Electronic supplementary material
Hemangioma-derived endothelial cell
CD31/PECAM-1, vWF, E-selectin, VEGFR-2, Tie-2 and VE-cadherin
Immature endothelial cells; Clonal expansion; Increased proliferation, migration, tumor formation and survival ability.
Hemangioma-derived endothelial progenitor cell
CD133*, VEGFR-2, CD34, CD31, CD146, VE-cadherin and vWF
Immature endothelial cells; Increased adhesion, migration and proliferation in the presence of endostatin or VEGF.
Hemangioma-derived mesenchymal stem cell
SH2(CD105), SH3, SH4, CD90, CD29, α-SMA and CD133
Multilineage differentiation: adipogenic, osteoblastic and myoblastic differentiation
Hemangioma-derived stem cell
CD90, CD133, VEGFR-1, VEGFR-2, neuroplin-1 and CD146
Multilineage differentiation: ECs, neuronal cells, adipocytes, osteocytes and chondrocytes; Form hemangioma-like Glut-1+ blood vessels in nude mice.
PDGFR-β, neural glial antigen-2, desmin, calponin, smooth muscle 22α, smooth muscle α-actin, α-SMA, smooth muscle myosin heavy chain and CD90
Increased proliferation ability; Reduced contractility; Diminished ability to stabilize blood vessels in IH.