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10.02.2016 | Original Article

Setup accuracy for prone and supine whole breast irradiation

verfasst von: Thomas Mulliez, M.D., Ph.D., Akos Gulyban, MSc., Ph.D., Tom Vercauteren, MSc., Annick van Greveling, RN, Bruno Speleers, RTT, Wilfried De Neve, M.D., Ph.D., Liv Veldeman, M.D., Ph.D.

Erschienen in: Strahlentherapie und Onkologie | Ausgabe 4/2016

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Abstract

Purpose

To evaluate cone-beam computed tomography (CBCT) based setup accuracy and margins for prone and supine whole breast irradiation (WBI).

Methods

Setup accuracy was evaluated on 3559 CBCT scans of 242 patients treated with WBI and uncertainty margins were calculated using the van Herk formula. Uni- and multivariate analysis on individual margins was performed for age, body mass index (BMI) and cup size.

Results

The population-based margin in vertical (VE), lateral (LA) and longitudinal (LO) directions was 10.4/9.4/9.4 mm for the 103 supine and 10.5/22.4/13.7 mm for the 139 prone treated patients, being significantly (p < 0.01) different for the LA and LO directions. Multivariate analysis identified a significant (p < 0.05) correlation between BMI and the LO margin in supine position and the VE/LA margin in prone position.

Conclusion

In this series, setup accuracy is significantly worse in prone compared to supine position for the LA and LO directions. However, without proper image-guidance, uncertainty margins of about 1 cm are also necessary for supine WBI. For patients with a higher BMI, larger margins are required.

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Titel: Setup accuracy for prone and supine whole breast irradiation
verfasst von: Thomas Mulliez, M.D., Ph.D.
Akos Gulyban, MSc., Ph.D.
Tom Vercauteren, MSc.
Annick van Greveling, RN
Bruno Speleers, RTT
Wilfried De Neve, M.D., Ph.D.
Liv Veldeman, M.D., Ph.D.
Publikationsdatum: 10.02.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Strahlentherapie und Onkologie / Ausgabe 4/2016
Print ISSN: 0179-7158
Elektronische ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-016-0943-6

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Setup accuracy for prone and supine whole breast irradiation

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