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01.12.2014 | Commentary | Ausgabe 1/2014 Open Access

Respiratory Research 1/2014

Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis

Zeitschrift:
Respiratory Research > Ausgabe 1/2014
Autoren:
Tavs Qvist, Tania Pressler, Niels Høiby, Terese L Katzenstein
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

Manuscript was drafted by TQ and TLK. Concept was developed in collaboration with TP and NH who assisted in revision of the manuscript. All authors have seen and approved the finished manuscript. The manuscript has not previously been published nor is it being considered for publication elsewhere.

Abstract

Important paradigms of pulmonary disease with nontuberculous mycobacteria (NTM) are currently shifting based on an increasing attention within the field of cystic fibrosis (CF). These shifts are likely to benefit the management of all patients with pulmonary NTM, regardless of underlying pathology. Currently several key areas are being revised: The first outbreak of human NTM transmission has been proven and new evidence of biofilm growth in vivo has been demonstrated. A better understanding of the clinical impact of NTM infection has led to increased diagnostic vigilance and new recommendations for lung transplantation are under way. While recent changes have reinvigorated the interest in NTM disease, the challenge remains, whether such advances can be successfully translated into improved management and care.
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