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Erschienen in: Die Dermatologie 9/2019

05.08.2019 | Systemische Sklerodermie | CME

Systemische Sklerose – klinisches Bild, Diagnostik und Therapie

verfasst von: Dr. med. M. O. Becker, O. Distler, B. Maurer

Erschienen in: Die Dermatologie | Ausgabe 9/2019

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Zusammenfassung

Die systemische Sklerose ist eine seltene rheumatische Erkrankung, die durch Haut- und Organfibrose, vaskuläre Veränderungen und das Auftreten spezifischer Autoantikörper charakterisiert ist. Sie zeigt eine hohe Morbidität und Mortalität, weist dabei aber in ihrem Verlauf und den Manifestationen eine beträchtliche Heterogenität auf. Dies macht eine umfassende Diagnostik zur Diagnosestellung und bei den Verlaufsuntersuchungen notwendig, da auch die Therapie den jeweiligen Krankheitsmanifestationen angepasst werden muss. Obwohl spezifische Therapien für gastrointestinale, pulmonale oder auch vaskuläre Komplikationen existieren, sprechen die Patienten meistens nur teilweise an und neue Therapieansätze sind notwendig.
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Metadaten
Titel
Systemische Sklerose – klinisches Bild, Diagnostik und Therapie
verfasst von
Dr. med. M. O. Becker
O. Distler
B. Maurer
Publikationsdatum
05.08.2019
Verlag
Springer Medizin
Erschienen in
Die Dermatologie / Ausgabe 9/2019
Print ISSN: 2731-7005
Elektronische ISSN: 2731-7013
DOI
https://doi.org/10.1007/s00105-019-4454-0

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