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01.12.2017 | Research article | Ausgabe 1/2017 Open Access

BMC Musculoskeletal Disorders 1/2017

Sex differences in gout characteristics: tailoring care for women and men

Zeitschrift:
BMC Musculoskeletal Disorders > Ausgabe 1/2017
Autoren:
Leslie R. Harrold, Carol J. Etzel, Allan Gibofsky, Joel M. Kremer, Michael H. Pillinger, Kenneth G. Saag, Naomi Schlesinger, Robert Terkeltaub, Vanessa Cox, Jeffrey D. Greenberg
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12891-017-1465-9) contains supplementary material, which is available to authorized users.

Abstract

Background

To characterize the differences between women and men with gout.

Methods

We analyzed a US national cohort of gout patients cared for by rheumatologists.

Results

Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).

Conclusions

The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
Zusatzmaterial
Additional file 1: Table S1. Baseline characteristics. (DOCX 15 kb)
12891_2017_1465_MOESM1_ESM.docx
Additional file 2: Table S2. Dosing of urate-lowering therapies among eligible patients. (DOCX 12 kb)
12891_2017_1465_MOESM2_ESM.docx
Additional file 3: Figure S1. Comparison of the dietary servings among women and men with gout. The p values represent adjusted analyses adjusting for age, BMI, duration of gout, comorbidity burden [hypertension, diabetes, renal disease, hyperlipidemia], HCTZ use, other diuretic use and current use of a urate-lowering drug. (TIF 320 kb)
12891_2017_1465_MOESM3_ESM.tif
Literatur
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