Skip to main content
Erschienen in: MMW - Fortschritte der Medizin 14/2014

21.08.2014 | FORTBILDUNG_ÜBERSICHT

Sind Sie sich dieser Gefahr bewusst?

Die periphere arterielle Verschlusskrankheit

verfasst von: Prof. Dr. med. E. Sebastian Debus, Prof. Dr. med. Giovanni Torsello, Prof. Dr. med. Thomas Hupp, Prof. Dr. med. Martin Storck, Prof. Dr. med. Werner Lang, Prof. Dr. med. Reinhart T. Grundmann

Erschienen in: MMW - Fortschritte der Medizin | Ausgabe 14/2014

Einloggen, um Zugang zu erhalten

Zusammenfassung

Der Krankheitswert der peripheren arteriellen Verschlusskrankheit wird immer noch unterschätzt. Selbst bei asymptomatischen Patienten sind die Morbidität und Mortalität deutlich erhöht. Dabei könnte man Betroffene leicht erkennen und gut behandeln. Lesen Sie hier, wie Sie das kardiovaskuläre Risiko Ihrer Patienten nachhaltig senken können.
Literatur
1.
Zurück zum Zitat Statistisches Bundesamt (Hrsg.): Gesundheitsbericht für Deutschland. Stuttgart: Metzler-Poeschel 1998 Statistisches Bundesamt (Hrsg.): Gesundheitsbericht für Deutschland. Stuttgart: Metzler-Poeschel 1998
2.
Zurück zum Zitat Rümenapf G, Diehm C. Periphere arterielle Verschlusskrankheit. Krankheitswert wird unterschätzt. Dtsch Arztebl 2011;108(40): A 2094 Rümenapf G, Diehm C. Periphere arterielle Verschlusskrankheit. Krankheitswert wird unterschätzt. Dtsch Arztebl 2011;108(40): A 2094
3.
Zurück zum Zitat Norgren L, Hiatt WR, Dormandy JA et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Eur J Vasc Endovasc Surg 2007;33 (Suppl 1):S1–75CrossRef Norgren L, Hiatt WR, Dormandy JA et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Eur J Vasc Endovasc Surg 2007;33 (Suppl 1):S1–75CrossRef
4.
Zurück zum Zitat Sigvant B, Wiberg-Hedman K, Bergqvist D et al. A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischemia and sex differences. J Vasc Surg 2007;45:1185–1191PubMedCrossRef Sigvant B, Wiberg-Hedman K, Bergqvist D et al. A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischemia and sex differences. J Vasc Surg 2007;45:1185–1191PubMedCrossRef
5.
Zurück zum Zitat Diehm C, Schuster A, Allenberg JR et al. High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study. Atherosclerosis 2004;172:95–105PubMedCrossRef Diehm C, Schuster A, Allenberg JR et al. High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study. Atherosclerosis 2004;172:95–105PubMedCrossRef
6.
Zurück zum Zitat Fowkes FG, Rudan D, Rudan I et al. Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis. Lancet 2013;382 (9901):1329–1340PubMedCrossRef Fowkes FG, Rudan D, Rudan I et al. Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis. Lancet 2013;382 (9901):1329–1340PubMedCrossRef
7.
Zurück zum Zitat Malyar N, Fürstenberg T, Wellmann J et al. Recent trends in morbidity and in-hospital outcomes of in-patients with peripheral arterial disease: a nationwide populationbased analysis. Eur Heart J 2013;34: 2706–2714PubMedCrossRef Malyar N, Fürstenberg T, Wellmann J et al. Recent trends in morbidity and in-hospital outcomes of in-patients with peripheral arterial disease: a nationwide populationbased analysis. Eur Heart J 2013;34: 2706–2714PubMedCrossRef
8.
Zurück zum Zitat Hirsch AT, Hartman L, Town RJ, Virnig BA. National health care costs of peripheral arterial disease in the Medicare population. Vasc Med 2008;13:209–515PubMedCrossRef Hirsch AT, Hartman L, Town RJ, Virnig BA. National health care costs of peripheral arterial disease in the Medicare population. Vasc Med 2008;13:209–515PubMedCrossRef
9.
Zurück zum Zitat Meves SH, Diehm C, Berger K et al. Peripheral arterial disease as an independent predictor for excess stroke morbidity and mortality in primary-care patients: 5-year results of the getABI study. Cerebrovasc Dis 2010;29:546–554PubMedCrossRef Meves SH, Diehm C, Berger K et al. Peripheral arterial disease as an independent predictor for excess stroke morbidity and mortality in primary-care patients: 5-year results of the getABI study. Cerebrovasc Dis 2010;29:546–554PubMedCrossRef
10.
Zurück zum Zitat Diehm C, Lange S, Darius H et al. Association of low ankle brachial index with high mortality in primary care. Eur Heart J 2006;27:1743–1749PubMedCrossRef Diehm C, Lange S, Darius H et al. Association of low ankle brachial index with high mortality in primary care. Eur Heart J 2006;27:1743–1749PubMedCrossRef
11.
Zurück zum Zitat Sprengers RW, Janssen KJ, Moll FL et al. Prediction rule for cardiovascular events and mortality in peripheral arterial disease patients: data from the prospective Second Manifestations of ARTerial disease (SMART) cohort study. J Vasc Surg 2009;50:1369–1376PubMedCrossRef Sprengers RW, Janssen KJ, Moll FL et al. Prediction rule for cardiovascular events and mortality in peripheral arterial disease patients: data from the prospective Second Manifestations of ARTerial disease (SMART) cohort study. J Vasc Surg 2009;50:1369–1376PubMedCrossRef
12.
Zurück zum Zitat Ankle Brachial Index Collaboration, Fowkes FG, Murray GD, Butcher I et al. Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. JAMA 2008;300:197–208PubMedCrossRef Ankle Brachial Index Collaboration, Fowkes FG, Murray GD, Butcher I et al. Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. JAMA 2008;300:197–208PubMedCrossRef
13.
Zurück zum Zitat Leeper NJ, Myers J, Zhou M et al. Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease. J Vasc Surg 2013;57:728–733PubMedCentralPubMedCrossRef Leeper NJ, Myers J, Zhou M et al. Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease. J Vasc Surg 2013;57:728–733PubMedCentralPubMedCrossRef
14.
Zurück zum Zitat Chen Q, Smith CY, Bailey KR, Wennberg PW, Kullo IJ. Disease location is associated with survival in patients with peripheral arterial disease. J Am Heart Assoc 2013;2(5):e000304CrossRef Chen Q, Smith CY, Bailey KR, Wennberg PW, Kullo IJ. Disease location is associated with survival in patients with peripheral arterial disease. J Am Heart Assoc 2013;2(5):e000304CrossRef
15.
Zurück zum Zitat Jones WS, Patel MR, Dai D et al. High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease. Am Heart J 2013;165:809–815PubMedCrossRef Jones WS, Patel MR, Dai D et al. High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease. Am Heart J 2013;165:809–815PubMedCrossRef
16.
Zurück zum Zitat Diehm C, Darius H, Pittrow D, Allenberg JR. Knöchel-Arm-Index. Ein wegweisender Risikomarker für die hausärztliche Praxis. Dtsch Arztebl 2005;102:A2310–2313 [Heft 34–35] Diehm C, Darius H, Pittrow D, Allenberg JR. Knöchel-Arm-Index. Ein wegweisender Risikomarker für die hausärztliche Praxis. Dtsch Arztebl 2005;102:A2310–2313 [Heft 34–35]
17.
Zurück zum Zitat Deutsche Gesellschaft für Angiologie. Gesellschaft für Gefäßmedizin. Leitlinien zur Diagnostik und Therapie der peripheren arteriellen Verschlusskrankheit (PAVK). AWMF-Register Nr. 065/003. Stand 27. April 2009 Deutsche Gesellschaft für Angiologie. Gesellschaft für Gefäßmedizin. Leitlinien zur Diagnostik und Therapie der peripheren arteriellen Verschlusskrankheit (PAVK). AWMF-Register Nr. 065/003. Stand 27. April 2009
18.
Zurück zum Zitat Aboyans V, Criqui MH, Abraham P et al. Measurement and interpretation of the anklebrachial index: a scientific statement from the American Heart Association. Circulation 2012;126:2890–2909PubMedCrossRef Aboyans V, Criqui MH, Abraham P et al. Measurement and interpretation of the anklebrachial index: a scientific statement from the American Heart Association. Circulation 2012;126:2890–2909PubMedCrossRef
19.
Zurück zum Zitat Rooke TW, Hirsch AT, Misra S et al. 2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral artery disease (updating the 2005 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society for Vascular Medicine, and Society for Vascular Surgery..J Vasc Surg 2011;54:e32–58 Rooke TW, Hirsch AT, Misra S et al. 2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral artery disease (updating the 2005 guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society for Vascular Medicine, and Society for Vascular Surgery..J Vasc Surg 2011;54:e32–58
20.
Zurück zum Zitat Jones WS, Schmit KM, Vemulapalli S et al. Treatment strategies for patients with peripheral artery disease [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US);2013 May. Report No.: 13-EHC090-EF. AHRQ Comparative Effectiveness Reviews. Jones WS, Schmit KM, Vemulapalli S et al. Treatment strategies for patients with peripheral artery disease [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US);2013 May. Report No.: 13-EHC090-EF. AHRQ Comparative Effectiveness Reviews.
21.
Zurück zum Zitat World Health Organization. Prevention of Cardiovascular Disease. Pocket guidelines for assessment and management of cardiovascular risk. Geneva, 2007 [http://www.who.int/cardiovascular_diseases/guidelines/PocketGL.ENGLISH.AFR-D-E.rev1.pdf] World Health Organization. Prevention of Cardiovascular Disease. Pocket guidelines for assessment and management of cardiovascular risk. Geneva, 2007 [http://​www.​who.​int/​cardiovascular_​diseases/​guidelines/​PocketGL.​ENGLISH.​AFR-D-E.​rev1.​pdf]
22.
Zurück zum Zitat Bisdas T, Stachmann A, Weiss K, Borowski M, Grundmann RT, Torsello G Nationales Register für die Erstlinie-Therapiestrategien in Patienten mit kritischer Extremitätenischämie (CRITISCH Register): Studiendesign und aktueller Stand. Gefäßchirurgie 2014, in Druck Bisdas T, Stachmann A, Weiss K, Borowski M, Grundmann RT, Torsello G Nationales Register für die Erstlinie-Therapiestrategien in Patienten mit kritischer Extremitätenischämie (CRITISCH Register): Studiendesign und aktueller Stand. Gefäßchirurgie 2014, in Druck
23.
Zurück zum Zitat Flu HC, Tamsma JT, Lindeman JH, Hamming JF, Lardenoye JH. A systematic review of implementation of established recommended secondary prevention measures in patients with PAOD. Eur J Vasc Endovasc Surg 2010;39:70–86PubMedCrossRef Flu HC, Tamsma JT, Lindeman JH, Hamming JF, Lardenoye JH. A systematic review of implementation of established recommended secondary prevention measures in patients with PAOD. Eur J Vasc Endovasc Surg 2010;39:70–86PubMedCrossRef
24.
Zurück zum Zitat Welten GM, Schouten O, Hoeks SE et al. Long-term prognosis of patients with peripheral arterial disease: a comparison in patients with coronary artery disease. J Am Coll Cardiol 2008;51:1588–1596PubMedCrossRef Welten GM, Schouten O, Hoeks SE et al. Long-term prognosis of patients with peripheral arterial disease: a comparison in patients with coronary artery disease. J Am Coll Cardiol 2008;51:1588–1596PubMedCrossRef
25.
Zurück zum Zitat Bhatt DL, Steg PG, Ohman EM et al. REACH Registry Investigators. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006;295:180–189PubMedCrossRef Bhatt DL, Steg PG, Ohman EM et al. REACH Registry Investigators. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006;295:180–189PubMedCrossRef
26.
Zurück zum Zitat Rodriguez F, Cannon CP, Steg PG et al. On behalf of the REACH Registry Investigators. Predictors of long-term adherence to evidence-based cardiovascular disease medications in outpatients with stable atherothrombotic disease: findings from the REACH Registry. Clin Cardiol. 2013 Oct 25 doi: 10.1002/clc.22217 [Epub ahead of print] Rodriguez F, Cannon CP, Steg PG et al. On behalf of the REACH Registry Investigators. Predictors of long-term adherence to evidence-based cardiovascular disease medications in outpatients with stable atherothrombotic disease: findings from the REACH Registry. Clin Cardiol. 2013 Oct 25 doi: 10.​1002/​clc.​22217 [Epub ahead of print]
27.
Zurück zum Zitat Kumbhani DJ, Steg PG, Cannon CP et al. Reduction of Atherothrombosis for Continued Health Registry Investigators. Adherence to secondary prevention medications and four-year outcomes in outpatients with atherosclerosis. Am J Med 2013;126:693–700PubMedCrossRef Kumbhani DJ, Steg PG, Cannon CP et al. Reduction of Atherothrombosis for Continued Health Registry Investigators. Adherence to secondary prevention medications and four-year outcomes in outpatients with atherosclerosis. Am J Med 2013;126:693–700PubMedCrossRef
28.
Zurück zum Zitat Jahn R, Diehm C, Lux G et al. Patient Care Evaluation - Peripheral Arterial Disease (PACE-PAD) Study Investigators. Effect of guideline orientation on the outcomes of peripheral arterial disease in primary care. Curr Med Res Opin 2011;27:1183–1190PubMedCrossRef Jahn R, Diehm C, Lux G et al. Patient Care Evaluation - Peripheral Arterial Disease (PACE-PAD) Study Investigators. Effect of guideline orientation on the outcomes of peripheral arterial disease in primary care. Curr Med Res Opin 2011;27:1183–1190PubMedCrossRef
29.
Zurück zum Zitat Hoel AW, Nolan BW, Goodney PP et al. Vascular Study Group of New England. Variation in smoking cessation after vascular operations. J Vasc Surg 2013;57:1338–1344PubMedCrossRef Hoel AW, Nolan BW, Goodney PP et al. Vascular Study Group of New England. Variation in smoking cessation after vascular operations. J Vasc Surg 2013;57:1338–1344PubMedCrossRef
Metadaten
Titel
Sind Sie sich dieser Gefahr bewusst?
Die periphere arterielle Verschlusskrankheit
verfasst von
Prof. Dr. med. E. Sebastian Debus
Prof. Dr. med. Giovanni Torsello
Prof. Dr. med. Thomas Hupp
Prof. Dr. med. Martin Storck
Prof. Dr. med. Werner Lang
Prof. Dr. med. Reinhart T. Grundmann
Publikationsdatum
21.08.2014
Verlag
Urban & Vogel
Erschienen in
MMW - Fortschritte der Medizin / Ausgabe 14/2014
Print ISSN: 1438-3276
Elektronische ISSN: 1613-3560
DOI
https://doi.org/10.1007/s15006-014-3095-6

Weitere Artikel der Ausgabe 14/2014

MMW - Fortschritte der Medizin 14/2014 Zur Ausgabe

GESCHICHTEN AUS DER PRAXIS_WAS MMW-LESER ERLEBEN

Das Saturnekzem

AUS DER PRAXIS_MMW-HOTLINE

Neue Ziffern, neue Strategie

Leitlinien kompakt für die Allgemeinmedizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Facharzt-Training Allgemeinmedizin

Die ideale Vorbereitung zur anstehenden Prüfung mit den ersten 24 von 100 klinischen Fallbeispielen verschiedener Themenfelder

Mehr erfahren

Update Allgemeinmedizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.