Anzeige
Erschienen in:
14.06.2018 | Original Article
Simple quantification of paracardial and epicardial fat dimensions at low-dose chest CT: correlation with metabolic risk factors and usefulness in predicting metabolic syndrome
Erschienen in: Japanese Journal of Radiology | Ausgabe 9/2018
Einloggen, um Zugang zu erhaltenAbstract
Purpose
To assess the usefulness of simple axial bi-dimensional diameters of pericardial fat tissues at low-dose chest CT, in correlation with metabolic parameters in predicting metabolic syndrome.
Materials and methods
Subjects were 373 asymptomatic individuals who performed both low-dose chest CT and abdominal fat CT for medical check-up. Maximum bi-dimensional axial diameters of paracardial fats at right (RPF) and left (LPF) cardiophrenic angle portions, and epicardial fats around right (REF) and left (LEF) coronary arteries, and coronary sinus (SEF) were measured. Correlation between pericardial fat diameters and metabolic parameters were statistically analyzed.
Results
RPF, LPF, REF, LEF, and SEF diameters were moderately correlated with abdominal visceral fat (AVF) area (R = 0.74, 0.70, 0.48, 0.41, and 0.53, respectively, p < 0.01) in Pearson’s correlation analysis. In multiple linear regression analysis, coefficient of RPF for AVF showed highest value. Means of each PF and EF diameters in subjects with metabolic syndrome were significantly larger than those without metabolic syndrome (p < 0.001). All PF and EF diameters were well-discriminated for prediction of metabolic syndrome in ROC analysis (AUC values, from 0.696 to 0.795).
Conclusion
RPF diameter at low-dose chest CT would be a simple method for prediction of metabolic syndrome.