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Erschienen in: Documenta Ophthalmologica 2/2013

01.04.2013 | Original Research Article

Sensitivity and specificity of the step VEP in suspected functional visual acuity loss

verfasst von: Ruth Hamilton, Michael S. Bradnam, Gordon N. Dutton, Anna L. Lai Chooi Yan, Tim E. Lavy, I. Livingstone, Alison M. Mackay, Jane R. Mackinnon

Erschienen in: Documenta Ophthalmologica | Ausgabe 2/2013

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Abstract

Background/aim

Early and accurate diagnosis of functional visual loss (FVL) allows optimum management. Visual evoked potentials (VEPs) offer a means of objectively estimating acuity and therefore could assist with early and accurate diagnosis. The aim of this study was to assess the sensitivity and specificity of the step VEP in diagnosing FVL.

Methods

A retrospective audit was conducted in 36 school-aged children presenting with reduced visual acuity and clinical suspicion of FVL. All had undergone step VEP testing as part of their investigation. Medical notes were reviewed, and where necessary, referring centres, general practitioners or electronic clinical portals were consulted to obtain longer-term outcome data.

Results

Twenty-seven of the 36 patients (75 %) were classified as having had FVL: all had a normal step VEP spatial threshold. Nine patients (25 %) had an organic cause for their acuity loss, of whom seven had abnormal step VEP spatial thresholds: the other two patients had some functional overlay to their organic disease. The step VEP sensitivity was 78 % (95 % confidence interval 40–96 %), and specificity was 100 % (95 % confidence interval 84–100 %).

Conclusion

The high specificity of the step VEP for FVL warrants increased suspicion of an organic cause should the step VEP spatial threshold be abnormal.
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Metadaten
Titel
Sensitivity and specificity of the step VEP in suspected functional visual acuity loss
verfasst von
Ruth Hamilton
Michael S. Bradnam
Gordon N. Dutton
Anna L. Lai Chooi Yan
Tim E. Lavy
I. Livingstone
Alison M. Mackay
Jane R. Mackinnon
Publikationsdatum
01.04.2013
Verlag
Springer-Verlag
Erschienen in
Documenta Ophthalmologica / Ausgabe 2/2013
Print ISSN: 0012-4486
Elektronische ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-012-9362-x

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