Anzeige
Erschienen in:
04.01.2018 | Original Article
Sham Feeding with Bacon Does Not Alter Transit Time or Complete Examination Rate During Small Bowel Capsule Endoscopy
Erschienen in: Digestive Diseases and Sciences | Ausgabe 2/2018
Einloggen, um Zugang zu erhaltenAbstract
Background
During capsule endoscopy (CE) studies, the complete examination rate (CER) can be increased by prolonging capsule battery life or reducing gastric transit time (GTT) and/or small bowel transit time (SBTT). However, despite enhanced battery life, 10% of studies remain incomplete. Previously studied interventions to reduce SBTT and enhance CER have produced conflicting results. We hypothesize that this may be a consequence of an insufficiently potent stimulus of small bowel motility.
Aims
To examine whether potent stimulation of the cephalic response of digestion during small bowel CE reduces GTT and/or SBTT and thus increases the CER.
Methods
A single-blind randomized trial was performed to evaluate the effect of bacon sham feeding on GTT, SBTT and CER.
Results
Baseline characteristics were similar between 63 sham fed patients and 59 controls. The median GTT was 17 min (9–65) in the bacon group and 25 min (14–55) in the control group. The median SBTT was 199 min (119–316) and 222 min (151–287), respectively. Cox proportional hazards model demonstrated no significant difference between groups for GTT (rate ratio 1.03, 95% CI 0.71–1.51, P = 0.87) or SBTT (rate ratio 1.02, 95% CI 0.70–1.49, P = 0.93). Although the taste of bacon was considered favorably by 72% of participants, taste did not correlate with GTT (ρ = 0.03, P = 0.83) or SBTT (ρ = − 0.115, P = 0.33). The CER was 91 and 95% in the bacon and control groups, respectively (P = 0.35).
Conclusion
Bacon sham feeding has no effect on GTT, SBTT or CER and cannot be recommended in clinical practice.