suggest that local selective irradiation to the postoperative bed + stoma is enough in patients with T3–4 N0 laryngeal cancer without applying elective nodal irradiation.