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01.03.2012 | Original Paper | Ausgabe 3/2012

International Orthopaedics 3/2012

Serum metal ion levels after rotating-hinge knee arthroplasty: comparison between a standard device and a megaprosthesis

Zeitschrift:
International Orthopaedics > Ausgabe 3/2012
Autoren:
Joerg Friesenbichler, Werner Maurer-Ertl, Patrick Sadoghi, Thomas Lovse, Reinhard Windhager, Andreas Leithner
Wichtige Hinweise
The study was approved by the Ethics Committee, and informed consent was obtained from all patients.

Abstract

Purpose

The effects of systemic metal ion exposure in patients with implants made of common prosthetic alloys continue to be a matter of concern. The aim of the study was to determine the measurement values of cobalt (Co), chromium (Cr) and molybdenum (Mo) in serum following rotating-hinge knee arthroplasty.

Methods

Blood was taken from 25 patients [mean follow-up 35 (range nine to 67) months] treated with megaprostheses (n=17) or standard rotating-hinge devices (n=8) and analysed using electrothermal graphite furnace atomic absorption spectrometry (ET-ASS).

Results

Determining the concentrations of metal ions following rotating-hinge knee arthroplasty revealed increments for Co and Cr but not Mo. Metal ion release was significantly higher in patients with megaprostheses compared to a standard rotating-hinge knee device (Co p=0,024; Cr p=0.025).

Conclusion

The authors believe there might be an additional metal ion release from the surface of the prosthesis and not only from the articulating surfaces because, in cases of rotating-hinge knee prosthesis, there is a metal-on-polyethylene articulation and not a direct metal-on-metal junction. Nevertheless, long-term studies are required to determine adverse effects of Co, Cr and Mo following total hip replacement and total knee arthroplasty.

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