Significance of Adopting a Sensitive Technique for Donor Antibody Screening

Excerpt

Immunohematology is an integral part of transfusion medicine. In the past few decades, significant efforts have been made to detect as many irregular antibodies as possible in both transfusion recipients, pregnant mothers and blood donors. Traditionally antibody screening was performed with conventional tube technique (CTT), which was considered the gold standard. With advances in hemagglutination techniques like column agglutination technique (CAT), antibody screening in blood donors has become easier. Antibody screening in blood donors is done to avoid adverse transfusion reactions in recipients of plasma transfusion like immune hemolysis which can occur in patients for whom large amount of plasma is transfused or in pediatric patients [1]. …