Erschienen in:
26.08.2021 | Methods • Review
Sleep duration and health outcomes: an umbrella review
verfasst von:
Jin Li, Dehong Cao, Yin Huang, Zeyu Chen, Ruyi Wang, Qiang Dong, Qiang Wei, Liangren Liu
Erschienen in:
Sleep and Breathing
|
Ausgabe 3/2022
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Abstract
Purpose
To collect existing evidence on the relationship between sleep duration and health outcomes.
Methods
A thorough search was conducted in PubMed, Web of Science, Embase, and the Cochrane Database of Systematic Reviews from inception to January, 2021. Meta-analyses of observational and interventional studies were eligible if they examined the associations between sleep duration and human health.
Results
In total, this umbrella review identified 69 meta-analyses with 11 outcomes for cancers and 30 outcomes for non-cancer conditions. Inappropriate sleep durations may significantly elevate the risk for cardiovascular disease (CVD), cognitive decline, coronary heart disease (CHD), depression, falls, frailty, lung cancer, metabolic syndrome (MS), and stroke. Dose–response analysis revealed that a 1-h reduction per 24 hours is associated with an increased risk by 3–11% of all-cause mortality, CHD, osteoporosis, stroke, and T2DM among short sleepers. Conversely, a 1-h increment in long sleepers is associated with a 7–17% higher risk of stroke mortality, CHD, stroke, and T2DM in adults.
Conclusion
Inappropriate sleep duration is a risk factor for developing non-cancer conditions. Decreasing and increasing sleep hours towards extreme sleep durations are associated with poor health outcomes.