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Erschienen in: Endocrine 2/2018

02.07.2018 | Endocrine Surgery

Sentinel lymph node biopsy in small papillary thyroid cancer. A review on novel surgical techniques

verfasst von: Ludovico Maria Garau, Domenico Rubello, Alice Ferretti, Giuseppe Boni, Duccio Volterrani, Gianpiero Manca

Erschienen in: Endocrine | Ausgabe 2/2018

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Abstract

Purpose

Sentinel lymph node biopsy (SNB) in patients with papillary thyroid carcinoma (PTC) and negative for clinically neck lymph node metastatic involvement (N0) has emerged as a promising minimally invasive procedure to detect metastatic nodes.

Methods

The MEDLINE database was searched via the PubMed interface on 10 January 2018 for the MeSH headings “sentinel lymph node biopsy” and “thyroid carcinoma”.

Results

Vital blue dye, radioisotope, and the combination of both techniques are used in PTC patients. These methods and the emerging role of SPECT/CT are discussed in this review. The sentinel lymph node (SLN) identification rates ranged from 0 to 100% for blue dye, 83 to 100% for radioisotopes, and 66 to 100% for the combination of both techniques, respectively.

Conclusions

SNB based on radioisotope technique with the use of intraoperative gamma-probe is an accurate and safe method that allows the highest SLN detection rate. There is sufficient evidence to propagate the increasing use of SNB procedure that has the potential to avoid prophylactic lymph node surgery in patients clinically N0.
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Metadaten
Titel
Sentinel lymph node biopsy in small papillary thyroid cancer. A review on novel surgical techniques
verfasst von
Ludovico Maria Garau
Domenico Rubello
Alice Ferretti
Giuseppe Boni
Duccio Volterrani
Gianpiero Manca
Publikationsdatum
02.07.2018
Verlag
Springer US
Erschienen in
Endocrine / Ausgabe 2/2018
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-018-1658-5

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