Skip to main content
Erschienen in: Diabetologia 12/2017

13.09.2017 | Letter

SGLT2 inhibitors and cancer: why further evidence is required

verfasst von: Altamash M. Y. Shaikh

Erschienen in: Diabetologia | Ausgabe 12/2017

Einloggen, um Zugang zu erhalten

Excerpt

To the Editor: The article on sodium–glucose cotransporter 2 (SGLT2) inhibitors and cancers by Tang et al [1], which was recently published in Diabetologia, is very relevant to practice in today’s world. However, this letter is to bring to your kind attention an error in this article. Tang and colleagues conducted a meta-analysis of RCTs to identify any risk of cancer with SGLT2 inhibitors. The results suggested a possible increased risk of bladder cancer with empagliflozin therapy. We noted a possible error in the paper, as discussed below. …
Literatur
2.
Zurück zum Zitat Zinman B, Wanner C, Lachin JM (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. NEJM 373:2117–2128CrossRefPubMed Zinman B, Wanner C, Lachin JM (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. NEJM 373:2117–2128CrossRefPubMed
4.
Zurück zum Zitat Scafoglio C, Hirayama BA, Kepe V et al (2015) Functional expression of sodium-glucose transporters in cancer. Proc Natl Acad Sci U S A 112:E4111–E4119CrossRefPubMedPubMedCentral Scafoglio C, Hirayama BA, Kepe V et al (2015) Functional expression of sodium-glucose transporters in cancer. Proc Natl Acad Sci U S A 112:E4111–E4119CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Ptaszynska A, Cohen SM, Messing EM, Reilly TP, Johnsson E, Johnsson K (2015) Assessing bladder cancer risk in type 2 diabetes clinical trials: the dapagliflozin drug development program as a ‘case study’. Diabetes Ther 6:357–375CrossRefPubMedPubMedCentral Ptaszynska A, Cohen SM, Messing EM, Reilly TP, Johnsson E, Johnsson K (2015) Assessing bladder cancer risk in type 2 diabetes clinical trials: the dapagliflozin drug development program as a ‘case study’. Diabetes Ther 6:357–375CrossRefPubMedPubMedCentral
Metadaten
Titel
SGLT2 inhibitors and cancer: why further evidence is required
verfasst von
Altamash M. Y. Shaikh
Publikationsdatum
13.09.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Diabetologia / Ausgabe 12/2017
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-017-4434-9

Weitere Artikel der Ausgabe 12/2017

Diabetologia 12/2017 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.